Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897814338> ?p ?o ?g. }
- W2897814338 endingPage "873" @default.
- W2897814338 startingPage "841" @default.
- W2897814338 abstract "In this article we examine the history of the production of microarray technologies and their role in constructing and operationalizing views of human genetic difference in contemporary genomics. Rather than the turn to difference emerging as a post-Human Genome Project (HGP) phenomenon, interest in individual and group differences was a central, motivating concept in human genetics throughout the twentieth century. This interest was entwined with efforts to develop polymorphic genetic markers for studying human traits and diseases. We trace the technological, methodological and conceptual strategies in the late twentieth century that established single nucleotide polymorphisms (SNPs) as key focal points for locating difference in the genome. By embedding SNPs in microarrays, researchers created a technology that they used to catalog and assess human genetic variation. In the process of making genetic markers and array-based technologies to track variation, scientists also made commitments to ways of describing, cataloging and knowing human genetic differences that refracted difference through a continental geographic lens. We show how difference came to matter in both senses of the term: difference was made salient to, and inscribed on, genetic matter(s), as a result of the decisions, assessments and choices of collaborative and hybrid research collectives in medical genomics research." @default.
- W2897814338 created "2018-10-26" @default.
- W2897814338 creator A5062394753 @default.
- W2897814338 creator A5078979932 @default.
- W2897814338 date "2018-10-18" @default.
- W2897814338 modified "2023-10-14" @default.
- W2897814338 title "Variations on a Chip: Technologies of Difference in Human Genetics Research" @default.
- W2897814338 cites W1487785114 @default.
- W2897814338 cites W1508985588 @default.
- W2897814338 cites W1528109151 @default.
- W2897814338 cites W1542836032 @default.
- W2897814338 cites W1545958975 @default.
- W2897814338 cites W1803375514 @default.
- W2897814338 cites W1968828650 @default.
- W2897814338 cites W196951419 @default.
- W2897814338 cites W1970156673 @default.
- W2897814338 cites W1971541955 @default.
- W2897814338 cites W1975188059 @default.
- W2897814338 cites W1996473312 @default.
- W2897814338 cites W1997494071 @default.
- W2897814338 cites W2000334423 @default.
- W2897814338 cites W2024083614 @default.
- W2897814338 cites W2024381852 @default.
- W2897814338 cites W2025306791 @default.
- W2897814338 cites W2028332147 @default.
- W2897814338 cites W2029441111 @default.
- W2897814338 cites W2032140756 @default.
- W2897814338 cites W2042103448 @default.
- W2897814338 cites W2044692125 @default.
- W2897814338 cites W2046056761 @default.
- W2897814338 cites W2048755332 @default.
- W2897814338 cites W2053964427 @default.
- W2897814338 cites W2060647262 @default.
- W2897814338 cites W2061008984 @default.
- W2897814338 cites W2063124307 @default.
- W2897814338 cites W2063790852 @default.
- W2897814338 cites W2065218625 @default.
- W2897814338 cites W2074754379 @default.
- W2897814338 cites W2079501979 @default.
- W2897814338 cites W2081067541 @default.
- W2897814338 cites W2088893805 @default.
- W2897814338 cites W2089579563 @default.
- W2897814338 cites W2091143313 @default.
- W2897814338 cites W2096114751 @default.
- W2897814338 cites W2102008968 @default.
- W2897814338 cites W2104549677 @default.
- W2897814338 cites W2105025553 @default.
- W2897814338 cites W2106601223 @default.
- W2897814338 cites W2107121611 @default.
- W2897814338 cites W2107889007 @default.
- W2897814338 cites W2107916366 @default.
- W2897814338 cites W2113784410 @default.
- W2897814338 cites W2118864476 @default.
- W2897814338 cites W2124277514 @default.
- W2897814338 cites W2130997200 @default.
- W2897814338 cites W2134783591 @default.
- W2897814338 cites W2135732313 @default.
- W2897814338 cites W2137743001 @default.
- W2897814338 cites W2139210122 @default.
- W2897814338 cites W2145307001 @default.
- W2897814338 cites W2148636100 @default.
- W2897814338 cites W2152664025 @default.
- W2897814338 cites W2156247751 @default.
- W2897814338 cites W2159511216 @default.
- W2897814338 cites W2159797388 @default.
- W2897814338 cites W2160782760 @default.
- W2897814338 cites W2168532852 @default.
- W2897814338 cites W2460337102 @default.
- W2897814338 cites W2471779958 @default.
- W2897814338 cites W2475146492 @default.
- W2897814338 cites W2563392956 @default.
- W2897814338 cites W4211135059 @default.
- W2897814338 cites W4250844131 @default.
- W2897814338 cites W4254753097 @default.
- W2897814338 cites W53016874 @default.
- W2897814338 doi "https://doi.org/10.1007/s10739-018-9543-x" @default.
- W2897814338 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30338423" @default.
- W2897814338 hasPublicationYear "2018" @default.
- W2897814338 type Work @default.
- W2897814338 sameAs 2897814338 @default.
- W2897814338 citedByCount "9" @default.
- W2897814338 countsByYear W28978143382019 @default.
- W2897814338 countsByYear W28978143382020 @default.
- W2897814338 countsByYear W28978143382021 @default.
- W2897814338 countsByYear W28978143382022 @default.
- W2897814338 countsByYear W28978143382023 @default.
- W2897814338 crossrefType "journal-article" @default.
- W2897814338 hasAuthorship W2897814338A5062394753 @default.
- W2897814338 hasAuthorship W2897814338A5078979932 @default.
- W2897814338 hasBestOaLocation W28978143381 @default.
- W2897814338 hasConcept C104317684 @default.
- W2897814338 hasConcept C141231307 @default.
- W2897814338 hasConcept C189206191 @default.
- W2897814338 hasConcept C197077220 @default.
- W2897814338 hasConcept C2522767166 @default.
- W2897814338 hasConcept C40583040 @default.
- W2897814338 hasConcept C41008148 @default.
- W2897814338 hasConcept C54355233 @default.