FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897839407> ?p ?o ?g. }

• W2897839407 abstract "Abstract Aedes albopictus ( Ae. albopictus ) is an important vector of arboviruses such as Dengue virus (DENV), Chikungunya virus (CHIKV), and Zika virus (ZIKV). Long noncoding RNA (lncRNAs) have been identified in other vectors including Aedes aegypti and Anopheles mosquitoes, few of which have been implicated in immunity and viral replication. To identify lncRNAs with potential biological functions in Ae. albopictus , we performed RNA-seq on Ae. albopictus cells infected with DENV and ZIKV, and analyzed them together with public datasets. We identified a total of 23,899 transcripts, 16,089 were intergenic while 3,126 and 4,183 of them were antisense and intronic to annotated genes respectively. Ae. albopictus lncRNAs shared many of the characteristics with their invertebrate and vertebrate counterparts, such as low expression, low GC content, short in length, and low conservation even among closely related species. Compared to protein-coding genes, lncRNAs exhibited higher tendency to be expressed in a stage-specific manner. Besides, expression of lncRNAs and nearest protein-coding genes tended to be correlated, especially for the gene pairs within 1kb from each other. We also discovered that Ae. albopictus lncRNAs have the potential to act as precursors for miRNA and piRNAs, both of which have been implicated in antiviral defense in Aedes mosquito. Upon flavivirus infection, lncRNAs were observed to be differentially expressed, which possibly indicates the involvement of lncRNAs in the host-antiviral defense. Our study provides the first systematic identification of lncRNAs in Ae. albopictus , hence, offering a foundation for future studies of lncRNA functions." @default.
• W2897839407 created "2018-10-26" @default.
• W2897839407 creator A5022805702 @default.
• W2897839407 creator A5031882943 @default.
• W2897839407 creator A5049076363 @default.
• W2897839407 date "2018-10-22" @default.
• W2897839407 modified "2023-10-14" @default.
• W2897839407 title "Identification and characterization of Aedes albopictus long noncoding RNAs provides insights into their roles in development and flavivirus infection" @default.
• W2897839407 cites W1602695373 @default.
• W2897839407 cites W1908905777 @default.
• W2897839407 cites W1971776032 @default.
• W2897839407 cites W1976342457 @default.
• W2897839407 cites W1981509058 @default.
• W2897839407 cites W1995618392 @default.
• W2897839407 cites W2011657487 @default.
• W2897839407 cites W2046261273 @default.
• W2897839407 cites W2048194168 @default.
• W2897839407 cites W2051911149 @default.
• W2897839407 cites W2058970225 @default.
• W2897839407 cites W2061419819 @default.
• W2897839407 cites W2061548680 @default.
• W2897839407 cites W2065669787 @default.
• W2897839407 cites W2097075232 @default.
• W2897839407 cites W2102278945 @default.
• W2897839407 cites W2104005232 @default.
• W2897839407 cites W2114104545 @default.
• W2897839407 cites W2118420574 @default.
• W2897839407 cites W2120597842 @default.
• W2897839407 cites W2125222853 @default.
• W2897839407 cites W2125346459 @default.
• W2897839407 cites W2129078669 @default.
• W2897839407 cites W2130305733 @default.
• W2897839407 cites W2131271579 @default.
• W2897839407 cites W2133465414 @default.
• W2897839407 cites W2141458291 @default.
• W2897839407 cites W2152327613 @default.
• W2897839407 cites W2153268494 @default.
• W2897839407 cites W2156880688 @default.
• W2897839407 cites W2157322693 @default.
• W2897839407 cites W2158217645 @default.
• W2897839407 cites W2160333540 @default.
• W2897839407 cites W2161243071 @default.
• W2897839407 cites W2239966924 @default.
• W2897839407 cites W2281309807 @default.
• W2897839407 cites W2291352087 @default.
• W2897839407 cites W2313500346 @default.
• W2897839407 cites W2524171444 @default.
• W2897839407 cites W2536820283 @default.
• W2897839407 cites W2540381357 @default.
• W2897839407 cites W2562912595 @default.
• W2897839407 cites W2571283472 @default.
• W2897839407 cites W2584207706 @default.
• W2897839407 cites W2592811885 @default.
• W2897839407 cites W2615786037 @default.
• W2897839407 cites W2730983731 @default.
• W2897839407 cites W2742823518 @default.
• W2897839407 cites W2749853308 @default.
• W2897839407 cites W2782871299 @default.
• W2897839407 cites W2805895807 @default.
• W2897839407 cites W2886890299 @default.
• W2897839407 cites W2951741683 @default.
• W2897839407 cites W3098374708 @default.
• W2897839407 doi "https://doi.org/10.1101/448852" @default.
• W2897839407 hasPublicationYear "2018" @default.
• W2897839407 type Work @default.
• W2897839407 sameAs 2897839407 @default.
• W2897839407 citedByCount "0" @default.
• W2897839407 crossrefType "posted-content" @default.
• W2897839407 hasAuthorship W2897839407A5022805702 @default.
• W2897839407 hasAuthorship W2897839407A5031882943 @default.
• W2897839407 hasAuthorship W2897839407A5049076363 @default.
• W2897839407 hasBestOaLocation W28978394071 @default.
• W2897839407 hasConcept C104317684 @default.
• W2897839407 hasConcept C159047783 @default.
• W2897839407 hasConcept C173758957 @default.
• W2897839407 hasConcept C18903297 @default.
• W2897839407 hasConcept C2522874641 @default.
• W2897839407 hasConcept C2776853612 @default.
• W2897839407 hasConcept C2777053367 @default.
• W2897839407 hasConcept C2777775583 @default.
• W2897839407 hasConcept C2779635636 @default.
• W2897839407 hasConcept C2780568436 @default.
• W2897839407 hasConcept C2781273456 @default.
• W2897839407 hasConcept C40767141 @default.
• W2897839407 hasConcept C533803919 @default.
• W2897839407 hasConcept C54355233 @default.
• W2897839407 hasConcept C67705224 @default.
• W2897839407 hasConcept C86803240 @default.
• W2897839407 hasConcept C92087593 @default.
• W2897839407 hasConceptScore W2897839407C104317684 @default.
• W2897839407 hasConceptScore W2897839407C159047783 @default.
• W2897839407 hasConceptScore W2897839407C173758957 @default.
• W2897839407 hasConceptScore W2897839407C18903297 @default.
• W2897839407 hasConceptScore W2897839407C2522874641 @default.
• W2897839407 hasConceptScore W2897839407C2776853612 @default.
• W2897839407 hasConceptScore W2897839407C2777053367 @default.
• W2897839407 hasConceptScore W2897839407C2777775583 @default.
• W2897839407 hasConceptScore W2897839407C2779635636 @default.
• W2897839407 hasConceptScore W2897839407C2780568436 @default.
• W2897839407 hasConceptScore W2897839407C2781273456 @default.

• next