FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897914377> ?p ?o ?g. }

• W2897914377 abstract "Background: Progressively worsening severity of ICA stenosis has been used as an indication for carotid revascularization in asymptomatic patients. However, limited data exists whether progression in severity is actually associated with ipsilateral cerebral ischemic symptoms. Methods: We analyzed data from the Cardiovascular Health Study participants aged ≥65 years who underwent serial carotid Doppler ultrasound (at baseline and 5 year follow up). The severity was classified into four grades by a central reader: 0-24%, 25-49%, 50-69%, 70-99%, and complete occlusion. We selected patients who were asymptomatic at baseline and not undergone carotid endertectomy. Progressively worsening severity of internal carotid artery stenosis was defined if the severity of ICA with highest velocity at baseline evaluation had increased by one grade or greater at 5 year follow up. Incident cardiovascular events were identified during annual follow-up examinations and at 6-month telephone contact and adjudicated by a central committee. Hazards ratio for cardiovascular events during follow up were estimated using Cox proportional Hazards analysis. Results: Progressively worsening severity of internal carotid artery stenosis was observed in 1551 (26.3%) of 5,888 study participants (57.2% women; mean baseline age, 72.7 ± 5.1 years). The rate of ipsilateral ischemic stroke was similar among patients with and without progressively worsening severity of internal carotid artery stenosis over a mean follow up period (mean ±SD) of 7.3 ± 1 years. The risk of any ischemic stroke was (HR 1.3, 95% confidence interval [CI] 1.0-1.6) but not ipsilateral ischemic stroke (HR 1.4, 95% CI 0.6 - 3.1) was statistically higher among patients with progressively worsening severity of internal carotid artery stenosis after adjusting for age, race, serum cholesterol, diabetes mellitus, blood pressure and cigarette smoking. The risk of MI (HR 1.3, 95% CI 1.1-1.7) was significantly higher among patients with progressively worsening severity of internal carotid artery stenosis. Conclusions: Patients with progressively worsening severity of internal carotid artery stenosis appear to be at higher risk of cardiovascular events but not ipsilateral cerebral ischemic symptoms." @default.
• W2897914377 created "2018-10-26" @default.
• W2897914377 creator A5013047796 @default.
• W2897914377 creator A5020049468 @default.
• W2897914377 creator A5065189454 @default.
• W2897914377 date "2018-01-22" @default.
• W2897914377 modified "2023-09-24" @default.
• W2897914377 title "Abstract 85: Is Progressively Worsening Severity of Internal Carotid Artery Stenosis by Carotid Doppler Ultrasound in Asymptomatic Patients a Risk Factor for Ischemic Stroke?" @default.
• W2897914377 doi "https://doi.org/10.1161/str.49.suppl_1.85" @default.
• W2897914377 hasPublicationYear "2018" @default.
• W2897914377 type Work @default.
• W2897914377 sameAs 2897914377 @default.
• W2897914377 citedByCount "0" @default.
• W2897914377 crossrefType "journal-article" @default.
• W2897914377 hasAuthorship W2897914377A5013047796 @default.
• W2897914377 hasAuthorship W2897914377A5020049468 @default.
• W2897914377 hasAuthorship W2897914377A5065189454 @default.
• W2897914377 hasConcept C126322002 @default.
• W2897914377 hasConcept C126838900 @default.
• W2897914377 hasConcept C127413603 @default.
• W2897914377 hasConcept C143753070 @default.
• W2897914377 hasConcept C164705383 @default.
• W2897914377 hasConcept C191616109 @default.
• W2897914377 hasConcept C2777910003 @default.
• W2897914377 hasConcept C2778333808 @default.
• W2897914377 hasConcept C2780007028 @default.
• W2897914377 hasConcept C2780645631 @default.
• W2897914377 hasConcept C2987047532 @default.
• W2897914377 hasConcept C2988078883 @default.
• W2897914377 hasConcept C3020199598 @default.
• W2897914377 hasConcept C50440223 @default.
• W2897914377 hasConcept C541997718 @default.
• W2897914377 hasConcept C71924100 @default.
• W2897914377 hasConcept C78519656 @default.
• W2897914377 hasConceptScore W2897914377C126322002 @default.
• W2897914377 hasConceptScore W2897914377C126838900 @default.
• W2897914377 hasConceptScore W2897914377C127413603 @default.
• W2897914377 hasConceptScore W2897914377C143753070 @default.
• W2897914377 hasConceptScore W2897914377C164705383 @default.
• W2897914377 hasConceptScore W2897914377C191616109 @default.
• W2897914377 hasConceptScore W2897914377C2777910003 @default.
• W2897914377 hasConceptScore W2897914377C2778333808 @default.
• W2897914377 hasConceptScore W2897914377C2780007028 @default.
• W2897914377 hasConceptScore W2897914377C2780645631 @default.
• W2897914377 hasConceptScore W2897914377C2987047532 @default.
• W2897914377 hasConceptScore W2897914377C2988078883 @default.
• W2897914377 hasConceptScore W2897914377C3020199598 @default.
• W2897914377 hasConceptScore W2897914377C50440223 @default.
• W2897914377 hasConceptScore W2897914377C541997718 @default.
• W2897914377 hasConceptScore W2897914377C71924100 @default.
• W2897914377 hasConceptScore W2897914377C78519656 @default.
• W2897914377 hasIssue "Suppl_1" @default.
• W2897914377 hasLocation W28979143771 @default.
• W2897914377 hasOpenAccess W2897914377 @default.
• W2897914377 hasPrimaryLocation W28979143771 @default.
• W2897914377 hasRelatedWork W1487798714 @default.
• W2897914377 hasRelatedWork W1618436976 @default.
• W2897914377 hasRelatedWork W175027 @default.
• W2897914377 hasRelatedWork W1766497733 @default.
• W2897914377 hasRelatedWork W1916622243 @default.
• W2897914377 hasRelatedWork W1990286995 @default.
• W2897914377 hasRelatedWork W2064568187 @default.
• W2897914377 hasRelatedWork W2078883959 @default.
• W2897914377 hasRelatedWork W2291843923 @default.
• W2897914377 hasRelatedWork W2340467326 @default.
• W2897914377 hasRelatedWork W2380923801 @default.
• W2897914377 hasRelatedWork W2424199619 @default.
• W2897914377 hasRelatedWork W24450880 @default.
• W2897914377 hasRelatedWork W2476552881 @default.
• W2897914377 hasRelatedWork W2885392472 @default.
• W2897914377 hasRelatedWork W2885950833 @default.
• W2897914377 hasRelatedWork W2902407235 @default.
• W2897914377 hasRelatedWork W2945880237 @default.
• W2897914377 hasRelatedWork W3034415919 @default.
• W2897914377 hasRelatedWork W3134200297 @default.
• W2897914377 hasVolume "49" @default.
• W2897914377 isParatext "false" @default.
• W2897914377 isRetracted "false" @default.
• W2897914377 magId "2897914377" @default.
• W2897914377 workType "article" @default.