FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897747977> ?p ?o ?g. }

• W2897747977 endingPage "4476" @default.
• W2897747977 startingPage "4467" @default.
• W2897747977 abstract "To describe the international landscape of clinical trials in carbon‐ion radiotherapy (CIRT), the authors reviewed the current status of 63 ongoing clinical trials (median, 47 participants) involving CIRT identified from the US clinicaltrials.gov trial registry and the World Health Organization International Clinical Trials Platform Registry. The objectives were to evaluate the potential for these trials to define the role of this modality in the treatment of specific cancer types and identify the major challenges and opportunities to advance this technology. A significant body of literature suggested the potential for advantageous dose distributions and, in preclinical biologic studies, the enhanced effectiveness for CIRT compared with photons and protons. In addition, clinical evidence from phase I/II trials, although limited, indicated the potential for CIRT to improve cancer outcomes. However, current high‐level phase III randomized clinical trial evidence does not exist. Although there has been an increase in the number of trials investigating CIRT since 2010, and the number of countries and sites offering CIRT is slowly growing, this progress has excluded other countries. Several recommendations are proposed to study this modality to accelerate progress in the field, including: 1) increasing the number of multinational randomized clinical trials, 2) leveraging the existing CIRT facilities to launch larger multinational trials directed at common cancers combined with high‐level quality assurance; and 3) developing more compact and less expensive next‐generation treatment systems integrated with radiobiologic research and preclinical testing." @default.
• W2897747977 created "2018-10-26" @default.
• W2897747977 creator A5017945960 @default.
• W2897747977 creator A5020239394 @default.
• W2897747977 creator A5058580910 @default.
• W2897747977 creator A5076305656 @default.
• W2897747977 creator A5089472018 @default.
• W2897747977 date "2018-10-11" @default.
• W2897747977 modified "2023-10-14" @default.
• W2897747977 title "Clinical trials involving carbon‐ion radiation therapy and the path forward" @default.
• W2897747977 cites W1561111905 @default.
• W2897747977 cites W1941393957 @default.
• W2897747977 cites W1982645808 @default.
• W2897747977 cites W1990514531 @default.
• W2897747977 cites W1993882008 @default.
• W2897747977 cites W2010803333 @default.
• W2897747977 cites W2011197894 @default.
• W2897747977 cites W2012418640 @default.
• W2897747977 cites W2031234109 @default.
• W2897747977 cites W2035002792 @default.
• W2897747977 cites W2044315884 @default.
• W2897747977 cites W2058834009 @default.
• W2897747977 cites W2063531064 @default.
• W2897747977 cites W2075832058 @default.
• W2897747977 cites W2077982938 @default.
• W2897747977 cites W2081294165 @default.
• W2897747977 cites W2085725677 @default.
• W2897747977 cites W2098307421 @default.
• W2897747977 cites W2099874702 @default.
• W2897747977 cites W2100975996 @default.
• W2897747977 cites W2103111058 @default.
• W2897747977 cites W2117205139 @default.
• W2897747977 cites W2132295676 @default.
• W2897747977 cites W2152002544 @default.
• W2897747977 cites W2161771297 @default.
• W2897747977 cites W2166098780 @default.
• W2897747977 cites W2167119115 @default.
• W2897747977 cites W2177112632 @default.
• W2897747977 cites W2236979148 @default.
• W2897747977 cites W2254077791 @default.
• W2897747977 cites W2347061026 @default.
• W2897747977 cites W2407715263 @default.
• W2897747977 cites W2411256141 @default.
• W2897747977 cites W2461718242 @default.
• W2897747977 cites W2472250471 @default.
• W2897747977 cites W2552669727 @default.
• W2897747977 cites W2554738204 @default.
• W2897747977 cites W2559152888 @default.
• W2897747977 cites W2564546025 @default.
• W2897747977 cites W2599868774 @default.
• W2897747977 cites W2600099933 @default.
• W2897747977 cites W2738966944 @default.
• W2897747977 cites W2743350540 @default.
• W2897747977 cites W2749613778 @default.
• W2897747977 cites W2751029436 @default.
• W2897747977 cites W2755063175 @default.
• W2897747977 cites W2760374576 @default.
• W2897747977 cites W2767214600 @default.
• W2897747977 cites W2774997953 @default.
• W2897747977 cites W2775649503 @default.
• W2897747977 cites W2782868025 @default.
• W2897747977 cites W2789780705 @default.
• W2897747977 cites W2789930083 @default.
• W2897747977 cites W2791501358 @default.
• W2897747977 cites W2793592283 @default.
• W2897747977 cites W3149695318 @default.
• W2897747977 cites W74250837 @default.
• W2897747977 doi "https://doi.org/10.1002/cncr.31662" @default.
• W2897747977 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6540799" @default.
• W2897747977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30307603" @default.
• W2897747977 hasPublicationYear "2018" @default.
• W2897747977 type Work @default.
• W2897747977 sameAs 2897747977 @default.
• W2897747977 citedByCount "32" @default.
• W2897747977 countsByYear W28977479772019 @default.
• W2897747977 countsByYear W28977479772020 @default.
• W2897747977 countsByYear W28977479772021 @default.
• W2897747977 countsByYear W28977479772022 @default.
• W2897747977 countsByYear W28977479772023 @default.
• W2897747977 crossrefType "journal-article" @default.
• W2897747977 hasAuthorship W2897747977A5017945960 @default.
• W2897747977 hasAuthorship W2897747977A5020239394 @default.
• W2897747977 hasAuthorship W2897747977A5058580910 @default.
• W2897747977 hasAuthorship W2897747977A5076305656 @default.
• W2897747977 hasAuthorship W2897747977A5089472018 @default.
• W2897747977 hasBestOaLocation W28977479771 @default.
• W2897747977 hasConcept C126322002 @default.
• W2897747977 hasConcept C143998085 @default.
• W2897747977 hasConcept C168563851 @default.
• W2897747977 hasConcept C19527891 @default.
• W2897747977 hasConcept C535046627 @default.
• W2897747977 hasConcept C71924100 @default.
• W2897747977 hasConceptScore W2897747977C126322002 @default.
• W2897747977 hasConceptScore W2897747977C143998085 @default.
• W2897747977 hasConceptScore W2897747977C168563851 @default.
• W2897747977 hasConceptScore W2897747977C19527891 @default.
• W2897747977 hasConceptScore W2897747977C535046627 @default.
• W2897747977 hasConceptScore W2897747977C71924100 @default.

• next