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- W2897937276 abstract "The blood-brain barrier (BBB) is a complex and highly selective barrier, made of endothelial cells, pericytes, basement membrane, astrocytes, and tight junctions. BBB protects the central nervous system from aberrant exposure to toxins and even drugs. It is important to determine the extent of drugs that can be delivered to CNS through BBB and for which different in vitro and in vivo models have been utilized. The in vitro models utilized for assessment of drug delivery through BBB are based on synthetic materials or cell cultures originated from animal brains or human stem cells. Also, different animals have been utilized to create in vivo models to assess drug delivery through BBB; commonest are rodents. Various researchers have utilized many analytical techniques in these in vitro and in vivo models, to assess the possible delivery of different drugs that may be delivered through BBB. This chapter covers such in vitro models, in vivo models, and analytical techniques, which can be used in tandem with each other to assess the delivery of variety of agents through BBB." @default.
- W2897937276 created "2018-10-26" @default.
- W2897937276 creator A5003730073 @default.
- W2897937276 creator A5027888114 @default.
- W2897937276 creator A5068118838 @default.
- W2897937276 date "2019-01-01" @default.
- W2897937276 modified "2023-10-01" @default.
- W2897937276 title "In vitro and in vivo models of BBB to evaluate brain targeting drug delivery" @default.
- W2897937276 cites W1520987766 @default.
- W2897937276 cites W1548840271 @default.
- W2897937276 cites W1575659578 @default.
- W2897937276 cites W1581321319 @default.
- W2897937276 cites W1589765527 @default.
- W2897937276 cites W1606934029 @default.
- W2897937276 cites W1619037645 @default.
- W2897937276 cites W1734296561 @default.
- W2897937276 cites W174314275 @default.
- W2897937276 cites W1796054280 @default.
- W2897937276 cites W1852676216 @default.
- W2897937276 cites W187680792 @default.
- W2897937276 cites W1902114397 @default.
- W2897937276 cites W1902782356 @default.
- W2897937276 cites W1964200363 @default.
- W2897937276 cites W1964956174 @default.
- W2897937276 cites W1965522214 @default.
- W2897937276 cites W1965838612 @default.
- W2897937276 cites W1968150858 @default.
- W2897937276 cites W1968636798 @default.
- W2897937276 cites W1969818467 @default.
- W2897937276 cites W1969963281 @default.
- W2897937276 cites W1970730429 @default.
- W2897937276 cites W1971467209 @default.
- W2897937276 cites W1972326404 @default.
- W2897937276 cites W1972847156 @default.
- W2897937276 cites W1973485004 @default.
- W2897937276 cites W1973544766 @default.
- W2897937276 cites W1974129665 @default.
- W2897937276 cites W1974624515 @default.
- W2897937276 cites W1976386474 @default.
- W2897937276 cites W1976536825 @default.
- W2897937276 cites W1979386915 @default.
- W2897937276 cites W1979770296 @default.
- W2897937276 cites W1980370917 @default.
- W2897937276 cites W1980773166 @default.
- W2897937276 cites W1980783002 @default.
- W2897937276 cites W1981425827 @default.
- W2897937276 cites W1982252520 @default.
- W2897937276 cites W1982883013 @default.
- W2897937276 cites W1983116993 @default.
- W2897937276 cites W1983512668 @default.
- W2897937276 cites W1983556296 @default.
- W2897937276 cites W1983893444 @default.
- W2897937276 cites W1984360588 @default.
- W2897937276 cites W1984399394 @default.
- W2897937276 cites W1985265644 @default.
- W2897937276 cites W1985944040 @default.
- W2897937276 cites W1986499063 @default.
- W2897937276 cites W1986873161 @default.
- W2897937276 cites W1988474837 @default.
- W2897937276 cites W1988907150 @default.
- W2897937276 cites W1990250882 @default.
- W2897937276 cites W1990578850 @default.
- W2897937276 cites W1991064261 @default.
- W2897937276 cites W1991155077 @default.
- W2897937276 cites W1991680358 @default.
- W2897937276 cites W1991743260 @default.
- W2897937276 cites W1991906491 @default.
- W2897937276 cites W1993077697 @default.
- W2897937276 cites W1993192173 @default.
- W2897937276 cites W1993640941 @default.
- W2897937276 cites W1994504209 @default.
- W2897937276 cites W1994504773 @default.
- W2897937276 cites W1994812037 @default.
- W2897937276 cites W1994902496 @default.
- W2897937276 cites W1994991276 @default.
- W2897937276 cites W1995063875 @default.
- W2897937276 cites W1995840887 @default.
- W2897937276 cites W1996719014 @default.
- W2897937276 cites W1998531393 @default.
- W2897937276 cites W2000208781 @default.
- W2897937276 cites W2001438714 @default.
- W2897937276 cites W2001552996 @default.
- W2897937276 cites W2001726213 @default.
- W2897937276 cites W2002878845 @default.
- W2897937276 cites W2003974648 @default.
- W2897937276 cites W2004935958 @default.
- W2897937276 cites W2004956687 @default.
- W2897937276 cites W2005447528 @default.
- W2897937276 cites W2006572450 @default.
- W2897937276 cites W2006840751 @default.
- W2897937276 cites W2008496982 @default.
- W2897937276 cites W2008737907 @default.
- W2897937276 cites W2009081910 @default.
- W2897937276 cites W2009244092 @default.
- W2897937276 cites W2010444608 @default.
- W2897937276 cites W2011578064 @default.
- W2897937276 cites W2013495726 @default.
- W2897937276 cites W2013865714 @default.