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- W2897930546 abstract "Abstract With technical breakthroughs in the throughput and read-length of next-generation sequencing platforms, antibody repertoire sequencing is becoming an increasingly important tool for detailed characterization of the immune response. There is a need for open, scalable software for the genetic analysis of repertoire-scale antibody sequence data. To address this gap, we have developed the ab[x] package of software tools. There are three core components of the ab[x] toolkit, all of which are freely available: abcloud ( github.com/briney/abcloud ) for deployment and management of computational resources on Amazon’s Elastic Compute Cloud; abstar ( github.com/briney/abstar ) for pre-processing, germline gene assignment and primary annotation of antibody sequence data; and abutils ( github.com/briney/abutils ), which provides utilities for interactive downstream analysis of antibody repertoire data." @default.
- W2897930546 created "2018-10-26" @default.
- W2897930546 creator A5058546353 @default.
- W2897930546 creator A5067720514 @default.
- W2897930546 date "2018-10-19" @default.
- W2897930546 modified "2023-10-01" @default.
- W2897930546 title "Massively scalable genetic analysis of antibody repertoires" @default.
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- W2897930546 doi "https://doi.org/10.1101/447813" @default.
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