FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897747725> ?p ?o ?g. }

• W2897747725 abstract "Do embryo culture media used during an IVF/ICSI treatment have an effect on cognitive development of singleton IVF children at 9 years of age? Cognitive development of children born after culture in two different embryo culture media is comparable. Previously, we have shown that the culture medium used in an IVF/ICSI treatment affects birthweight and weight at 2 years of age after alternating assignment to embryo culture in either K-SCICM (Cook) or G1™ Version 3 (Vitrolife). Children with low birthweight are known to have an increased risk for learning disabilities. Data on cognitive development in general of children born after ART are still conflicting, and the only study reporting on the effects of culture medium on cognitive development shows significant differences in cognitive development between two culture medium groups. In this observational cohort follow-up study (MEDIUM-KIDS), parents of all singletons from our abovementioned study were approached after the ninth birthday of their child to participate in an additional follow-up study. Of the 294 eligible children included in the original study, 119 children (70 Vitrolife and 49 Cook) participated in the current study. All follow-up measurements were performed between March 2014 and December 2016. CITO (Dutch Central Institute for Test Development) developed the Dutch pupil monitoring system, which involves nationwide independent, standardized, academic achievement score tests to monitor the child’s school performance twice a year at fixed time points from third grade onward. The tests include language skills (vocabulary and orthography), mathematics and reading capability and comprehension. Results from the tests performed between third and sixth grades, expressed as ability scores, were obtained from the school. To investigate school performance development over the years, we used a mixed effects multilevel model. The least complex model with the best fit was selected to analyze whether culture medium affects cognitive development in our cohort. The study had enough power to detect a difference in ability score that reflects at least one performance category between the two groups. No differences were seen in baseline characteristics between participants and non-participants (both parental and children characteristics). For all domains, the random intercept model was used. All analyses showed comparable results for the two culture medium groups. No significant differences were observed for any of the cognitive development domains, even after correction for potential confounders. Parental level of education was higher in the IVF group (45%) if compared to the national average level of education (35%), which most likely explains the higher CITO scores for the IVF children if compared to the National ability scores. A limitation of the study was its pseudo-randomized design and the relatively low participation rate of 40.5%. This and the number of missing data prevent us from drawing robust causal conclusions. However, as this is the first and therewith oldest cohort of children where culture medium was allocated alternatingly and used in a blinded setting, in the same period, with all other conditions identical this study gives up until now the best available evidence. Our study analyzes the effects of culture medium on school performance of children born after IVF/ICSI in a prospective cohort study. Although further research on long-term academic skills and also on behavior is essential, our results are reassuring and should make parents of children born after IVF/ICSI feel comfortable with their children’s cognitive development. The study was financially supported by the March of Dimes (Grant no. #6-FY13-153). The sponsor of the study had no role in study design, data collection, data analysis, data interpretation or writing of the report. The authors have no conflicts of interest to declare. NTR4220" @default.
• W2897747725 created "2018-10-26" @default.
• W2897747725 creator A5011494200 @default.
• W2897747725 creator A5014281996 @default.
• W2897747725 creator A5030513453 @default.
• W2897747725 creator A5035773850 @default.
• W2897747725 creator A5074145648 @default.
• W2897747725 creator A5084970322 @default.
• W2897747725 creator A5087173002 @default.
• W2897747725 date "2018-01-01" @default.
• W2897747725 modified "2023-10-15" @default.
• W2897747725 title "No effect of IVF culture medium on cognitive development of 9-year-old children" @default.
• W2897747725 cites W1915662031 @default.
• W2897747725 cites W2008894449 @default.
• W2897747725 cites W2041490610 @default.
• W2897747725 cites W2064713310 @default.
• W2897747725 cites W2066302196 @default.
• W2897747725 cites W2125770551 @default.
• W2897747725 cites W2139462280 @default.
• W2897747725 cites W2148734614 @default.
• W2897747725 cites W2153421128 @default.
• W2897747725 cites W2266776456 @default.
• W2897747725 cites W2286927258 @default.
