FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897873206> ?p ?o ?g. }

• W2897873206 endingPage "59" @default.
• W2897873206 startingPage "37" @default.
• W2897873206 abstract "Aspergillus nidulans has long-been used as a model organism to gain insights into the genetic basis of asexual and sexual developmental processes both in other members of the genus Aspergillus, and filamentous fungi in general. Paradigms have been established concerning the regulatory mechanisms of conidial development. However, recent studies have shown considerable genome divergence in the fungal kingdom, questioning the general applicability of findings from Aspergillus, and certain longstanding evolutionary theories have been questioned. The phylogenetic distribution of key regulatory elements of asexual reproduction in A. nidulans was investigated in a broad taxonomic range of fungi. This revealed that some proteins were well conserved in the Pezizomycotina (e.g. AbaA, FlbA, FluG, NsdD, MedA, and some velvet proteins), suggesting similar developmental roles. However, other elements (e.g. BrlA) had a more restricted distribution solely in the Eurotiomycetes, and it appears that the genetic control of sporulation seems to be more complex in the aspergilli than in some other taxonomic groups of the Pezizomycotina. The evolution of the velvet protein family is discussed based on the history of expansion and contraction events in the early divergent fungi. Heterologous expression of the A. nidulans abaA gene in Monascus ruber failed to induce development of complete conidiophores as seen in the aspergilli, but did result in increased conidial production. The absence of many components of the asexual developmental pathway from members of the Saccharomycotina supports the hypothesis that differences in the complexity of their spore formation is due in part to the increased diversity of the sporulation machinery evident in the Pezizomycotina. Investigations were also made into the evolution of sex and sexuality in the aspergilli. MAT loci were identified from the heterothallic Aspergillus (Emericella) heterothallicus and Aspergillus (Neosartorya) fennelliae and the homothallic Aspergillus pseudoglaucus (=Eurotium repens). A consistent architecture of the MAT locus was seen in these and other heterothallic aspergilli whereas much variation was seen in the arrangement of MAT loci in homothallic aspergilli. This suggested that it is most likely that the common ancestor of the aspergilli exhibited a heterothallic breeding system. Finally, the supposed prevalence of asexuality in the aspergilli was examined. Investigations were made using A. clavatus as a representative 'asexual' species. It was possible to induce a sexual cycle in A. clavatus given the correct MAT1-1 and MAT1-2 partners and environmental conditions, with recombination confirmed utilising molecular markers. This indicated that sexual reproduction might be possible in many supposedly asexual aspergilli and beyond, providing general insights into the nature of asexuality in fungi." @default.
• W2897873206 created "2018-10-26" @default.
• W2897873206 creator A5023664422 @default.
• W2897873206 creator A5026715251 @default.
• W2897873206 creator A5028728537 @default.
• W2897873206 creator A5044900631 @default.
• W2897873206 creator A5048773499 @default.
• W2897873206 creator A5066867414 @default.
• W2897873206 creator A5072378272 @default.
• W2897873206 creator A5076040181 @default.
• W2897873206 creator A5082856054 @default.
• W2897873206 creator A5083103168 @default.
• W2897873206 creator A5085715303 @default.
• W2897873206 date "2018-09-01" @default.
• W2897873206 modified "2023-10-14" @default.
• W2897873206 title "Evolution of asexual and sexual reproduction in the aspergilli" @default.
• W2897873206 cites W1465122682 @default.
• W2897873206 cites W1534917150 @default.
• W2897873206 cites W1562825381 @default.
• W2897873206 cites W1590049795 @default.
• W2897873206 cites W1591529270 @default.
• W2897873206 cites W1593502693 @default.
• W2897873206 cites W17439892 @default.
• W2897873206 cites W1833422288 @default.
• W2897873206 cites W1837513873 @default.
• W2897873206 cites W1876617638 @default.
• W2897873206 cites W1878508135 @default.
• W2897873206 cites W1889362454 @default.
• W2897873206 cites W1897053563 @default.
• W2897873206 cites W1900937478 @default.
• W2897873206 cites W1904167893 @default.
• W2897873206 cites W1913660929 @default.
• W2897873206 cites W1916670272 @default.
• W2897873206 cites W1962124554 @default.
• W2897873206 cites W1964029522 @default.
• W2897873206 cites W1967651999 @default.
• W2897873206 cites W1972315779 @default.
• W2897873206 cites W1974653674 @default.
• W2897873206 cites W1974878413 @default.
• W2897873206 cites W1974901081 @default.
• W2897873206 cites W1978962117 @default.
• W2897873206 cites W1982882180 @default.
• W2897873206 cites W1983779916 @default.
• W2897873206 cites W1985051937 @default.
• W2897873206 cites W1987916789 @default.
• W2897873206 cites W1989725886 @default.
• W2897873206 cites W1990876235 @default.
• W2897873206 cites W1997437177 @default.
• W2897873206 cites W1999795946 @default.
• W2897873206 cites W2000400158 @default.
• W2897873206 cites W2000649815 @default.
• W2897873206 cites W2001057820 @default.
• W2897873206 cites W2001634520 @default.
• W2897873206 cites W2003442364 @default.
• W2897873206 cites W2004589024 @default.
• W2897873206 cites W2006552859 @default.
• W2897873206 cites W2006716729 @default.
• W2897873206 cites W2010091762 @default.
• W2897873206 cites W2011361437 @default.
• W2897873206 cites W2014256804 @default.
• W2897873206 cites W2019612872 @default.
• W2897873206 cites W2020682691 @default.
• W2897873206 cites W2022680565 @default.
• W2897873206 cites W2024516443 @default.
• W2897873206 cites W2028640502 @default.
• W2897873206 cites W2029013042 @default.
• W2897873206 cites W2035282264 @default.
• W2897873206 cites W2037082423 @default.
• W2897873206 cites W2038547721 @default.
• W2897873206 cites W2038624968 @default.
• W2897873206 cites W2039777006 @default.
• W2897873206 cites W2041611856 @default.
• W2897873206 cites W2043095804 @default.
• W2897873206 cites W2045444560 @default.
• W2897873206 cites W2046075462 @default.
• W2897873206 cites W2047195096 @default.
• W2897873206 cites W2047320462 @default.
• W2897873206 cites W2050074420 @default.
• W2897873206 cites W2052375196 @default.
• W2897873206 cites W2052639804 @default.
• W2897873206 cites W2057022975 @default.
• W2897873206 cites W2058099105 @default.
• W2897873206 cites W2058216045 @default.
• W2897873206 cites W2060809284 @default.
• W2897873206 cites W2062363739 @default.
• W2897873206 cites W2067089000 @default.
• W2897873206 cites W2067886846 @default.
• W2897873206 cites W2068325863 @default.
• W2897873206 cites W2070641649 @default.
• W2897873206 cites W2070916151 @default.
• W2897873206 cites W2073404280 @default.
• W2897873206 cites W2074722678 @default.
• W2897873206 cites W2076067000 @default.
• W2897873206 cites W2077180966 @default.
• W2897873206 cites W2083162542 @default.
• W2897873206 cites W2084965683 @default.
• W2897873206 cites W2086239441 @default.
• W2897873206 cites W2091385671 @default.

• next