Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897748643> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2897748643 endingPage "1197" @default.
- W2897748643 startingPage "1193" @default.
- W2897748643 abstract "Psoriasis and psoriatic arthritis are common diseases with significant physical and emotional burden. Several biologics are FDA-approved to treat psoriasis and psoriatic arthritis, though some patients remain refractory to, or have lost response to, therapy and/or cannot tolerate the associated risks and side effects. Bimekizumab is a new biologic that inhibits both IL-17A and IL-17F. It is currently in phase III clinical trials. To date, phase II studies show promise in its ability to rapidly resolve symptoms while remaining safe and well-tolerated. Areas covered: This review serves to summarize the literature regarding the use of bimekizumab for psoriasis and psoriatic arthritis. Bimekizumab has undergone phase I and phase II clinical trials with results showing significant disease improvement or resolution, as well as safety and tolerability. Phase III studies are now actively enrolling. Expert opinion: Bimekizumab is a burgeoning biologic offering significant promise through its unique bispecific targeting of both IL-17A and IL-17F. Clinical trials have shown the potential of rapid symptom improvement after treatment with bimekizumab, with some patients seeing improvement after only two weeks. To date, bimekizumab has been shown to be safe and well-tolerated by patients, without any associated significant adverse events." @default.
- W2897748643 created "2018-10-26" @default.
- W2897748643 creator A5049859852 @default.
- W2897748643 creator A5053090736 @default.
- W2897748643 date "2018-10-23" @default.
- W2897748643 modified "2023-09-23" @default.
- W2897748643 title "Bimekizumab for the treatment of psoriatic disease" @default.
- W2897748643 cites W1543896395 @default.
- W2897748643 cites W1986757340 @default.
- W2897748643 cites W2006598510 @default.
- W2897748643 cites W2062383948 @default.
- W2897748643 cites W2070265035 @default.
- W2897748643 cites W2094124191 @default.
- W2897748643 cites W2110264653 @default.
- W2897748643 cites W2115631255 @default.
- W2897748643 cites W2146843653 @default.
- W2897748643 cites W2149168537 @default.
- W2897748643 cites W2345891732 @default.
- W2897748643 cites W2550814440 @default.
- W2897748643 cites W2560549076 @default.
- W2897748643 cites W2592004850 @default.
- W2897748643 cites W2736877074 @default.
- W2897748643 cites W2779290422 @default.
- W2897748643 cites W2783570641 @default.
- W2897748643 cites W2794845062 @default.
- W2897748643 cites W2794921878 @default.
- W2897748643 cites W2810908182 @default.
- W2897748643 cites W2831987875 @default.
- W2897748643 cites W992511358 @default.
- W2897748643 doi "https://doi.org/10.1080/14712598.2018.1538351" @default.
- W2897748643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30332893" @default.
- W2897748643 hasPublicationYear "2018" @default.
- W2897748643 type Work @default.
- W2897748643 sameAs 2897748643 @default.
- W2897748643 citedByCount "15" @default.
- W2897748643 countsByYear W28977486432018 @default.
- W2897748643 countsByYear W28977486432019 @default.
- W2897748643 countsByYear W28977486432020 @default.
- W2897748643 countsByYear W28977486432021 @default.
- W2897748643 countsByYear W28977486432022 @default.
- W2897748643 crossrefType "journal-article" @default.
- W2897748643 hasAuthorship W2897748643A5049859852 @default.
- W2897748643 hasAuthorship W2897748643A5053090736 @default.
- W2897748643 hasConcept C126322002 @default.
- W2897748643 hasConcept C16005928 @default.
- W2897748643 hasConcept C177713679 @default.
- W2897748643 hasConcept C197934379 @default.
- W2897748643 hasConcept C2776260265 @default.
- W2897748643 hasConcept C2778375690 @default.
- W2897748643 hasConcept C2779134260 @default.
- W2897748643 hasConcept C2780564577 @default.
- W2897748643 hasConcept C535046627 @default.
- W2897748643 hasConcept C71924100 @default.
- W2897748643 hasConceptScore W2897748643C126322002 @default.
- W2897748643 hasConceptScore W2897748643C16005928 @default.
- W2897748643 hasConceptScore W2897748643C177713679 @default.
- W2897748643 hasConceptScore W2897748643C197934379 @default.
- W2897748643 hasConceptScore W2897748643C2776260265 @default.
- W2897748643 hasConceptScore W2897748643C2778375690 @default.
- W2897748643 hasConceptScore W2897748643C2779134260 @default.
- W2897748643 hasConceptScore W2897748643C2780564577 @default.
- W2897748643 hasConceptScore W2897748643C535046627 @default.
- W2897748643 hasConceptScore W2897748643C71924100 @default.
- W2897748643 hasIssue "12" @default.
- W2897748643 hasLocation W28977486431 @default.
- W2897748643 hasLocation W28977486432 @default.
- W2897748643 hasOpenAccess W2897748643 @default.
- W2897748643 hasPrimaryLocation W28977486431 @default.
- W2897748643 hasRelatedWork W1789219958 @default.
- W2897748643 hasRelatedWork W2417900408 @default.
- W2897748643 hasRelatedWork W2467573732 @default.
- W2897748643 hasRelatedWork W2601256796 @default.
- W2897748643 hasRelatedWork W2897748643 @default.
- W2897748643 hasRelatedWork W2948178223 @default.
- W2897748643 hasRelatedWork W2985439789 @default.
- W2897748643 hasRelatedWork W3194750073 @default.
- W2897748643 hasRelatedWork W4256724032 @default.
- W2897748643 hasRelatedWork W92320395 @default.
- W2897748643 hasVolume "18" @default.
- W2897748643 isParatext "false" @default.
- W2897748643 isRetracted "false" @default.
- W2897748643 magId "2897748643" @default.
- W2897748643 workType "article" @default.