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- W2897760072 abstract "We herein report a simple and highly efficient microwave‐assisted, copper‐catalyzed and ligand‐free synthetic method for 2‐substituted 4(3 H )‐quinazolinones as domino reaction. This reaction proceeds via self‐condensation of substrate (2‐bromo/iodo benzamide) in the presence of a strong base and copper catalyst. The substituted quinazolinones were obtained in one‐pot reaction by intramolecular cyclization (condensation) via Ullmann–type intermediate. Both the intermediates and quinazolinones were obtained in good yield and can be further used as building blocks for developing the potential novel drug‐like compounds." @default.
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- W2897760072 date "2018-10-11" @default.
- W2897760072 modified "2023-09-23" @default.
- W2897760072 title "Copper-Catalyzed Self-Condensation of Benzamide: Domino Reactions towards Quinazolinones" @default.
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- W2897760072 doi "https://doi.org/10.1002/ejoc.201800660" @default.
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