FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897900908> ?p ?o ?g. }

• W2897900908 endingPage "e1007778" @default.
• W2897900908 startingPage "e1007778" @default.
• W2897900908 abstract "Extrachromosomal genetic elements such as bacterial endosymbionts and plasmids generally exhibit AT-contents that are increased relative to their hosts’ DNA. The AT-bias of endosymbiotic genomes is commonly explained by neutral evolutionary processes such as a mutational bias towards increased A+T. Here we show experimentally that an increased AT-content of host-dependent elements can be selectively favoured. Manipulating the nucleotide composition of bacterial cells by introducing A+T-rich or G+C-rich plasmids, we demonstrate that cells containing GC-rich plasmids are less fit than cells containing AT-rich plasmids. Moreover, the cost of GC-rich elements could be compensated by providing precursors of G+C, but not of A+T, thus linking the observed fitness effects to the cytoplasmic availability of nucleotides. Accordingly, introducing AT-rich and GC-rich plasmids into other bacterial species with different genomic GC-contents revealed that the costs of G+C-rich plasmids decreased with an increasing GC-content of their host’s genomic DNA. Taken together, our work identifies selection as a strong evolutionary force that drives the genomes of intracellular genetic elements toward higher A+T contents." @default.
• W2897900908 created "2018-10-26" @default.
• W2897900908 creator A5003139722 @default.
• W2897900908 creator A5008517808 @default.
• W2897900908 creator A5056441789 @default.
• W2897900908 creator A5059004438 @default.
• W2897900908 date "2019-04-29" @default.
• W2897900908 modified "2023-09-25" @default.
• W2897900908 title "Selective advantages favour high genomic AT-contents in intracellular elements" @default.
• W2897900908 cites W104710838 @default.
• W2897900908 cites W1485691750 @default.
• W2897900908 cites W1499500424 @default.
• W2897900908 cites W1579467601 @default.
• W2897900908 cites W1583214634 @default.
• W2897900908 cites W1840916353 @default.
• W2897900908 cites W1936630560 @default.
• W2897900908 cites W1963984053 @default.
• W2897900908 cites W1966050775 @default.
• W2897900908 cites W1967600116 @default.
• W2897900908 cites W1968179480 @default.
• W2897900908 cites W1968894097 @default.
• W2897900908 cites W1989342781 @default.
• W2897900908 cites W2009187135 @default.
• W2897900908 cites W2012270467 @default.
• W2897900908 cites W2017868437 @default.
• W2897900908 cites W2026437584 @default.
• W2897900908 cites W2026916622 @default.
• W2897900908 cites W2043592686 @default.
• W2897900908 cites W2045074917 @default.
• W2897900908 cites W2049066128 @default.
• W2897900908 cites W2052903982 @default.
• W2897900908 cites W2056892325 @default.
• W2897900908 cites W2074656054 @default.
• W2897900908 cites W2076219800 @default.
• W2897900908 cites W2082883430 @default.
• W2897900908 cites W2088415559 @default.
• W2897900908 cites W2089430942 @default.
• W2897900908 cites W2096990469 @default.
• W2897900908 cites W2104948370 @default.
• W2897900908 cites W2105871221 @default.
• W2897900908 cites W2111075099 @default.
• W2897900908 cites W2111967267 @default.
• W2897900908 cites W2113824405 @default.
• W2897900908 cites W2115622704 @default.
• W2897900908 cites W2116137883 @default.
• W2897900908 cites W2124679757 @default.
• W2897900908 cites W2128880918 @default.
• W2897900908 cites W2132417094 @default.
• W2897900908 cites W2143079975 @default.
• W2897900908 cites W2143726250 @default.
• W2897900908 cites W2146495422 @default.
• W2897900908 cites W2147838321 @default.
• W2897900908 cites W2160087043 @default.
• W2897900908 cites W2160174395 @default.
• W2897900908 cites W2160743522 @default.
• W2897900908 cites W2164685855 @default.
• W2897900908 cites W2165206297 @default.
• W2897900908 cites W2166744717 @default.
• W2897900908 cites W2339057086 @default.
• W2897900908 cites W2793666472 @default.
• W2897900908 cites W2797891857 @default.
• W2897900908 cites W4210990206 @default.
• W2897900908 doi "https://doi.org/10.1371/journal.pgen.1007778" @default.
• W2897900908 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6519830" @default.
• W2897900908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31034469" @default.
• W2897900908 hasPublicationYear "2019" @default.
• W2897900908 type Work @default.
• W2897900908 sameAs 2897900908 @default.
• W2897900908 citedByCount "38" @default.
• W2897900908 countsByYear W28979009082019 @default.
• W2897900908 countsByYear W28979009082020 @default.
• W2897900908 countsByYear W28979009082021 @default.
• W2897900908 countsByYear W28979009082022 @default.
• W2897900908 countsByYear W28979009082023 @default.
• W2897900908 crossrefType "journal-article" @default.
• W2897900908 hasAuthorship W2897900908A5003139722 @default.
• W2897900908 hasAuthorship W2897900908A5008517808 @default.
• W2897900908 hasAuthorship W2897900908A5056441789 @default.
• W2897900908 hasAuthorship W2897900908A5059004438 @default.
• W2897900908 hasBestOaLocation W28979009081 @default.
• W2897900908 hasConcept C104317684 @default.
• W2897900908 hasConcept C141231307 @default.
• W2897900908 hasConcept C17757408 @default.
• W2897900908 hasConcept C22744801 @default.
• W2897900908 hasConcept C3742359 @default.
• W2897900908 hasConcept C42251679 @default.
• W2897900908 hasConcept C512185932 @default.
• W2897900908 hasConcept C54355233 @default.
• W2897900908 hasConcept C552990157 @default.
• W2897900908 hasConcept C7386963 @default.
• W2897900908 hasConcept C86803240 @default.
• W2897900908 hasConcept C89684784 @default.
• W2897900908 hasConceptScore W2897900908C104317684 @default.
• W2897900908 hasConceptScore W2897900908C141231307 @default.
• W2897900908 hasConceptScore W2897900908C17757408 @default.
• W2897900908 hasConceptScore W2897900908C22744801 @default.
• W2897900908 hasConceptScore W2897900908C3742359 @default.
• W2897900908 hasConceptScore W2897900908C42251679 @default.

• next