Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897787987> ?p ?o ?g. }
- W2897787987 endingPage "357" @default.
- W2897787987 startingPage "347" @default.
- W2897787987 abstract "ABSTRACT The properties of oil-resin of copaiba, Copaifera multijuga are commonly mentioned in the literature, but there are few studies on extracts from its stem bark. We evaluated the antioxidant effects of ethanolic (EE) and ethyl acetate (EA) crude stem bark extracts from copaiba and compared them to rutin in a paracetamol (PCM)-induced oxidative stress model in mice. All test comparisons differed significantly. Hepatic catalase (CAT) and glutathione-S-transferase (GST) activity decreased in the PCM group, and there was an increase of protein carbonyls in the liver, kidney and brain. However, the protein carbonyls decreased in the liver for the PCM + EE group, in the kidneys for the PCM + EA and PCM + Rutin groups, and in the brain for all treatments. Hepatic GSH decreased in the PCM group and increased in the PCM + EE group. The extracts showed a positive effect on ascorbic acid (ASA), since they were able to restore the levels of parameters that had been changed by PCM. There was an increase of ALT and AST activity in the plasma within the PCM group. Even though ALT decreased in the PCM + Rutin, PCM + EE and PCM + EA groups, EE and EA did not have an effect on AST. The strongest antioxidant effect was observed for EE, due to the presence of the phenolic compounds epicatechin and epiafzelechin, as well as the highest concentration of total phenols and an excellent antioxidant potential observed in the DPPH· test." @default.
- W2897787987 created "2018-10-26" @default.
- W2897787987 creator A5015185623 @default.
- W2897787987 creator A5027032484 @default.
- W2897787987 creator A5048238217 @default.
- W2897787987 creator A5054970380 @default.
- W2897787987 creator A5061814345 @default.
- W2897787987 creator A5065813279 @default.
- W2897787987 creator A5070425314 @default.
- W2897787987 date "2018-12-01" @default.
- W2897787987 modified "2023-10-01" @default.
- W2897787987 title "Antioxidant and hepatoprotective effects of ethanolic and ethyl acetate stem bark extracts of Copaifera multijuga (Fabaceae) in mice" @default.
- W2897787987 cites W1527821398 @default.
- W2897787987 cites W1541018201 @default.
- W2897787987 cites W1583489850 @default.
- W2897787987 cites W1590457525 @default.
- W2897787987 cites W1750690213 @default.
- W2897787987 cites W186271392 @default.
- W2897787987 cites W1969273332 @default.
- W2897787987 cites W1970677725 @default.
- W2897787987 cites W1971567525 @default.
- W2897787987 cites W1976950210 @default.
- W2897787987 cites W1976977468 @default.
- W2897787987 cites W1986386392 @default.
- W2897787987 cites W1987778330 @default.
- W2897787987 cites W1991120520 @default.
- W2897787987 cites W1997386193 @default.
- W2897787987 cites W1999814318 @default.
- W2897787987 cites W1999921768 @default.
- W2897787987 cites W2011686154 @default.
- W2897787987 cites W2014558733 @default.
- W2897787987 cites W2015479450 @default.
- W2897787987 cites W2024292291 @default.
- W2897787987 cites W2026330727 @default.
- W2897787987 cites W2028925119 @default.
- W2897787987 cites W2039042657 @default.
- W2897787987 cites W2045737430 @default.
- W2897787987 cites W2052584317 @default.
- W2897787987 cites W2055678464 @default.
- W2897787987 cites W2059565012 @default.
- W2897787987 cites W2063484624 @default.
- W2897787987 cites W2063576996 @default.
- W2897787987 cites W2068227193 @default.
- W2897787987 cites W2072548318 @default.
- W2897787987 cites W2076046120 @default.
- W2897787987 cites W2081229264 @default.
- W2897787987 cites W2090262313 @default.
- W2897787987 cites W2091393386 @default.
- W2897787987 cites W2102552419 @default.
- W2897787987 cites W2103891066 @default.
- W2897787987 cites W2108295799 @default.
- W2897787987 cites W2119351082 @default.
- W2897787987 cites W2124175927 @default.
- W2897787987 cites W2129258621 @default.
- W2897787987 cites W2161655664 @default.
- W2897787987 cites W2164887746 @default.
- W2897787987 cites W2173296077 @default.
- W2897787987 cites W2605784060 @default.
- W2897787987 cites W2768499679 @default.
- W2897787987 cites W4293247451 @default.
- W2897787987 cites W567832868 @default.
- W2897787987 doi "https://doi.org/10.1590/1809-4392201704473" @default.
- W2897787987 hasPublicationYear "2018" @default.
- W2897787987 type Work @default.
- W2897787987 sameAs 2897787987 @default.
- W2897787987 citedByCount "4" @default.
- W2897787987 countsByYear W28977879872019 @default.
- W2897787987 countsByYear W28977879872021 @default.
- W2897787987 countsByYear W28977879872023 @default.
- W2897787987 crossrefType "journal-article" @default.
- W2897787987 hasAuthorship W2897787987A5015185623 @default.
- W2897787987 hasAuthorship W2897787987A5027032484 @default.
- W2897787987 hasAuthorship W2897787987A5048238217 @default.
- W2897787987 hasAuthorship W2897787987A5054970380 @default.
- W2897787987 hasAuthorship W2897787987A5061814345 @default.
- W2897787987 hasAuthorship W2897787987A5065813279 @default.
- W2897787987 hasAuthorship W2897787987A5070425314 @default.
- W2897787987 hasBestOaLocation W28977879871 @default.
- W2897787987 hasConcept C133446333 @default.
- W2897787987 hasConcept C181199279 @default.
- W2897787987 hasConcept C185592680 @default.
- W2897787987 hasConcept C18903297 @default.
- W2897787987 hasConcept C2775963812 @default.
- W2897787987 hasConcept C2776151105 @default.
- W2897787987 hasConcept C2778004101 @default.
- W2897787987 hasConcept C2778979269 @default.
- W2897787987 hasConcept C2779858419 @default.
- W2897787987 hasConcept C2781401929 @default.
- W2897787987 hasConcept C2986274086 @default.
- W2897787987 hasConcept C31903555 @default.
- W2897787987 hasConcept C538909803 @default.
- W2897787987 hasConcept C55493867 @default.
- W2897787987 hasConcept C556039675 @default.
- W2897787987 hasConcept C71924100 @default.
- W2897787987 hasConcept C86803240 @default.
- W2897787987 hasConceptScore W2897787987C133446333 @default.
- W2897787987 hasConceptScore W2897787987C181199279 @default.
- W2897787987 hasConceptScore W2897787987C185592680 @default.