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- W2897710817 abstract "Abstract Objective The present study sought to investigate atherogenicity of alloxan-induced diabetic rats administered single and combinatorial herbal formulations of Acanthus montanus , Asystasia gangetica, Gongronema latifolium and Solanum melongena . Methods A single intra-peritoneal ( i.p. ) injection of 90 mg/kg b.w. of alloxan monohydrate was given to the rats to induce diabetes mellitus (DM). Serum lipid profiles were measured using standard spectrophotometric methods, whereas atherogenicity, serum lipid ratios and atherogenic coefficient/indices were calculated using standard formulae. Results Serum total cholesterol (TC) concentrations of experimental rat groups varied between 1.59 ± 0.10 mmol/L and 2.72 ± 0.16 mmol/L ( p p R 2 = 0.8275). Atherogenic protection of herbal extract treated DM-r groups was within the range of 33.4–81.7%. Conclusion The present study showed that double herbal formulations (DHFs): A. gangetica + G. latifolium and A. gangetica + A. montanus offered comparatively high protection to DM-r against atherogenic outcomes, which paralleled the capacities of these DHFs to reverse dyslipidemia." @default.
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- W2897710817 date "2018-12-01" @default.
- W2897710817 modified "2023-09-27" @default.
- W2897710817 title "Atherogenicity of diabetic rats administered single and combinatorial herbal extracts" @default.
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- W2897710817 doi "https://doi.org/10.1016/j.bfopcu.2018.10.001" @default.
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