Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897725718> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2897725718 endingPage "65" @default.
- W2897725718 startingPage "60" @default.
- W2897725718 abstract "GD2 is a ganglioside found in the plasma membrane of the neural crest-derived cancer, neuroblastoma. GD2 is shed into the circulation of patients with neuroblastoma and could serve as a tumor biomarker to monitor tumor burden or response to treatment. We developed and validated a high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method to quantify the D18:1-18:0 (C18) and the D18:1-20:0 (C20) lipoforms of GD2 in human plasma and serum. Human brain derived GD2 containing a mixture of C18 and C20 was used as the analytical standard. Samples were extracted with methanol containing dueterated-GM1 (internal standard), and analytes were separated on a Phenomenex Kinetex C18 column eluted with a gradient mobile phase composed of ammonium acetate buffer, methanol and isopropanol. An AB Sciex 4500 QTRAP mass spectrometer in negative ion mode was used to quantify the doubly charged GD2 C18 and C20 lipoform precursor ions (m/z 836.8 and m/z 850.8) that both yield a product ion of m/z 290.0. The calibration curves were linear from 4–1000 ng/mL and 6–1500 ng/mL for GD2 C18 and C20 lipoforms respectively. Inter-day and intra-day accuracy were within the acceptable validation range in plasma and serum." @default.
- W2897725718 created "2018-10-26" @default.
- W2897725718 creator A5024249524 @default.
- W2897725718 creator A5035557509 @default.
- W2897725718 creator A5050738935 @default.
- W2897725718 creator A5067159899 @default.
- W2897725718 creator A5070525030 @default.
- W2897725718 date "2018-12-01" @default.
- W2897725718 modified "2023-09-30" @default.
- W2897725718 title "A validated HPLC-MS/MS method for estimating the concentration of the ganglioside, GD2, in human plasma or serum" @default.
- W2897725718 cites W1511540332 @default.
- W2897725718 cites W1573445282 @default.
- W2897725718 cites W1965550919 @default.
- W2897725718 cites W2020395489 @default.
- W2897725718 cites W2027399451 @default.
- W2897725718 cites W2036929488 @default.
- W2897725718 cites W2076755974 @default.
- W2897725718 cites W2079188742 @default.
- W2897725718 cites W2080859163 @default.
- W2897725718 cites W2082029010 @default.
- W2897725718 cites W2086016597 @default.
- W2897725718 cites W2088687798 @default.
- W2897725718 cites W2092105992 @default.
- W2897725718 cites W2092526232 @default.
- W2897725718 cites W2093206478 @default.
- W2897725718 cites W2093540558 @default.
- W2897725718 cites W2128125459 @default.
- W2897725718 cites W2130275818 @default.
- W2897725718 cites W2135817296 @default.
- W2897725718 cites W2206963404 @default.
- W2897725718 doi "https://doi.org/10.1016/j.jchromb.2018.10.010" @default.
- W2897725718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30368044" @default.
- W2897725718 hasPublicationYear "2018" @default.
- W2897725718 type Work @default.
- W2897725718 sameAs 2897725718 @default.
- W2897725718 citedByCount "15" @default.
- W2897725718 countsByYear W28977257182019 @default.
- W2897725718 countsByYear W28977257182020 @default.
- W2897725718 countsByYear W28977257182021 @default.
- W2897725718 countsByYear W28977257182022 @default.
- W2897725718 countsByYear W28977257182023 @default.
- W2897725718 crossrefType "journal-article" @default.
- W2897725718 hasAuthorship W2897725718A5024249524 @default.
- W2897725718 hasAuthorship W2897725718A5035557509 @default.
- W2897725718 hasAuthorship W2897725718A5050738935 @default.
- W2897725718 hasAuthorship W2897725718A5067159899 @default.
- W2897725718 hasAuthorship W2897725718A5070525030 @default.
- W2897725718 hasConcept C10390740 @default.
- W2897725718 hasConcept C119128265 @default.
- W2897725718 hasConcept C162356407 @default.
- W2897725718 hasConcept C179998833 @default.
- W2897725718 hasConcept C185592680 @default.
- W2897725718 hasConcept C23531484 @default.
- W2897725718 hasConcept C2777331542 @default.
- W2897725718 hasConcept C2780782300 @default.
- W2897725718 hasConcept C31827203 @default.
- W2897725718 hasConcept C43617362 @default.
- W2897725718 hasConcept C55493867 @default.
- W2897725718 hasConcept C71043704 @default.
- W2897725718 hasConcept C95986675 @default.
- W2897725718 hasConceptScore W2897725718C10390740 @default.
- W2897725718 hasConceptScore W2897725718C119128265 @default.
- W2897725718 hasConceptScore W2897725718C162356407 @default.
- W2897725718 hasConceptScore W2897725718C179998833 @default.
- W2897725718 hasConceptScore W2897725718C185592680 @default.
- W2897725718 hasConceptScore W2897725718C23531484 @default.
- W2897725718 hasConceptScore W2897725718C2777331542 @default.
- W2897725718 hasConceptScore W2897725718C2780782300 @default.
- W2897725718 hasConceptScore W2897725718C31827203 @default.
- W2897725718 hasConceptScore W2897725718C43617362 @default.
- W2897725718 hasConceptScore W2897725718C55493867 @default.
- W2897725718 hasConceptScore W2897725718C71043704 @default.
- W2897725718 hasConceptScore W2897725718C95986675 @default.
- W2897725718 hasFunder F4320306589 @default.
- W2897725718 hasLocation W28977257181 @default.
- W2897725718 hasLocation W28977257182 @default.
- W2897725718 hasOpenAccess W2897725718 @default.
- W2897725718 hasPrimaryLocation W28977257181 @default.
- W2897725718 hasRelatedWork W1964888264 @default.
- W2897725718 hasRelatedWork W1972419240 @default.
- W2897725718 hasRelatedWork W2021008707 @default.
- W2897725718 hasRelatedWork W2064069181 @default.
- W2897725718 hasRelatedWork W2067719457 @default.
- W2897725718 hasRelatedWork W2079608352 @default.
- W2897725718 hasRelatedWork W2137436875 @default.
- W2897725718 hasRelatedWork W2141316828 @default.
- W2897725718 hasRelatedWork W2625685112 @default.
- W2897725718 hasRelatedWork W2799802339 @default.
- W2897725718 hasVolume "1102-1103" @default.
- W2897725718 isParatext "false" @default.
- W2897725718 isRetracted "false" @default.
- W2897725718 magId "2897725718" @default.
- W2897725718 workType "article" @default.