Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897928411> ?p ?o ?g. }
- W2897928411 endingPage "1213" @default.
- W2897928411 startingPage "1205" @default.
- W2897928411 abstract "To investigate whether prophylactic amiodarone infusion prevents ventricular fibrillation after aortic cross-clamp release and attenuates cytokine production in patients with left ventricular hypertrophy undergoing cardiac surgery.Prospective, randomized controlled trial.A public hospital.The study comprised 68 patients undergoing aortic valve replacement for severe aortic stenosis.Patients were randomly assigned to receive a 150mg bolus then 30mg/h continuous infusion of amiodarone (amiodarone group) or a 1 mg/kg bolus then 1 mg/kg/h continuous infusion of lidocaine (lidocaine group). The primary outcome was the ventricular fibrillation incidence rate after aortic cross-clamp release. Secondary outcomes included perioperative serum interleukin-6 and tumor necrosis factor-alpha levels.The ventricular fibrillation incidence rate was significantly lower in the amiodarone than in the lidocaine group (20.6% v 50%, relative risk 0.41; 95% confidence interval [CI] 0.20-0.86; p = 0.021). Interleukin-6 levels 1hour after aortic cross-clamp release and at intensive care unit admission were significantly lower in the amiodarone than in the lidocaine group (geometric mean [95% CI] 117.4pg/mL [87.1-158.4] v 339.5pg/mL [210.6-547.2]; p < 0.01 and 211.1pg/mL [162.8-73.6] v 434.1pg/mL [293.7-641.5]; p < 0.01, respectively). Tumor necrosis factor-alpha levels 1hour after aortic cross-clamp release were significantly lower in the amiodarone than in the lidocaine group (geometric mean [95% CI] 1.624pg/mL [1.359-1.940] v 2.283pg/mL [1.910-2.731]; p = 0.02).Amiodarone prevented reperfusion ventricular fibrillation in patients with left ventricular hypertrophy undergoing aortic valve replacement to a greater extent than did lidocaine. Furthermore, amiodarone inhibited postoperative interleukin-6 and tumor necrosis factor-alpha production." @default.
- W2897928411 created "2018-10-26" @default.
- W2897928411 creator A5004980476 @default.
- W2897928411 creator A5011013472 @default.
- W2897928411 creator A5060552958 @default.
- W2897928411 creator A5084766578 @default.
- W2897928411 date "2019-05-01" @default.
- W2897928411 modified "2023-09-27" @default.
- W2897928411 title "Prophylactic Effect of Amiodarone Infusion on Reperfusion Ventricular Fibrillation After Release of Aortic Cross-Clamp in Patients with Left Ventricular Hypertrophy Undergoing Aortic Valve Replacement: ARandomized Controlled Trial" @default.
- W2897928411 cites W1541550846 @default.
- W2897928411 cites W1909851795 @default.
- W2897928411 cites W1964404852 @default.
- W2897928411 cites W1985061340 @default.
- W2897928411 cites W1986422359 @default.
- W2897928411 cites W1987083085 @default.
- W2897928411 cites W1987395472 @default.
- W2897928411 cites W1987523161 @default.
- W2897928411 cites W1992603152 @default.
- W2897928411 cites W1993726528 @default.
- W2897928411 cites W1995770457 @default.
- W2897928411 cites W2009370819 @default.
- W2897928411 cites W2010523286 @default.
- W2897928411 cites W2019336469 @default.
- W2897928411 cites W2020145633 @default.
- W2897928411 cites W2023002615 @default.
- W2897928411 cites W2036316113 @default.
- W2897928411 cites W2038504749 @default.
- W2897928411 cites W2039597310 @default.
- W2897928411 cites W2068460244 @default.
- W2897928411 cites W2071018715 @default.
- W2897928411 cites W2075639684 @default.
- W2897928411 cites W2081051853 @default.
- W2897928411 cites W2084814020 @default.
