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• W2897828647 endingPage "242" @default.
• W2897828647 startingPage "227" @default.
• W2897828647 abstract "The evolutionary origins of the three major families of chemoreceptors in arthropods—the odorant receptor (OR), gustatory receptor (GR), and ionotropic receptor (IR) families—occurred at the base of the Insecta, Animalia, and Protostomia, respectively. Comparison of receptor family sizes across arthropods reveals a generally positive correlation with their widely disparate complexity of chemical ecology. Closely related species reveal the ongoing processes of gene family evolution, including gene duplication, divergence, pseudogenization, and loss, that mediate these larger patterns. Sets of paralogous receptors within species reveal positive selection on amino acids in regions likely to contribute to ligand binding and specificity. Ligands of many ORs and some GRs and IRs have been identified; however, ligand identification for many more chemoreceptors is needed, as are structures for the OR/GR superfamily, to improve our understanding of the molecular evolution of these ecologically important receptors in arthropods." @default.
• W2897828647 created "2018-10-26" @default.
• W2897828647 creator A5049466852 @default.
• W2897828647 date "2019-01-07" @default.
• W2897828647 modified "2023-10-11" @default.
• W2897828647 title "Molecular Evolution of the Major Arthropod Chemoreceptor Gene Families" @default.
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