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- W2897820933 abstract "Introduction: Mechanical endovascular reperfusion (MER) is considered definitive treatment for patients presenting with acute ischemic stroke secondary to large-vessel occlusion. Outcome is dependent upon rapid initiation of MER, and there is concern that any antecedent delay, including time needed to identify the stroke and initiate intravenous tissue plasminogen activator (IV tPA), may adversely affect the time to definitive MER therapy. We analyzed the door-to-recanalization times for patients with large-vessel occlusion who underwent MER at our institution, comparing those who received IV tPA at our institution versus those who presented as a drip-and-ship transfer from an outside hospital. We hypothesized that door-to-recanalization times would be shorter for the transferred patients since they had been pre-identified as an acute ischemic stroke and had already received IV tPA. Methods: This was a retrospective data analysis from a single Joint-Commission certified Comprehensive Stroke Center. All patients who presented to our institution between January 2016 - November 2016 and received both IV tPA and MER were included. Comparison was made between those who received IV tPA at our institution versus an outside hospital. Door-to-recanalization metrics captured in our local stroke-alert registry were analyzed. Results: Twenty patients received both IV tPA and MER during the time period evaluated. Comparison between patients who received both interventions at our institution versus those who received IV tPA prior to transfer demonstrated no statistically significant difference in total door-to-recanalization times (t-test: two-samples with unequal variances, p = 0.05). Conclusion: At our single tertiary stroke center, the time required to identify a large-vessel stroke and administer IV t-PA does not add appreciable delay to recanalization by MER." @default.
- W2897820933 created "2018-10-26" @default.
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- W2897820933 date "2018-01-22" @default.
- W2897820933 modified "2023-09-25" @default.
- W2897820933 title "Abstract TP295: Administration of Intravenous Tissue Plasminogen Activator Does Not Prolong Door-to-Recanalization Time in Acute Large-Vessel Strokes" @default.
- W2897820933 doi "https://doi.org/10.1161/str.49.suppl_1.tp295" @default.
- W2897820933 hasPublicationYear "2018" @default.
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