FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897712900> ?p ?o ?g. }

• W2897712900 endingPage "307" @default.
• W2897712900 startingPage "299" @default.
• W2897712900 abstract "Chronic hepatitis C (CHC)-related mortality generally results from cirrhosis and subsequent complications. We aimed to investigate the potential role of plasma bile acid levels and ABCB11 1331T > C (V444A, rs2287622) (ATP-binding cassette subfamily B, member 11) gene polymorphism in fibrosis prediction in CHC genotype 4 patients.This case control study included 85 healthy control and the following 225 subjects: 170 adult patients infected with hepatitis C virus (HCV) and categorized into three groups according to liver biopsy; no fibrosis group (F0) (n=33), early fibrosis group (F1-F2) (n=61), and advanced fibrosis group (F3-F4) (n=76). Fasting bile acid levels, hepatitis C virus (HCV) genotyping, and ABCB11 1331T > C gene polymorphism were assessed.The frequency of the variant homozygote genotype CC in advanced fibrosis was significantly higher than that in early fibrosis (48.7% vs. 36.1%) (odd ratio, OR =2.58; 95% confidence interval, CI=1.07-6.20; p=0.03). C allele was significantly represented in advanced fibrosis (65.8%) compared with that in early fibrosis (51.6%) (OR=1.80, 95% CI=1.10-2.93, p=0.01). A significant elevation of plasma bile acid levels in advanced fibrosis was observed compared with those in early fibrosis (p≤0.001). Receiver operating characteristic curve for plasma bile acid levels at cutoff value of 75.5 μmol/L had a 59% specificity and 97.4% sensitivity as a predictor of advanced hepatic fibrosis (AUROC=0.78%).We concluded that Egyptian patients having chronic hepatitis C genotype 4 with CC genotype of ABCB11 SNP 1331T > C and high plasma bile acid levels at cutoff value of 75.5 μmol/L were associated with advanced hepatic fibrosis." @default.
• W2897712900 created "2018-10-26" @default.
• W2897712900 creator A5006168556 @default.
• W2897712900 creator A5010159683 @default.
• W2897712900 creator A5017222133 @default.
• W2897712900 creator A5019134452 @default.
• W2897712900 creator A5020254144 @default.
• W2897712900 creator A5021500968 @default.
• W2897712900 creator A5022158572 @default.
• W2897712900 creator A5041426245 @default.
• W2897712900 creator A5044783774 @default.
• W2897712900 creator A5046274979 @default.
• W2897712900 creator A5047531494 @default.
• W2897712900 creator A5058780290 @default.
• W2897712900 creator A5072105938 @default.
• W2897712900 creator A5086475344 @default.
• W2897712900 date "2018-10-18" @default.
• W2897712900 modified "2023-10-16" @default.
• W2897712900 title "Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels" @default.
• W2897712900 cites W1977300462 @default.
• W2897712900 cites W2042732245 @default.
• W2897712900 cites W2047908520 @default.
• W2897712900 cites W2053513447 @default.
• W2897712900 cites W2061542347 @default.
• W2897712900 cites W2062455545 @default.
• W2897712900 cites W2087874793 @default.
• W2897712900 cites W2094174828 @default.
• W2897712900 cites W2095266553 @default.
• W2897712900 cites W2118476555 @default.
• W2897712900 cites W2132290252 @default.
• W2897712900 cites W2139008909 @default.
• W2897712900 cites W2159556063 @default.
• W2897712900 cites W2162578475 @default.
• W2897712900 cites W2171075953 @default.
• W2897712900 cites W2171107571 @default.
• W2897712900 cites W2176388629 @default.
• W2897712900 cites W2416448252 @default.
• W2897712900 cites W2570832918 @default.
• W2897712900 doi "https://doi.org/10.5152/tjg.2018.17570" @default.
• W2897712900 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6284664" @default.
• W2897712900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29755014" @default.
• W2897712900 hasPublicationYear "2018" @default.
• W2897712900 type Work @default.
• W2897712900 sameAs 2897712900 @default.
• W2897712900 citedByCount "17" @default.
• W2897712900 countsByYear W28977129002018 @default.
• W2897712900 countsByYear W28977129002019 @default.
• W2897712900 countsByYear W28977129002020 @default.
• W2897712900 countsByYear W28977129002021 @default.
• W2897712900 countsByYear W28977129002022 @default.
• W2897712900 countsByYear W28977129002023 @default.
• W2897712900 crossrefType "journal-article" @default.
• W2897712900 hasAuthorship W2897712900A5006168556 @default.
• W2897712900 hasAuthorship W2897712900A5010159683 @default.
• W2897712900 hasAuthorship W2897712900A5017222133 @default.
• W2897712900 hasAuthorship W2897712900A5019134452 @default.
• W2897712900 hasAuthorship W2897712900A5020254144 @default.
• W2897712900 hasAuthorship W2897712900A5021500968 @default.
• W2897712900 hasAuthorship W2897712900A5022158572 @default.
• W2897712900 hasAuthorship W2897712900A5041426245 @default.
• W2897712900 hasAuthorship W2897712900A5044783774 @default.
• W2897712900 hasAuthorship W2897712900A5046274979 @default.
• W2897712900 hasAuthorship W2897712900A5047531494 @default.
• W2897712900 hasAuthorship W2897712900A5058780290 @default.
• W2897712900 hasAuthorship W2897712900A5072105938 @default.
• W2897712900 hasAuthorship W2897712900A5086475344 @default.
• W2897712900 hasBestOaLocation W28977129002 @default.
• W2897712900 hasConcept C104317684 @default.
• W2897712900 hasConcept C126322002 @default.
• W2897712900 hasConcept C135763542 @default.
• W2897712900 hasConcept C203014093 @default.
• W2897712900 hasConcept C2522874641 @default.
• W2897712900 hasConcept C2775934546 @default.
• W2897712900 hasConcept C2776408679 @default.
• W2897712900 hasConcept C2776455275 @default.
• W2897712900 hasConcept C2777214474 @default.
• W2897712900 hasConcept C2777766500 @default.
• W2897712900 hasConcept C2780559512 @default.
• W2897712900 hasConcept C2993667909 @default.
• W2897712900 hasConcept C31467283 @default.
• W2897712900 hasConcept C54355233 @default.
• W2897712900 hasConcept C71924100 @default.
• W2897712900 hasConcept C86803240 @default.
• W2897712900 hasConcept C90924648 @default.
• W2897712900 hasConceptScore W2897712900C104317684 @default.
• W2897712900 hasConceptScore W2897712900C126322002 @default.
• W2897712900 hasConceptScore W2897712900C135763542 @default.
• W2897712900 hasConceptScore W2897712900C203014093 @default.
• W2897712900 hasConceptScore W2897712900C2522874641 @default.
• W2897712900 hasConceptScore W2897712900C2775934546 @default.
• W2897712900 hasConceptScore W2897712900C2776408679 @default.
• W2897712900 hasConceptScore W2897712900C2776455275 @default.
• W2897712900 hasConceptScore W2897712900C2777214474 @default.
• W2897712900 hasConceptScore W2897712900C2777766500 @default.
• W2897712900 hasConceptScore W2897712900C2780559512 @default.
• W2897712900 hasConceptScore W2897712900C2993667909 @default.
• W2897712900 hasConceptScore W2897712900C31467283 @default.
• W2897712900 hasConceptScore W2897712900C54355233 @default.

• next