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• W2897712440 abstract "Unlike the case of mammals, teleost fish generally have poor ability to utilize carbohydrate, and the clearance of glucose from the plasma is sluggish. In this study, after a 8-week feeding trial, we conducted a glucose tolerance test to hypothesize that the capability of grass carp (Ctenopharyngodon idellus) to clear a glucose load is associated with its nutrient history of different carbohydrate-to-lipid ratio diets (CHO:L: 1.52%, 5.84% and 34.84%) through glycogen synthesis and glucose metabolic key enzymes. Our results showed that after a glucose load, the plasma glucose of fish fed with high CHO:L-ratio diet (34.84%) first declined to baseline conditions, and the peak value of liver and muscle glycogen content was significantly higher in high CHO:L-ratio but lower in low CHO:L group (1.52%). In addition, after glucose administration, hepatic GK (glucokinase) activity of fish fed with high CHO:L-ratio diet increased more significantly than that of the other groups, and PEPCK (phosphoenolpyruvate carboxykinase) activity obviously decreased in low CHO:L-ratio group. The results indicated that a long-term adaptation to the high CHO:L-ratio diet can improved the glucose tolerance of C. idellus through the promotion of glycogen synthesis and GK activity." @default.
• W2897712440 created "2018-10-26" @default.
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• W2897712440 date "2018-10-14" @default.
• W2897712440 modified "2023-10-10" @default.
• W2897712440 title "Glucose tolerance of grass carp<i>Ctenopharyngodon idellus</i>after a long-term adaptation to carbohydrate-to-lipid ratio diets" @default.
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• W2897712440 doi "https://doi.org/10.1111/are.13856" @default.
• W2897712440 hasPublicationYear "2018" @default.
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