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- W2897632051 abstract "We performed pathological and molecular virological investigation of three outbreaks of highly pathogenic avian influenza (HPAI) in a quail farm and two duck farms of Mymensingh and Netrokona districts of Bangladesh in 2011. HPAI viruses of subtype H5N1 were detected from all three outbreaks and phylogenetic analysis of HA gene sequence placed the viruses into clade 2.3.2.1. The outbreak in the quail farm was characterized by acute death with 100% mortality within two days. Marked haemorrhages and congestion with necrotic and inflammatory lesions in the respiratory tract, liver, pancreas and kidneys were the major gross and histopathological lesions. In the case of ducks, nervous signs were the remarkable clinical manifestations and the mortality was around 10%. No significant gross lesions were observed at necropsy. Non-purulent encephalitis with gliosis and neuronal degeneration was observed on histopathological examination. By immunohistochemistry, viral antigen could be detected in different organs of both quails and ducks. This study records varying clinical and pathological manifestations of HPAI in ducks and quails following natural infection with the same strain of the virus.RESEARCH HIGHLIGHTS HPAIV of clade 2.3.2.1 was detected from clinical outbreaks in quails and ducksSudden death with severe haemorrhages in various organs was found in quailsPronounced nervous signs with non-purulent encephalitis were observed in ducksViral antigen could be localized in different organs by immunohistochemistry" @default.
- W2897632051 created "2018-10-26" @default.
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- W2897632051 date "2018-10-25" @default.
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- W2897632051 title "Pathology of clade 2.3.2.1 avian influenza virus (H5N1) infection in quails and ducks in Bangladesh" @default.
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- W2897632051 doi "https://doi.org/10.1080/03079457.2018.1535165" @default.
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