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- W2897898771 abstract "The aim of the present study was to determine whether the long limb bones femur and humerus measured in the exact plane with 3D ultrasound are reliable parameters to detect Trisomy 21 fetuses in the second trimester. Femur and humerus lengths of 72 fetuses with confirmed Trisomy 21 were compared with normal growth charts. All scans were performed using 3D ultrasound with E8/E10 GE equipment (Zipf, Austria) with a 5-8 MHz 3D abdominal transducer. Gestational age was between 14+0 and 27+0 weeks of gestation. 25/72 fetuses with Trisomy 21 (34.7%) showed femur lengths below the 5th percentile, while the values of the remaining 47 fetuses (65.3%) were within the normal range. 18/72 fetuses with Trisomy 21 (25.0%) showed humerus lengths below the 5th percentile, while the values of the remaining 47 fetuses (65.3%) were within or above the normal range. When using 3D ultrasound for the measurement of the long limb bones femur and humerus in the exact anatomical plane, only 1/3 of the Trisomy 21 fetuses were characterised by a reduced femur length and only 1/4 of the Trisomy 21 fetuses had a reduced humerus length in the second trimester. Therefore both parameters are not very reliable parameters for the detection of Trisomy 21. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W2897898771 created "2018-10-26" @default.
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- W2897898771 date "2018-10-01" @default.
- W2897898771 modified "2023-10-18" @default.
- W2897898771 title "EP11.09: Are femur and humerus lengths measured exactly by 3D ultrasound reliable parameters for the detection of Trisomy 21 in the second trimester?" @default.
- W2897898771 doi "https://doi.org/10.1002/uog.19969" @default.
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