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• W2897743402 abstract "ObjectiveObesity is classically associated with vitamin D deficiency. The aim of this study was to investigate the association of vitamin D with serum adiponectin concentration and insulin resistance in normal weight and obese individuals.Research methods and proceduresCross-sectional analysis was performed in 76 participants without diabetes (40 obese and 36 normal weight) from a convenience sample of a health counseling center in Belo Horizonte, MG, Brazil. All participants self-reported their skin color as white. Body weight and height were used to calculate body mass index (BMI). Serum insulin, glycemia, vitamin D (25OHD), and adiponectin were evaluated after 12 h fasting. Body fat percentage by electric bioimpedance and waist circumference were analyzed. Pearson's or Spearman's correlation coefficients were calculated. Age- and gender-adjusted associations by multivariate logistic regression were used. Multiplicative interaction terms between 25OHD/adiponectin and BMI were calculated.ResultsParticipant's mean age was 35 ± 9.5 years; 75% were female, and 65.8% were vitamin D insufficient (25OHD < 20 ng/mL). The mean of 25OHD was 28.4 ± 8.6 ng/mL, median of adiponectin was 204 ng/L, and the median of Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) was 2.2. There was no association between 25OHD status, adiponectin, and HOMA-IR in total sample or among obese or normal weight individuals. After adjustments, there was an association between 25OHD insufficiency and body fat percentage (odds ratio = 0.94; confidence interval 95% = 0.88 to 0.99, p = 0.04) in the total sample. BMI did not influence the association between 25OHD and adiponectin.ConclusionThere was a negative association between fat percentage and 25OHD status, but there were no associations between 25OHD, adiponectin, and insulin resistance in this sample. Further studies are needed to understand these associations in other populations." @default.
• W2897743402 created "2018-10-26" @default.
• W2897743402 creator A5051741661 @default.
• W2897743402 creator A5069071484 @default.
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• W2897743402 date "2019-02-01" @default.
• W2897743402 modified "2023-10-18" @default.
• W2897743402 title "Is the association between vitamin D, adiponectin, and insulin resistance present in normal weight or obese? A pilot study" @default.
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• W2897743402 doi "https://doi.org/10.1016/j.yclnex.2018.10.004" @default.
• W2897743402 hasPublicationYear "2019" @default.
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