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- W2897779400 abstract "Viruses are intracellular pathogens that cause a vast array of diseases, which are often severe and typified by high morbidity and mortality rates. Viral infections continue to be a global health burden and effective vaccines and therapeutics are constantly sought to prevent and treat these infections. The development of such treatments generally relies on understanding the mechanisms that underpin efficient host antiviral immune responses. This review summarises recent developments in our understanding of antiviral adaptive immunity and in particular, highlights the use of mass spectrometry to elucidate viral antigens and their processing and presentation to T cells and other immune effectors. These processed peptides serve as potential vaccine candidates or may facilitate clinical monitoring, diagnosis and immunotherapy of infectious diseases." @default.
- W2897779400 created "2018-10-26" @default.
- W2897779400 creator A5045304787 @default.
- W2897779400 creator A5087347737 @default.
- W2897779400 date "2018-12-01" @default.
- W2897779400 modified "2023-10-15" @default.
- W2897779400 title "The use of proteomics to understand antiviral immunity" @default.
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- W2897779400 doi "https://doi.org/10.1016/j.semcdb.2017.12.002" @default.
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