• W2897747725 cites W2304353264 @default.
• W2897747725 cites W2518875896 @default.
• W2897747725 cites W2568319749 @default.
• W2897747725 cites W2611240090 @default.
• W2897747725 cites W2619435510 @default.
• W2897747725 cites W2746186221 @default.
• W2897747725 cites W2884981671 @default.
• W2897747725 cites W4244533362 @default.
• W2897747725 doi "https://doi.org/10.1093/hropen/hoy018" @default.
• W2897747725 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6276664" @default.
• W2897747725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30895259" @default.
• W2897747725 hasPublicationYear "2018" @default.
• W2897747725 type Work @default.
• W2897747725 sameAs 2897747725 @default.
• W2897747725 citedByCount "9" @default.
• W2897747725 countsByYear W28977477252020 @default.
• W2897747725 countsByYear W28977477252021 @default.
• W2897747725 countsByYear W28977477252022 @default.
• W2897747725 countsByYear W28977477252023 @default.
• W2897747725 crossrefType "journal-article" @default.
• W2897747725 hasAuthorship W2897747725A5011494200 @default.
• W2897747725 hasAuthorship W2897747725A5014281996 @default.
• W2897747725 hasAuthorship W2897747725A5030513453 @default.
• W2897747725 hasAuthorship W2897747725A5035773850 @default.
• W2897747725 hasAuthorship W2897747725A5074145648 @default.
• W2897747725 hasAuthorship W2897747725A5084970322 @default.
• W2897747725 hasAuthorship W2897747725A5087173002 @default.
• W2897747725 hasBestOaLocation W28977477251 @default.
• W2897747725 hasConcept C109260823 @default.
• W2897747725 hasConcept C118552586 @default.
• W2897747725 hasConcept C138496976 @default.
• W2897747725 hasConcept C140441792 @default.
• W2897747725 hasConcept C15744967 @default.
• W2897747725 hasConcept C169900460 @default.
• W2897747725 hasConcept C187212893 @default.
• W2897747725 hasConcept C2778073708 @default.
• W2897747725 hasConcept C71924100 @default.
• W2897747725 hasConceptScore W2897747725C109260823 @default.
• W2897747725 hasConceptScore W2897747725C118552586 @default.
• W2897747725 hasConceptScore W2897747725C138496976 @default.
• W2897747725 hasConceptScore W2897747725C140441792 @default.
• W2897747725 hasConceptScore W2897747725C15744967 @default.
• W2897747725 hasConceptScore W2897747725C169900460 @default.
• W2897747725 hasConceptScore W2897747725C187212893 @default.
• W2897747725 hasConceptScore W2897747725C2778073708 @default.
• W2897747725 hasConceptScore W2897747725C71924100 @default.
• W2897747725 hasFunder F4320319906 @default.
• W2897747725 hasIssue "4" @default.
• W2897747725 hasLocation W28977477251 @default.
• W2897747725 hasLocation W28977477252 @default.
• W2897747725 hasLocation W28977477253 @default.
• W2897747725 hasLocation W28977477254 @default.
• W2897747725 hasOpenAccess W2897747725 @default.
• W2897747725 hasPrimaryLocation W28977477251 @default.
• W2897747725 hasRelatedWork W1491288171 @default.
• W2897747725 hasRelatedWork W1537414168 @default.
• W2897747725 hasRelatedWork W1573395472 @default.
• W2897747725 hasRelatedWork W2019522799 @default.
• W2897747725 hasRelatedWork W2023248879 @default.
• W2897747725 hasRelatedWork W2144885025 @default.
• W2897747725 hasRelatedWork W2151437797 @default.
• W2897747725 hasRelatedWork W4284701610 @default.
• W2897747725 hasRelatedWork W584352888 @default.
• W2897747725 hasRelatedWork W594662273 @default.
• W2897747725 hasVolume "2018" @default.
• W2897747725 isParatext "false" @default.
• W2897747725 isRetracted "false" @default.
• W2897747725 magId "2897747725" @default.
• W2897747725 workType "article" @default.