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• W2897841348 abstract "The Central Nervous System is a highly complex network composed of various cell types, each one with different subpopulations. Each cell type has distinct roles for the functional operation of circuits, and ultimately, for brain physiology in general. Since the absolute number of each cell type is considered a proxy of its functional complexity, one approach to better understand how the brain works is to unravel its absolute cellularity and the quantitative relations between cell populations; in other words, how one population of cells is quantitatively structured, in relation to another. Oligodendrocytes are one of these cell types – mainly, they provide electric insulation to axons, optimizing action potential conduction. Their function has recently been revisited and their role extended, one example being their capability of providing trophic support to long axons. To determine the absolute cellularity of oligodendroglia, we have developed a protocol of oligodendrocyte quantification using the isotropic fractionator. We report a detailed assessment of specificity and universality of the oligodendrocyte transcription factor 2 (Olig2), through systematic confocal analyses of the C57BL/6 mouse brain. In addition, we have determined the absolute number (17.4 million) and proportion (about 20%) of this cell type in the brain (and in different brain regions), and tested if this population, at the intraspecific level, scales with the number of neurons in an allometric-based approach. Considering these numbers, oligodendrocytes proved to be the most numerous of glial cells in the mouse brain." @default.
• W2897841348 created "2018-10-26" @default.
• W2897841348 creator A5008295165 @default.
• W2897841348 creator A5011497788 @default.
• W2897841348 creator A5041094104 @default.
• W2897841348 creator A5051716560 @default.
• W2897841348 date "2018-10-30" @default.
• W2897841348 modified "2023-10-17" @default.
• W2897841348 title "The Absolute Number of Oligodendrocytes in the Adult Mouse Brain" @default.
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• W2897841348 cites W1922804481 @default.
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• W2897841348 cites W1967937854 @default.
• W2897841348 cites W1972283875 @default.
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• W2897841348 doi "https://doi.org/10.3389/fnana.2018.00090" @default.
• W2897841348 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6218541" @default.
• W2897841348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30425626" @default.
• W2897841348 hasPublicationYear "2018" @default.
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