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• W2897761483 abstract "We have reported that octacalcium phosphate (OCP) enhances bone repair in critical-sized rat calvaria defects, while OCP is gradually crystallized to apatite structure. Our studies showed that:1.OCP enhances differentiation of osteoblastic cells in two- and three-dimensional conditions.2.OCP enhances osteoclast formation from bone marrow cells (macrophages) in the co-culture with osteoblasts by raising osteoclast-inducing factor (RANKL).3.OCP enhances macrophages migration.4.These cellular responses are brought about associated with the hydrolysis of OCP toward a nonstoichiometric Ca-deficient hydroxyapatite (HA), which is accompanied by physicochemical changes such as inorganic ion exchanges and serum proteins adsorption." @default.
• W2897761483 created "2018-10-26" @default.
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• W2897761483 date "2018-01-01" @default.
• W2897761483 modified "2023-09-25" @default.
• W2897761483 title "Enhancement of Bone Tissue Repair by Octacalcium Phosphate Crystallizing into Hydroxyapatite In Situ" @default.
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• W2897761483 doi "https://doi.org/10.1007/978-981-13-1002-7_20" @default.
• W2897761483 hasPublicationYear "2018" @default.
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