Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897601137> ?p ?o ?g. }
- W2897601137 endingPage "3758" @default.
- W2897601137 startingPage "3750" @default.
- W2897601137 abstract "Mitochondria are increasingly associated with inflammation. Here, we focus on the relationship between inflammation and adenine nucleotide translocator type 1 ( ANT 1), which is localized in the mitochondrial inner membrane. ANT 1 plays an important role in oxidative phosphorylation, and mutations in the ANT 1 gene are responsible for mitochondrial diseases. Ample studies have demonstrated that ANT 1 has a critical role in cardiomyocytes and neurons, but little has been reported on its functions in immune cells. We knocked down ANT 1 expression in macrophages and examined inflammatory cytokine expression after lipopolysaccharide stimulation. ANT 1 knockdown reduces the expression of IL ‐6. JNK , upstream of IL ‐6, is downregulated, but other MAP kinases and the NF ‐κB signaling remain unchanged. These results suggest that ANT 1 modulates IL ‐6 expression through JNK in macrophages." @default.
- W2897601137 created "2018-10-26" @default.
- W2897601137 creator A5005226273 @default.
- W2897601137 creator A5012893729 @default.
- W2897601137 creator A5021375192 @default.
- W2897601137 creator A5025645497 @default.
- W2897601137 creator A5026251829 @default.
- W2897601137 creator A5056345650 @default.
- W2897601137 creator A5069810611 @default.
- W2897601137 date "2018-10-24" @default.
- W2897601137 modified "2023-10-16" @default.
- W2897601137 title "The inner mitochondrial membrane protein<scp>ANT</scp>1 modulates<scp>IL</scp>‐6 expression<i>via</i>the<scp>JNK</scp>pathway in macrophages" @default.
- W2897601137 cites W1963699887 @default.
- W2897601137 cites W1985538633 @default.
- W2897601137 cites W1992841021 @default.
- W2897601137 cites W2000571814 @default.
- W2897601137 cites W2002139629 @default.
- W2897601137 cites W2004499394 @default.
- W2897601137 cites W2014140871 @default.
- W2897601137 cites W2029144840 @default.
- W2897601137 cites W2033448006 @default.
- W2897601137 cites W2041419269 @default.
- W2897601137 cites W2068048197 @default.
- W2897601137 cites W2086327820 @default.
- W2897601137 cites W2099445613 @default.
- W2897601137 cites W2275879522 @default.
- W2897601137 cites W2329561586 @default.
- W2897601137 cites W2526186260 @default.
- W2897601137 cites W2589759270 @default.
- W2897601137 cites W2602809814 @default.
- W2897601137 cites W2775320826 @default.
- W2897601137 doi "https://doi.org/10.1002/1873-3468.13269" @default.
- W2897601137 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30311946" @default.
- W2897601137 hasPublicationYear "2018" @default.
- W2897601137 type Work @default.
- W2897601137 sameAs 2897601137 @default.
- W2897601137 citedByCount "2" @default.
- W2897601137 countsByYear W28976011372020 @default.
- W2897601137 countsByYear W28976011372022 @default.
- W2897601137 crossrefType "journal-article" @default.
- W2897601137 hasAuthorship W2897601137A5005226273 @default.
- W2897601137 hasAuthorship W2897601137A5012893729 @default.
- W2897601137 hasAuthorship W2897601137A5021375192 @default.
- W2897601137 hasAuthorship W2897601137A5025645497 @default.
- W2897601137 hasAuthorship W2897601137A5026251829 @default.
- W2897601137 hasAuthorship W2897601137A5056345650 @default.
- W2897601137 hasAuthorship W2897601137A5069810611 @default.
- W2897601137 hasBestOaLocation W28976011371 @default.
- W2897601137 hasConcept C11960822 @default.
- W2897601137 hasConcept C173396325 @default.
- W2897601137 hasConcept C184235292 @default.
- W2897601137 hasConcept C185592680 @default.
- W2897601137 hasConcept C18903297 @default.
- W2897601137 hasConcept C190283241 @default.
- W2897601137 hasConcept C203014093 @default.
- W2897601137 hasConcept C2776024035 @default.
- W2897601137 hasConcept C2776914184 @default.
- W2897601137 hasConcept C2778754761 @default.
- W2897601137 hasConcept C28859421 @default.
- W2897601137 hasConcept C55493867 @default.
- W2897601137 hasConcept C75385678 @default.
- W2897601137 hasConcept C86803240 @default.
- W2897601137 hasConcept C95444343 @default.
- W2897601137 hasConcept C97467695 @default.
- W2897601137 hasConceptScore W2897601137C11960822 @default.
- W2897601137 hasConceptScore W2897601137C173396325 @default.
- W2897601137 hasConceptScore W2897601137C184235292 @default.
- W2897601137 hasConceptScore W2897601137C185592680 @default.
- W2897601137 hasConceptScore W2897601137C18903297 @default.
- W2897601137 hasConceptScore W2897601137C190283241 @default.
- W2897601137 hasConceptScore W2897601137C203014093 @default.
- W2897601137 hasConceptScore W2897601137C2776024035 @default.
- W2897601137 hasConceptScore W2897601137C2776914184 @default.
- W2897601137 hasConceptScore W2897601137C2778754761 @default.
- W2897601137 hasConceptScore W2897601137C28859421 @default.
- W2897601137 hasConceptScore W2897601137C55493867 @default.
- W2897601137 hasConceptScore W2897601137C75385678 @default.
- W2897601137 hasConceptScore W2897601137C86803240 @default.
- W2897601137 hasConceptScore W2897601137C95444343 @default.
- W2897601137 hasConceptScore W2897601137C97467695 @default.
- W2897601137 hasIssue "22" @default.
- W2897601137 hasLocation W28976011371 @default.
- W2897601137 hasLocation W28976011372 @default.
- W2897601137 hasOpenAccess W2897601137 @default.
- W2897601137 hasPrimaryLocation W28976011371 @default.
- W2897601137 hasRelatedWork W1964678730 @default.
- W2897601137 hasRelatedWork W1992168954 @default.
- W2897601137 hasRelatedWork W2018832587 @default.
- W2897601137 hasRelatedWork W2063553111 @default.
- W2897601137 hasRelatedWork W2075952537 @default.
- W2897601137 hasRelatedWork W2128475404 @default.
- W2897601137 hasRelatedWork W2211481535 @default.
- W2897601137 hasRelatedWork W2908443539 @default.
- W2897601137 hasRelatedWork W3197367765 @default.
- W2897601137 hasRelatedWork W4225422843 @default.
- W2897601137 hasVolume "592" @default.
- W2897601137 isParatext "false" @default.
- W2897601137 isRetracted "false" @default.