FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897843357> ?p ?o ?g. }

• W2897843357 endingPage "e368" @default.
• W2897843357 startingPage "e357" @default.
• W2897843357 abstract "Objectives The objective of this registry was to study the safety of prehospital initiation of ticagrelor compared with clopidogrel. Background Ticagrelor has replaced clopidogrel in many hospitals as the routinely used antiplatelet drug in patients with ST-segment elevation myocardial infarction (STEMI). Nevertheless, in the PLATelet inhibition and patient Outcomes (PLATO) trial, ticagrelor was associated with an increase in non-CABG (non–coronary artery bypass grafting)-related major bleeding. Data comparing the safety of ticagrelor and clopidogrel after prehospital initiation of treatment are not available. Methods A retrospective, multicenter registry was performed. Selection criteria were the administration of a prehospital loading dose of ticagrelor or clopidogrel according to the ambulance STEMI treatment protocol and the presentation to a percutaneous coronary intervention–capable hospital in our region between January 2011 and December 2012. Follow-up was performed using the electronic patient files for the time period between the antiplatelet loading dose and hospital discharge. The data were analyzed using a primary bleeding end point (any bleeding) and a secondary thrombotic end point (all-cause mortality, spontaneous myocardial infarction, definite stent thrombosis, stroke, or transient ischemic attack). Results Data of 304 clopidogrel-treated and 309 ticagrelor-treated patients were available for analysis. No significant difference in bleeding rate was observed between both groups, using univariate (17.8 vs. 20.1%; p = 0.47; odds ratio, 1.16 [95% confidence interval, 0.78–1.74]) and multivariate (p = 0.42) analysis. Also for the secondary thrombotic end point (6.3 vs. 4.9%, p = 0.45), no significant differences were observed. Conclusion In this real-world registry, no significant differences in bleeding or thrombotic event rate were found between ticagrelor and clopidogrel after prehospital initiation of treatment." @default.
• W2897843357 created "2018-10-26" @default.
• W2897843357 creator A5003044560 @default.
• W2897843357 creator A5007123733 @default.
• W2897843357 creator A5017351131 @default.
• W2897843357 creator A5027244910 @default.
• W2897843357 creator A5044824813 @default.
• W2897843357 creator A5047065467 @default.
• W2897843357 creator A5064344076 @default.
• W2897843357 creator A5067557350 @default.
• W2897843357 creator A5081365297 @default.
• W2897843357 creator A5087292466 @default.
• W2897843357 date "2018-10-01" @default.
• W2897843357 modified "2023-10-18" @default.
• W2897843357 title "Safety of Ticagrelor Compared to Clopidogrel after Prehospital Initiation of Treatment" @default.
• W2897843357 cites W101302537 @default.
• W2897843357 cites W1582447064 @default.
• W2897843357 cites W196615512 @default.
• W2897843357 cites W1983438373 @default.
• W2897843357 cites W1984561342 @default.
• W2897843357 cites W1988212011 @default.
• W2897843357 cites W1991216795 @default.
• W2897843357 cites W2001688139 @default.
• W2897843357 cites W2039881470 @default.
• W2897843357 cites W2058217708 @default.
• W2897843357 cites W2084673482 @default.
• W2897843357 cites W2087150869 @default.
• W2897843357 cites W2107797912 @default.
• W2897843357 cites W2111440117 @default.
• W2897843357 cites W2112165747 @default.
• W2897843357 cites W2112380741 @default.
• W2897843357 cites W2119541630 @default.
• W2897843357 cites W2122776876 @default.
• W2897843357 cites W2122779695 @default.
• W2897843357 cites W2125043491 @default.
• W2897843357 cites W2136085304 @default.
• W2897843357 cites W2139834809 @default.
• W2897843357 cites W2140501627 @default.
• W2897843357 cites W2142825093 @default.
• W2897843357 cites W2143178796 @default.
• W2897843357 cites W2144796822 @default.
• W2897843357 cites W2148678963 @default.
• W2897843357 cites W2161055506 @default.
• W2897843357 cites W2166950143 @default.
• W2897843357 cites W2169387542 @default.
• W2897843357 cites W2170770879 @default.
• W2897843357 cites W2293758496 @default.
• W2897843357 cites W2310922876 @default.
• W2897843357 cites W2402119165 @default.
• W2897843357 cites W2605250584 @default.
• W2897843357 cites W2622781434 @default.
• W2897843357 cites W2754054868 @default.
• W2897843357 cites W2767025729 @default.
• W2897843357 cites W2803744020 @default.
• W2897843357 cites W4205653014 @default.
• W2897843357 cites W4211104669 @default.
• W2897843357 doi "https://doi.org/10.1055/s-0038-1673389" @default.
• W2897843357 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6524899" @default.
• W2897843357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31249961" @default.
• W2897843357 hasPublicationYear "2018" @default.
• W2897843357 type Work @default.
• W2897843357 sameAs 2897843357 @default.
• W2897843357 citedByCount "3" @default.
• W2897843357 countsByYear W28978433572020 @default.
• W2897843357 countsByYear W28978433572022 @default.
• W2897843357 crossrefType "journal-article" @default.
• W2897843357 hasAuthorship W2897843357A5003044560 @default.
• W2897843357 hasAuthorship W2897843357A5007123733 @default.
• W2897843357 hasAuthorship W2897843357A5017351131 @default.
• W2897843357 hasAuthorship W2897843357A5027244910 @default.
• W2897843357 hasAuthorship W2897843357A5044824813 @default.
• W2897843357 hasAuthorship W2897843357A5047065467 @default.
• W2897843357 hasAuthorship W2897843357A5064344076 @default.
• W2897843357 hasAuthorship W2897843357A5067557350 @default.
• W2897843357 hasAuthorship W2897843357A5081365297 @default.
• W2897843357 hasAuthorship W2897843357A5087292466 @default.
• W2897843357 hasBestOaLocation W28978433571 @default.
• W2897843357 hasConcept C126322002 @default.
• W2897843357 hasConcept C127413603 @default.
• W2897843357 hasConcept C156957248 @default.
• W2897843357 hasConcept C164705383 @default.
• W2897843357 hasConcept C168563851 @default.
• W2897843357 hasConcept C203092338 @default.
• W2897843357 hasConcept C2777849778 @default.
• W2897843357 hasConcept C2780400711 @default.
• W2897843357 hasConcept C2780645631 @default.
• W2897843357 hasConcept C2780890252 @default.
• W2897843357 hasConcept C27924281 @default.
• W2897843357 hasConcept C35294091 @default.
• W2897843357 hasConcept C42219234 @default.
• W2897843357 hasConcept C500558357 @default.
• W2897843357 hasConcept C71924100 @default.
• W2897843357 hasConcept C78519656 @default.
• W2897843357 hasConceptScore W2897843357C126322002 @default.
• W2897843357 hasConceptScore W2897843357C127413603 @default.
• W2897843357 hasConceptScore W2897843357C156957248 @default.
• W2897843357 hasConceptScore W2897843357C164705383 @default.
• W2897843357 hasConceptScore W2897843357C168563851 @default.

• next