Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897726087> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2897726087 abstract "Objective Post-traumatic Stress Disorder (PTSD) occurs in people who suffers reparative shocking, scary, or dangerous event. Evidences demonstrate that PTSD is associated with cognitive decline and depression. In the general population, women tend to show higher incidence of PTSD compared with men. Using the the ovariectomized rat model, the present work was designed to investigate the potential beneficial effect of aerobic exercise on the prevention of PTSD.
 Methods Adult Sprague-Dawley male rats were randomly divided into the following four groups (n = 8-10 in each group): 1) naïve control group; 2) ovariectomized group (OVX), 3) OVX with PTSD group (OVX + PTSD), 4) OVX + exercise group (OVX + Exe), and 5) OVX + PTSD + exercise (OVX + PTSD + Exe). For exercise pretreatment groups, the rats were subjected to 30 min of treadmill exercise (30 min/day, 5 days / week) for continuous 4 weeks. Open field test and elevated plus maze were used to measure behavioral changes from day 59 to day 66. Hippocampal levels of 17β-estradiol (E2) and brain-derived neurotrophic factor (BDNF) level were measured.
 Results 1. Results of open field and elevated plus maze test revealed that OVX animals exposed to PTSD showed obvious anxiety-like behavior compared to OVX animals without exercise. Intriguingly, anxiety-like behavior in OVX + PTSD group was significantly improved by aerobic exercise pretreatment in ovariectomized animals after PTSD. 2. Hippocampal levels of E2 and BDNF levels in the OVX + Exe group were significantly increased after aerobic exercise compared to these from OVX without exercise group.
 Conclusions These findings demonstrated that aerobic exercise preconditioning can efficiently prevent anxiety-like behavior in the ovariectomized rats subjected to PTSD, a mechanism could be associate with the increased levels of E2 and BDNF induced by exercise treatment." @default.
- W2897726087 created "2018-10-26" @default.
- W2897726087 creator A5014569865 @default.
- W2897726087 creator A5042567804 @default.
- W2897726087 creator A5042812426 @default.
- W2897726087 creator A5059729786 @default.
- W2897726087 creator A5087063047 @default.
- W2897726087 creator A5088095668 @default.
- W2897726087 date "2018-10-04" @default.
- W2897726087 modified "2023-09-24" @default.
- W2897726087 title "PO-284 Aerobic Exercise Preconditioning Prevents Behavioral Deficits in an Ovariectomized Rat Model of Post-traumatic Stress Disorder" @default.
- W2897726087 doi "https://doi.org/10.14428/ebr.v1i5.12933" @default.
- W2897726087 hasPublicationYear "2018" @default.
- W2897726087 type Work @default.
- W2897726087 sameAs 2897726087 @default.
- W2897726087 citedByCount "0" @default.
- W2897726087 crossrefType "journal-article" @default.
- W2897726087 hasAuthorship W2897726087A5014569865 @default.
- W2897726087 hasAuthorship W2897726087A5042567804 @default.
- W2897726087 hasAuthorship W2897726087A5042812426 @default.
- W2897726087 hasAuthorship W2897726087A5059729786 @default.
- W2897726087 hasAuthorship W2897726087A5087063047 @default.
- W2897726087 hasAuthorship W2897726087A5088095668 @default.
- W2897726087 hasBestOaLocation W28977260871 @default.
- W2897726087 hasConcept C103038586 @default.
- W2897726087 hasConcept C118552586 @default.
- W2897726087 hasConcept C126322002 @default.
- W2897726087 hasConcept C134018914 @default.
- W2897726087 hasConcept C148762608 @default.
- W2897726087 hasConcept C15744967 @default.
- W2897726087 hasConcept C173586616 @default.
- W2897726087 hasConcept C2778159538 @default.
- W2897726087 hasConcept C2779085643 @default.
- W2897726087 hasConcept C2908647359 @default.
- W2897726087 hasConcept C558461103 @default.
- W2897726087 hasConcept C70410870 @default.
- W2897726087 hasConcept C71315377 @default.
- W2897726087 hasConcept C71924100 @default.
- W2897726087 hasConcept C8264082 @default.
- W2897726087 hasConcept C99454951 @default.
- W2897726087 hasConceptScore W2897726087C103038586 @default.
- W2897726087 hasConceptScore W2897726087C118552586 @default.
- W2897726087 hasConceptScore W2897726087C126322002 @default.
- W2897726087 hasConceptScore W2897726087C134018914 @default.
- W2897726087 hasConceptScore W2897726087C148762608 @default.
- W2897726087 hasConceptScore W2897726087C15744967 @default.
- W2897726087 hasConceptScore W2897726087C173586616 @default.
- W2897726087 hasConceptScore W2897726087C2778159538 @default.
- W2897726087 hasConceptScore W2897726087C2779085643 @default.
- W2897726087 hasConceptScore W2897726087C2908647359 @default.
- W2897726087 hasConceptScore W2897726087C558461103 @default.
- W2897726087 hasConceptScore W2897726087C70410870 @default.
- W2897726087 hasConceptScore W2897726087C71315377 @default.
- W2897726087 hasConceptScore W2897726087C71924100 @default.
- W2897726087 hasConceptScore W2897726087C8264082 @default.
- W2897726087 hasConceptScore W2897726087C99454951 @default.
- W2897726087 hasLocation W28977260871 @default.
- W2897726087 hasOpenAccess W2897726087 @default.
- W2897726087 hasPrimaryLocation W28977260871 @default.
- W2897726087 hasRelatedWork W1968289018 @default.
- W2897726087 hasRelatedWork W2006561075 @default.
- W2897726087 hasRelatedWork W2006964323 @default.
- W2897726087 hasRelatedWork W2013366176 @default.
- W2897726087 hasRelatedWork W2032603793 @default.
- W2897726087 hasRelatedWork W2039393261 @default.
- W2897726087 hasRelatedWork W2045928235 @default.
- W2897726087 hasRelatedWork W2117402884 @default.
- W2897726087 hasRelatedWork W2897726087 @default.
- W2897726087 hasRelatedWork W2966617158 @default.
- W2897726087 isParatext "false" @default.
- W2897726087 isRetracted "false" @default.
- W2897726087 magId "2897726087" @default.
- W2897726087 workType "article" @default.