FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897595861> ?p ?o ?g. }

• W2897595861 endingPage "386" @default.
• W2897595861 startingPage "375" @default.
• W2897595861 abstract "<b><i>Background:</i></b> The World Health Organization (WHO) and the American Joint Cancer Committee (AJCC) modified the grading of pancreatic neuroendocrine neoplasms from a three-tier (WHO-AJCC 2010) to a four-tier system by introducing the novel category of NET G3 (WHO-AJCC 2017). <b><i>Objectives:</i></b> This study aims at validating the WHO-AJCC 2017 and identifying the most effective grading system. <b><i>Method:</i></b> A total of 2,102 patients were enrolled; entry criteria were: (i) patient underwent surgery; (ii) at least 2 years of follow-up; (iii) observation time up to 2015. Data from 34 variables were collected; grading was assessed and compared for efficacy by statistical means including Kaplan-Meier method, Cox regression analysis, Harrell’s C statistics, and Royston’s explained variation in univariable and multivariable analyses. <b><i>Results:</i></b> In descriptive analysis, the two grading systems demonstrated statistically significant differences for the major category sex but not for age groups. In Cox regression analysis, both grading systems showed statistically significant differences between grades for OS and EFS; however, no statistically significant difference was observed between the two G3 classes of WHO-AJCC 2017. In multivariable analysis for the two models fitted to compare efficacy, the two grading systems performed equally well with substantially similar optimal discrimination and well-explained variation for both OS and EFS. The WHO-AJCC 2017 grading system retained statistically significant difference between the two G3 classes for OS but not for EFS. <b><i>Conclusions:</i></b> The WHO-AJCC 2017 grading system is at least equally performing as the WHO-AJCC 2010 but allows the successful identification of the most aggressive PanNET subgroup. Grading is confirmed as probably the most powerful tool for predicting patient survival." @default.
• W2897595861 created "2018-10-26" @default.
• W2897595861 creator A5003467210 @default.
• W2897595861 creator A5003507376 @default.
• W2897595861 creator A5006430726 @default.
• W2897595861 creator A5006457492 @default.
• W2897595861 creator A5007891817 @default.
• W2897595861 creator A5010371525 @default.
• W2897595861 creator A5013034674 @default.
• W2897595861 creator A5015987727 @default.
• W2897595861 creator A5020689059 @default.
• W2897595861 creator A5021643347 @default.
• W2897595861 creator A5022410426 @default.
• W2897595861 creator A5023302477 @default.
• W2897595861 creator A5023956790 @default.
• W2897595861 creator A5026573275 @default.
• W2897595861 creator A5030128430 @default.
• W2897595861 creator A5033623007 @default.
• W2897595861 creator A5036032282 @default.
• W2897595861 creator A5036546967 @default.
• W2897595861 creator A5038551333 @default.
• W2897595861 creator A5038626624 @default.
• W2897595861 creator A5040724230 @default.
• W2897595861 creator A5044729691 @default.
• W2897595861 creator A5046167689 @default.
• W2897595861 creator A5047380313 @default.
• W2897595861 creator A5048428328 @default.
• W2897595861 creator A5048652672 @default.
• W2897595861 creator A5049004748 @default.
• W2897595861 creator A5049553183 @default.
• W2897595861 creator A5050689592 @default.
• W2897595861 creator A5056214075 @default.
• W2897595861 creator A5056434228 @default.
• W2897595861 creator A5057380925 @default.
• W2897595861 creator A5058080722 @default.
• W2897595861 creator A5060346666 @default.
• W2897595861 creator A5062125611 @default.
• W2897595861 creator A5063135890 @default.
• W2897595861 creator A5063169537 @default.
• W2897595861 creator A5063976959 @default.
• W2897595861 creator A5067116958 @default.
• W2897595861 creator A5068259376 @default.
• W2897595861 creator A5071676789 @default.
• W2897595861 creator A5072356061 @default.
• W2897595861 creator A5073035695 @default.
• W2897595861 creator A5075107881 @default.
• W2897595861 creator A5085191142 @default.
• W2897595861 creator A5088475859 @default.
• W2897595861 date "2018-01-01" @default.
• W2897595861 modified "2023-10-17" @default.
• W2897595861 title "Competitive Testing of the WHO 2010 versus the WHO 2017 Grading of Pancreatic Neuroendocrine Neoplasms: Data from a Large International Cohort Study" @default.
• W2897595861 cites W1625637014 @default.
• W2897595861 cites W1840972930 @default.
• W2897595861 cites W1964586919 @default.
• W2897595861 cites W2063178653 @default.
• W2897595861 cites W2073757314 @default.
• W2897595861 cites W2085033505 @default.
• W2897595861 cites W2123060958 @default.
• W2897595861 cites W2129925362 @default.
• W2897595861 cites W2139082628 @default.
• W2897595861 cites W2156959065 @default.
• W2897595861 cites W2161676563 @default.
• W2897595861 cites W2167715386 @default.
• W2897595861 cites W2226067262 @default.
• W2897595861 cites W2290138226 @default.
• W2897595861 cites W2315116030 @default.
• W2897595861 cites W2410568505 @default.
• W2897595861 cites W2570536455 @default.
• W2897595861 cites W2573369749 @default.
• W2897595861 cites W2589112207 @default.
• W2897595861 cites W2591221157 @default.
• W2897595861 doi "https://doi.org/10.1159/000494355" @default.
• W2897595861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30300897" @default.
• W2897595861 hasPublicationYear "2018" @default.
• W2897595861 type Work @default.
• W2897595861 sameAs 2897595861 @default.
• W2897595861 citedByCount "73" @default.
• W2897595861 countsByYear W28975958612019 @default.
• W2897595861 countsByYear W28975958612020 @default.
• W2897595861 countsByYear W28975958612021 @default.
• W2897595861 countsByYear W28975958612022 @default.
• W2897595861 countsByYear W28975958612023 @default.
• W2897595861 crossrefType "journal-article" @default.
• W2897595861 hasAuthorship W2897595861A5003467210 @default.
• W2897595861 hasAuthorship W2897595861A5003507376 @default.
• W2897595861 hasAuthorship W2897595861A5006430726 @default.
• W2897595861 hasAuthorship W2897595861A5006457492 @default.
• W2897595861 hasAuthorship W2897595861A5007891817 @default.
• W2897595861 hasAuthorship W2897595861A5010371525 @default.
• W2897595861 hasAuthorship W2897595861A5013034674 @default.
• W2897595861 hasAuthorship W2897595861A5015987727 @default.
• W2897595861 hasAuthorship W2897595861A5020689059 @default.
• W2897595861 hasAuthorship W2897595861A5021643347 @default.
• W2897595861 hasAuthorship W2897595861A5022410426 @default.
• W2897595861 hasAuthorship W2897595861A5023302477 @default.
• W2897595861 hasAuthorship W2897595861A5023956790 @default.
• W2897595861 hasAuthorship W2897595861A5026573275 @default.
• W2897595861 hasAuthorship W2897595861A5030128430 @default.

• next