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- W2897842561 abstract "Background Alternate day fasting (ADF) with a low-fat (LF) background diet facilitates weight loss and is cardio-protective in obese individuals. Whether these beneficial effects can be reproduced by a high-fat (HF) ADF diet is not known. Objective This study examined the effects of an ADF-HF versus ADF-LF diet on body weight, body composition and cardiovascular disease (CVD) risk in obese humans. Methods Thirty-three obese subjects were randomized to an ADF-HF or ADF-LF diet for 10 weeks. All food was provided during the study. Results Body weight was reduced (P < 0.0001) by 4.9%, and 4.2% in the ADF-HF and ADFLF group, respectively. Waist circumference decreased (P < 0.0001) by 7.6%, and 7.5% in the ADF-HF and ADF-LF groups, respectively. LDL cholesterol was reduced (P < 0.0001) by 19.1%, and 24.8%, whereas triglycerides were lowered (P = .0001) by 13.3% and 14.3%, in the ADF-HF and ADF-LF group, respectively. There were no changes in blood pressure or heart rate. Conclusion These findings suggest that an ADF-HF diet is equally as effective as an ADF-LF diet in helping obese subjects lose weight and improve CVD risk factors." @default.
- W2897842561 created "2018-10-26" @default.
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- W2897842561 date "2012-04-01" @default.
- W2897842561 modified "2023-09-27" @default.
- W2897842561 title "Alternate day fasting (ADF) with a high fat background diet produces similar weight loss and cardio‐protection when compared to ADF with a low fat background diet" @default.
- W2897842561 doi "https://doi.org/10.1096/fasebj.26.1_supplement.lb339" @default.
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