FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897834846> ?p ?o ?g. }

• W2897834846 endingPage "39" @default.
• W2897834846 startingPage "32" @default.
• W2897834846 abstract "Breathing disorders are commonly observed in association with obesity. Here we tested whether high-fat diet (HFD) impairs the chemoreflex ventilatory response. Male Holtzman rats (300-320 g) were fed with standard chow diet (SD) or HFD for 12 weeks. Then, tidal volume (VT), respiratory frequency (fR) and pulmonary ventilation (VE) were determined in conscious rats during basal condition, hypercapnia (7% or 10% CO2) or hypoxia (7% O2). The mean arterial pressure (MAP), heart rate (HR) and baroreflex sensitivity were also evaluated in conscious rats. A group of anesthetized rats was used for the measurements of the activity of inspiratory (diaphragm) and expiratory (abdominal) muscles under the same gas conditions. Baseline fR, VT and VE were similar between SD and HFD rats. During hypercapnia, the increase of fR was exacerbated in conscious HFD rats (60 ± 3, vs. SD: 47 ± 3 Δ breaths.min-1, P < 0.05). In anesthetized rats, hypercapnia strongly increased abdominal muscle activity in HFD group (238 ± 27, vs. basal condition: 100 ± 0.3%; P < 0.05), without significant change in SD group (129 ± 2.1, vs. basal condition: 100 ± 0.8%; P = 0.34). The ventilatory responses to hypoxia were similar between groups. In conscious HFD rats, MAP and HR were elevated and the baroreflex function was impaired (P < 0.05). These data demonstrated that 12 weeks of HFD exaggerate the ventilatory response activated by hypercapnia. The mechanisms involved in these responses need more investigation in future studies." @default.
• W2897834846 created "2018-10-26" @default.
• W2897834846 creator A5013170495 @default.
• W2897834846 creator A5034555373 @default.
• W2897834846 creator A5039714731 @default.
• W2897834846 creator A5041798007 @default.
• W2897834846 creator A5071094689 @default.
• W2897834846 creator A5081476636 @default.
• W2897834846 creator A5081612625 @default.
• W2897834846 date "2018-12-01" @default.
• W2897834846 modified "2023-10-14" @default.
• W2897834846 title "High-fat diet increases respiratory frequency and abdominal expiratory motor activity during hypercapnia" @default.
• W2897834846 cites W1510912246 @default.
• W2897834846 cites W1969051028 @default.
• W2897834846 cites W1972491686 @default.
• W2897834846 cites W1983082230 @default.
• W2897834846 cites W1983528022 @default.
• W2897834846 cites W1984366759 @default.
• W2897834846 cites W1988600624 @default.
• W2897834846 cites W1989793378 @default.
• W2897834846 cites W1991334358 @default.
• W2897834846 cites W1998627270 @default.
• W2897834846 cites W2001941370 @default.
• W2897834846 cites W2006385173 @default.
• W2897834846 cites W2006884460 @default.
• W2897834846 cites W2025517143 @default.
• W2897834846 cites W2028874421 @default.
• W2897834846 cites W2029139076 @default.
• W2897834846 cites W2041558739 @default.
• W2897834846 cites W2041691732 @default.
• W2897834846 cites W2047567570 @default.
• W2897834846 cites W2052083646 @default.
• W2897834846 cites W2054784843 @default.
• W2897834846 cites W2055603755 @default.
• W2897834846 cites W2056335561 @default.
• W2897834846 cites W2076422538 @default.
• W2897834846 cites W2099319340 @default.
• W2897834846 cites W2110756853 @default.
• W2897834846 cites W2111772099 @default.
• W2897834846 cites W2121292496 @default.
• W2897834846 cites W2121351994 @default.
• W2897834846 cites W2124334610 @default.
• W2897834846 cites W2124471616 @default.
• W2897834846 cites W2124865189 @default.
• W2897834846 cites W2125893767 @default.
• W2897834846 cites W2126852048 @default.
• W2897834846 cites W2138960012 @default.
• W2897834846 cites W2139009524 @default.
• W2897834846 cites W2147726979 @default.
• W2897834846 cites W2157851792 @default.
• W2897834846 cites W2161032173 @default.
• W2897834846 cites W2171086193 @default.
• W2897834846 cites W2227777481 @default.
• W2897834846 cites W2273004187 @default.
• W2897834846 cites W2330087098 @default.
• W2897834846 cites W2523509417 @default.
• W2897834846 cites W2609188715 @default.
• W2897834846 cites W2777047268 @default.
• W2897834846 doi "https://doi.org/10.1016/j.resp.2018.10.003" @default.
• W2897834846 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6317333" @default.
• W2897834846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30308245" @default.
• W2897834846 hasPublicationYear "2018" @default.
• W2897834846 type Work @default.
• W2897834846 sameAs 2897834846 @default.
• W2897834846 citedByCount "10" @default.
• W2897834846 countsByYear W28978348462018 @default.
• W2897834846 countsByYear W28978348462019 @default.
• W2897834846 countsByYear W28978348462020 @default.
• W2897834846 countsByYear W28978348462021 @default.
• W2897834846 countsByYear W28978348462022 @default.
• W2897834846 crossrefType "journal-article" @default.
• W2897834846 hasAuthorship W2897834846A5013170495 @default.
• W2897834846 hasAuthorship W2897834846A5034555373 @default.
• W2897834846 hasAuthorship W2897834846A5039714731 @default.
• W2897834846 hasAuthorship W2897834846A5041798007 @default.
• W2897834846 hasAuthorship W2897834846A5071094689 @default.
• W2897834846 hasAuthorship W2897834846A5081476636 @default.
• W2897834846 hasAuthorship W2897834846A5081612625 @default.
• W2897834846 hasBestOaLocation W28978348461 @default.
• W2897834846 hasConcept C126322002 @default.
• W2897834846 hasConcept C127413603 @default.
• W2897834846 hasConcept C134018914 @default.
• W2897834846 hasConcept C178790620 @default.
• W2897834846 hasConcept C185592680 @default.
• W2897834846 hasConcept C191237925 @default.
• W2897834846 hasConcept C200457457 @default.
• W2897834846 hasConcept C2777037550 @default.
• W2897834846 hasConcept C2777257755 @default.
• W2897834846 hasConcept C2777953023 @default.
• W2897834846 hasConcept C2778024521 @default.
• W2897834846 hasConcept C2779306644 @default.
• W2897834846 hasConcept C2780157289 @default.
• W2897834846 hasConcept C42219234 @default.
• W2897834846 hasConcept C534529494 @default.
• W2897834846 hasConcept C540031477 @default.
• W2897834846 hasConcept C71924100 @default.
• W2897834846 hasConcept C7836513 @default.
• W2897834846 hasConcept C78519656 @default.

• next