Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897703516> ?p ?o ?g. }
- W2897703516 endingPage "1509" @default.
- W2897703516 startingPage "1493" @default.
- W2897703516 abstract "A brief historical background of the development of the theranostic approach in nuclear medicine is given and seven theranostic pairs of radionuclides, namely 44gSc/47Sc, 64Cu/67Cu, 83Sr/89Sr, 86Y/90Y, 124I/131I, 152Tb/161Tb and 152Tb/149Tb, are considered. The first six pairs consist of a positron and a β−-emitter whereas the seventh pair consists of a positron and an α-particle emitter. The decay properties of all those radionuclides are briefly mentioned and their production methodologies are discussed. The positron emitters 64Cu, 86Y and 124I are commonly produced in sufficient quantities via the (p,n) reaction on the respective highly enriched target isotope. A clinical scale production of the positron emitter 44gSc has been achieved via the generator route as well as via the (p,n) reaction, but further development work is necessary. The positron emitters 83Sr and 152Tb are under development. Among the therapeutic radionuclides, 89Sr, 90Y and 131I are commercially available and 161Tb can also be produced in sufficient quantity at a nuclear reactor. Great efforts are presently underway to produce 47Sc and 67Cu via neutron, photon and charged particle induced reactions. The radionuclide 149Tb is unique because it is an α-particle emitter. The present method of production of 152Tb and 149Tb involves the use of the spallation process in combination with an on-line mass separator. The role of some emerging irradiation facilities in the production of special radionuclides is discussed." @default.
- W2897703516 created "2018-10-26" @default.
- W2897703516 creator A5013375306 @default.
- W2897703516 creator A5064685340 @default.
- W2897703516 creator A5076382838 @default.
- W2897703516 date "2018-10-19" @default.
- W2897703516 modified "2023-10-14" @default.
- W2897703516 title "New developments in the production of theranostic pairs of radionuclides" @default.
- W2897703516 cites W1205543341 @default.
- W2897703516 cites W1551338091 @default.
- W2897703516 cites W1583854931 @default.
- W2897703516 cites W1685573976 @default.
- W2897703516 cites W1766489425 @default.
- W2897703516 cites W1873143726 @default.
- W2897703516 cites W1964161776 @default.
- W2897703516 cites W1966018242 @default.
- W2897703516 cites W1966730843 @default.
- W2897703516 cites W1966816065 @default.
- W2897703516 cites W1967598597 @default.
- W2897703516 cites W1968368106 @default.
- W2897703516 cites W1970014559 @default.
- W2897703516 cites W1970405229 @default.
- W2897703516 cites W1971011523 @default.
- W2897703516 cites W1972332231 @default.
- W2897703516 cites W1973259264 @default.
- W2897703516 cites W1974629985 @default.
- W2897703516 cites W1976792913 @default.
- W2897703516 cites W1977565605 @default.
- W2897703516 cites W1980411922 @default.
- W2897703516 cites W1981240010 @default.
- W2897703516 cites W1988451067 @default.
- W2897703516 cites W1988954531 @default.
- W2897703516 cites W1993704493 @default.
- W2897703516 cites W1994475200 @default.
- W2897703516 cites W1996908061 @default.
- W2897703516 cites W1999924649 @default.
- W2897703516 cites W2000253410 @default.
- W2897703516 cites W2004142046 @default.
- W2897703516 cites W2005325054 @default.
- W2897703516 cites W2009758848 @default.
- W2897703516 cites W2012240290 @default.
- W2897703516 cites W2012744044 @default.
- W2897703516 cites W2013304102 @default.
- W2897703516 cites W2013982526 @default.
- W2897703516 cites W2014164339 @default.
- W2897703516 cites W2014749084 @default.
- W2897703516 cites W2017402109 @default.
- W2897703516 cites W2018014101 @default.
- W2897703516 cites W2018220772 @default.
- W2897703516 cites W2019753861 @default.
- W2897703516 cites W2019922318 @default.
- W2897703516 cites W2020450281 @default.
- W2897703516 cites W2020824334 @default.
- W2897703516 cites W2021671793 @default.
- W2897703516 cites W2022286689 @default.
- W2897703516 cites W2023028584 @default.
- W2897703516 cites W2024137519 @default.
- W2897703516 cites W2027185975 @default.
- W2897703516 cites W2027864396 @default.
- W2897703516 cites W2028459481 @default.
- W2897703516 cites W2029163989 @default.
- W2897703516 cites W2029548893 @default.
- W2897703516 cites W2031013364 @default.
- W2897703516 cites W2032359818 @default.
- W2897703516 cites W2032789268 @default.
- W2897703516 cites W2033646550 @default.
- W2897703516 cites W2034711346 @default.
- W2897703516 cites W2039323999 @default.
- W2897703516 cites W2039464129 @default.
- W2897703516 cites W2042404085 @default.
- W2897703516 cites W2042950696 @default.
- W2897703516 cites W2045010380 @default.
- W2897703516 cites W2047647660 @default.
- W2897703516 cites W2051549313 @default.
- W2897703516 cites W2052635554 @default.
- W2897703516 cites W2052755039 @default.
- W2897703516 cites W2055016798 @default.
- W2897703516 cites W2055219205 @default.
- W2897703516 cites W2055354037 @default.
- W2897703516 cites W2056061805 @default.
- W2897703516 cites W2056985174 @default.
- W2897703516 cites W2058044363 @default.
- W2897703516 cites W2061757241 @default.
- W2897703516 cites W2066902301 @default.
- W2897703516 cites W2067206809 @default.
- W2897703516 cites W2071089689 @default.
- W2897703516 cites W2076669662 @default.
- W2897703516 cites W2077216350 @default.
- W2897703516 cites W2079527812 @default.
- W2897703516 cites W2083611760 @default.
- W2897703516 cites W2083779481 @default.
- W2897703516 cites W2084023639 @default.
- W2897703516 cites W2085231359 @default.
- W2897703516 cites W2087135753 @default.
- W2897703516 cites W2087750103 @default.
- W2897703516 cites W2089056140 @default.
- W2897703516 cites W2089504378 @default.
- W2897703516 cites W2090222133 @default.