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- W2897746111 abstract "MicroRNAs (miRNAs) are emerging as important in human embryo implantation, and we present here a review of the literature from a clinical perspective. Implantation involves complex interactions between the blastocyst and endometrium. miRNAs have been shown to be differentially expressed in implanted compared with non-implanted blastocysts and euploid compared with aneuploid blastocysts. Further, miRNAs are differentially expressed in proliferative compared with decidualized endometrium, and in receptive compared with pre-receptive endometrium. miRNAs are also differentially expressed in endometrium of women who failed implantation, and in endometrium of women with recurrent implantation failure. Due to the complexity of miRNA signaling, studies have suffered from inconsistency in reproducibility of results. However, miRNAs show potential as biomarkers in the pursuit of more reliable prediction of embryo implantation." @default.
- W2897746111 created "2018-10-26" @default.
- W2897746111 creator A5002595486 @default.
- W2897746111 creator A5035865772 @default.
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- W2897746111 date "2018-10-12" @default.
- W2897746111 modified "2023-10-18" @default.
- W2897746111 title "The role of microRNAs in human embryo implantation: a review" @default.
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- W2897746111 doi "https://doi.org/10.1007/s10815-018-1326-y" @default.
- W2897746111 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6420523" @default.
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