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• W2897591401 abstract "To study the correlation between placental volume and vascularisation indices in first trimester with birthweight. This is an observational study, conducted from July 2015 to June 2017 at All India Institute of Medical Sciences, India. Low risk, pregnant women between 11 and 13 + 6 weeks gestation with live singleton pregnancy were recruited in this study. Women with difference of > 6 days in gestational age by LMP and CRL were excluded. At 11 and 13 + 6 weeks scan, CRL and nuchal translucency was measured (FMF guidelines). Placental volume and placental vascularisation indices were calculated using 3D power Doppler and the virtual organ computer-aided analysis (VOCAL) in Voluson E-8, ultrasound machine (GE Medical systems). Vascularisation indices determined were vascularisation index (VI), flow index (FI) and vascularisation flow index (VFI). Participants underwent routine antenatal care. Pregnancy outcomes noted were mode of delivery, period of gestation at birth, birthweight and any pregnancy related complications. For purpose of analysis placental volumes were expressed as MOM. 168 women completed the study. The mean age was 28.08± 3.2 yrs, mean BMI was 23.93 ± 12.51, mean gestation at recruitment was 12.5 ± .67 weeks, mean gestation at delivery was 38.7 ± 1.3 weeks and mean birthweight was 2917 ± 384 gms. Mean placental volume was 51.62 ± 17.24 cm3, mean VI – 41.27 ± 11.03, mean FI- 32.85 ± 5.58 and mean VFI was 13.80 ± 4.66. Placental volume correlated with CRL (r=0.486; p = 0.000). First trimester placental volume significantly correlated with birthweight, adjusted for gestational age (r = 0.266; p = 0.00). There was a correlation between VI (r=0.164, p = .034), FI (r =0.245, p = .001), VFI (r =0.24, p = .002) and birthweight. First trimester placental volume was not significantly smaller in SGA neonates (n=15) but was significantly more in 21 LGA neonates (p=0.017) compared to AGA neonates. First trimester placental volume and vascular indices correlated with birthweight. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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• W2897591401 date "2018-10-01" @default.
• W2897591401 modified "2023-09-24" @default.
• W2897591401 title "OP12.01: Correlation of placental volume and vascular indices in first trimester with birthweight" @default.
• W2897591401 doi "https://doi.org/10.1002/uog.19493" @default.
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