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- W2897657473 abstract "The Montreal Cognitive Assessment (MoCA), developed in 2005, is used as a screening tool for Mild Cognitive Impairment (MCI). The MoCA has a high sensitivity for detection of MCI in patients who would score as normal on the Mini Mental State Examination, however, its widely established cut-off of 26 for impairment may not be optimal for use in minority populations. Data come from the National Alzheimer's Coordinating Center's (NACC) Uniform Data Set (UDS) for visits conducted until the December 2017 data freeze. Participants who completed a MoCA at their baseline visit and reported being either non-Hispanic white, non-Hispanic black, or Hispanic were included in this analysis (n=3,539). SAS 9.4 was used to calculate descriptive statistics. Of the participants included in this analysis, 69.4 years old on the average, 81.2% were non-Hispanic white, 13.9% were non-Hispanic black, and 4.9% were Hispanic. Most had normal cognition (47.0%), as judged by a clinician, and the average raw MoCA score was 22.3. Using the cut-off of 26, the sensitivity of the MoCA was 87.4% in non-Hispanic whites, 94.3% in non-Hispanic blacks, and 93.8% in Hispanics; the specificity of the MoCA was 73.8% in non-Hispanic whites, 37.3% in non-Hispanic blacks, and 49.4% in Hispanics; the positive predictive value of the MoCA was 80.0% in non-Hispanic whites, 53.3% in non-Hispanic blacks, and 69.2% in Hispanics. Differences observed may be due to a lack of cultural equivalence of test items or to differential variability in MoCA score by race/ethnicity. The low specificity and positive predictive value of the MoCA observed in non-Hispanic blacks and Hispanics highlight a need to further investigate more appropriate cut-offs in minority groups to correctly identify cognitive impairment. Given the diversity if the United States population such norms will become increasingly important." @default.
- W2897657473 created "2018-10-26" @default.
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- W2897657473 date "2018-07-01" @default.
- W2897657473 modified "2023-10-16" @default.
- W2897657473 title "P2‐576: SENSITIVITY AND SPECIFICITY OF THE MONTREAL COGNITIVE ASSESSMENT AMONG MINORITY POPULATIONS" @default.
- W2897657473 doi "https://doi.org/10.1016/j.jalz.2018.06.1271" @default.
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