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• W2897631477 abstract "A series of novel coumarin derivatives carrying 1,2,4-triazole or 1,2,4-triazolo[3,4- b ][1,3,4]thiadiazole moieties were prepared and evaluated in vitro as anticancer in the human colon cancer (HCT116) cell line. The derivatives 4c and 8c exhibited marked anticancer activity with IC 50 values 4.363 and 2.656 µ M, respectively. The molecular docking studies suggested possible interaction with tyrosine kinases (CDK2)." @default.
• W2897631477 created "2018-10-26" @default.
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• W2897631477 date "2018-10-14" @default.
• W2897631477 modified "2023-09-25" @default.
• W2897631477 title "Synthesis of Novel 1,2,4-Triazolyl Coumarin Derivatives as Potential Anticancer Agents" @default.
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• W2897631477 doi "https://doi.org/10.1155/2018/5201374" @default.
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