- W2897928411 cites W2113655937 @default.
- W2897928411 cites W2121960517 @default.
- W2897928411 cites W2124624517 @default.
- W2897928411 cites W2166169466 @default.
- W2897928411 cites W294297612 @default.
- W2897928411 doi "https://doi.org/10.1053/j.jvca.2018.10.005" @default.
- W2897928411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30416026" @default.
- W2897928411 hasPublicationYear "2019" @default.
- W2897928411 type Work @default.
- W2897928411 sameAs 2897928411 @default.
- W2897928411 citedByCount "4" @default.
- W2897928411 countsByYear W28979284112020 @default.
- W2897928411 countsByYear W28979284112022 @default.
- W2897928411 countsByYear W28979284112023 @default.
- W2897928411 crossrefType "journal-article" @default.
- W2897928411 hasAuthorship W2897928411A5004980476 @default.
- W2897928411 hasAuthorship W2897928411A5011013472 @default.
- W2897928411 hasAuthorship W2897928411A5060552958 @default.
- W2897928411 hasAuthorship W2897928411A5084766578 @default.
- W2897928411 hasConcept C126322002 @default.
- W2897928411 hasConcept C164705383 @default.
- W2897928411 hasConcept C2776483784 @default.
- W2897928411 hasConcept C2776570981 @default.
- W2897928411 hasConcept C2778094803 @default.
- W2897928411 hasConcept C2778131192 @default.
- W2897928411 hasConcept C2778881276 @default.
- W2897928411 hasConcept C2779161974 @default.
- W2897928411 hasConcept C2780007028 @default.
- W2897928411 hasConcept C2780074459 @default.
- W2897928411 hasConcept C2780149897 @default.
- W2897928411 hasConcept C2781005686 @default.
- W2897928411 hasConcept C42219234 @default.
- W2897928411 hasConcept C71924100 @default.
- W2897928411 hasConceptScore W2897928411C126322002 @default.
- W2897928411 hasConceptScore W2897928411C164705383 @default.
- W2897928411 hasConceptScore W2897928411C2776483784 @default.
- W2897928411 hasConceptScore W2897928411C2776570981 @default.
- W2897928411 hasConceptScore W2897928411C2778094803 @default.
- W2897928411 hasConceptScore W2897928411C2778131192 @default.
- W2897928411 hasConceptScore W2897928411C2778881276 @default.
- W2897928411 hasConceptScore W2897928411C2779161974 @default.
- W2897928411 hasConceptScore W2897928411C2780007028 @default.
- W2897928411 hasConceptScore W2897928411C2780074459 @default.
- W2897928411 hasConceptScore W2897928411C2780149897 @default.
- W2897928411 hasConceptScore W2897928411C2781005686 @default.
- W2897928411 hasConceptScore W2897928411C42219234 @default.
- W2897928411 hasConceptScore W2897928411C71924100 @default.
- W2897928411 hasIssue "5" @default.
- W2897928411 hasLocation W28979284111 @default.
- W2897928411 hasLocation W28979284112 @default.
- W2897928411 hasOpenAccess W2897928411 @default.
- W2897928411 hasPrimaryLocation W28979284111 @default.
- W2897928411 hasRelatedWork W147835578 @default.
- W2897928411 hasRelatedWork W1985061340 @default.
- W2897928411 hasRelatedWork W2010626010 @default.
- W2897928411 hasRelatedWork W2017360789 @default.
- W2897928411 hasRelatedWork W2021716176 @default.
- W2897928411 hasRelatedWork W2068460244 @default.
- W2897928411 hasRelatedWork W2425285670 @default.
- W2897928411 hasRelatedWork W2897928411 @default.
- W2897928411 hasRelatedWork W4308001865 @default.
- W2897928411 hasRelatedWork W4313208434 @default.
- W2897928411 hasVolume "33" @default.
- W2897928411 isParatext "false" @default.
- W2897928411 isRetracted "false" @default.