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- W2897749763 abstract "Osteoarthritis (OA) is a highly prevalent condition, and the hand is the most commonly affected site. Patients with hand OA frequently report symptoms of pain, functional limitations and frustration in undertaking everyday activities. The condition presents clinically with changes to the bone, ligaments, cartilage and synovial tissue, which can be observed using radiography, ultrasonography or MRI. Hand OA is a heterogeneous disorder and is considered to be multifactorial in aetiology. This Review provides an overview of the epidemiology, presentation and burden of hand OA, including an update on hand OA imaging (including the development of novel techniques), disease mechanisms and management. In particular, areas for which new evidence has substantially changed the way we understand, consider and treat hand OA are highlighted. For example, genetic studies, clinical trials and careful prospective imaging studies from the past 5 years are beginning to provide insights into the pathogenesis of hand OA that might uncover new therapeutic targets in the disease. Hand osteoarthritis (OA) is a heterogeneous and prevalent condition involving multiple joints. In this Review, the authors provide an update on the epidemiology, presentation and burden of hand OA, as well as on advances in imaging techniques, disease management and pathogenesis." @default.
- W2897749763 created "2018-10-26" @default.
- W2897749763 creator A5013567204 @default.
- W2897749763 creator A5064224283 @default.
- W2897749763 creator A5086744726 @default.
- W2897749763 creator A5088784640 @default.
- W2897749763 date "2018-10-10" @default.
- W2897749763 modified "2023-10-18" @default.
- W2897749763 title "Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management" @default.
- W2897749763 cites W1486409731 @default.
- W2897749763 cites W1591211846 @default.
- W2897749763 cites W1690382452 @default.
- W2897749763 cites W1838568767 @default.
- W2897749763 cites W1843233424 @default.
- W2897749763 cites W1853247363 @default.
- W2897749763 cites W1916034946 @default.
- W2897749763 cites W1917775169 @default.
- W2897749763 cites W1962572861 @default.
- W2897749763 cites W1963262670 @default.
- W2897749763 cites W1967057044 @default.
- W2897749763 cites W1967717530 @default.
- W2897749763 cites W1968163394 @default.
- W2897749763 cites W1969519907 @default.
- W2897749763 cites W1969655362 @default.
- W2897749763 cites W1969907484 @default.
- W2897749763 cites W1975075132 @default.
- W2897749763 cites W1976917077 @default.
- W2897749763 cites W1980448215 @default.
- W2897749763 cites W1980960079 @default.
- W2897749763 cites W1985614868 @default.
- W2897749763 cites W1986391271 @default.
- W2897749763 cites W1987072881 @default.
- W2897749763 cites W1991950326 @default.
- W2897749763 cites W1994069907 @default.
- W2897749763 cites W1994166068 @default.
- W2897749763 cites W1996379325 @default.
- W2897749763 cites W1996939581 @default.
- W2897749763 cites W2000078736 @default.
- W2897749763 cites W2000862295 @default.
- W2897749763 cites W2004082114 @default.
- W2897749763 cites W2004900129 @default.
- W2897749763 cites W2004919258 @default.
- W2897749763 cites W2012410312 @default.
- W2897749763 cites W2013482409 @default.
- W2897749763 cites W2013904927 @default.
- W2897749763 cites W2014934138 @default.
- W2897749763 cites W2015489914 @default.
- W2897749763 cites W2016259758 @default.
- W2897749763 cites W2016524890 @default.
- W2897749763 cites W2017071862 @default.
- W2897749763 cites W2017744497 @default.
- W2897749763 cites W2020018414 @default.
- W2897749763 cites W2020577994 @default.
- W2897749763 cites W2024105090 @default.
- W2897749763 cites W2025853526 @default.
- W2897749763 cites W2026676331 @default.
- W2897749763 cites W2031027318 @default.
- W2897749763 cites W2031160924 @default.
- W2897749763 cites W2034394772 @default.
- W2897749763 cites W2036491373 @default.
- W2897749763 cites W2037239870 @default.
- W2897749763 cites W2039057022 @default.
- W2897749763 cites W2043753837 @default.
- W2897749763 cites W2046742443 @default.
- W2897749763 cites W2047734268 @default.
- W2897749763 cites W2049209494 @default.
- W2897749763 cites W2050421979 @default.
- W2897749763 cites W2052483663 @default.
- W2897749763 cites W2056100705 @default.
- W2897749763 cites W2057060888 @default.
- W2897749763 cites W2057814697 @default.
- W2897749763 cites W2063014451 @default.
- W2897749763 cites W2063301343 @default.
- W2897749763 cites W2064528414 @default.
- W2897749763 cites W2065291548 @default.
- W2897749763 cites W2070434758 @default.
- W2897749763 cites W2070674441 @default.
- W2897749763 cites W2070875773 @default.
- W2897749763 cites W2073200141 @default.
- W2897749763 cites W2073430626 @default.
- W2897749763 cites W2074477446 @default.
- W2897749763 cites W2075484213 @default.
- W2897749763 cites W2076459183 @default.
- W2897749763 cites W2078399784 @default.
- W2897749763 cites W2080555272 @default.
- W2897749763 cites W2080824635 @default.
- W2897749763 cites W2081123291 @default.
- W2897749763 cites W2082777682 @default.
- W2897749763 cites W2084084388 @default.
- W2897749763 cites W2088453390 @default.
- W2897749763 cites W2089331060 @default.
- W2897749763 cites W2092003581 @default.
- W2897749763 cites W2094059884 @default.
- W2897749763 cites W2095210697 @default.
- W2897749763 cites W2096564678 @default.
- W2897749763 cites W2098003476 @default.
- W2897749763 cites W2098082628 @default.
- W2897749763 cites W2101009799 @default.