FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897946787> ?p ?o ?g. }

• W2897946787 abstract "Introduction: Clinical vasospasm and delayed cerebral ischemia (DCI) are devastating complications of aneurysmal subarachnoid hemorrhage (aSAH). Several theories have been postulated as potential etiologies of clinical vasospasm and DCI, involving platelet activation. However, the effects of dual anti-platelet therapy (DAPT: aspirin and clopidogrel) on clinical vasospasm and DCI have not been previously investigated. The objective of this study was to evaluate the effects of DAPT on clinical vasospasm and DCI in aSAH patients. Methods: Analysis of patients treated for aSAH during the period from July 2009 to April 2014 was performed in a single-institution retrospective study. Patients were divided into two groups: patients who underwent stent-assisted coiling or placement of flow diverters requiring DAPT (DAPT group) and patients who underwent coiling only without DAPT (control group). The frequency of symptomatic clinical vasospasm and DCI and of hemorrhagic complications was compared between the two groups, utilizing univariate and multivariate logistic regression. Results: Of 312 aSAH patients considered for this study, 161 patients met the inclusion and exclusion criteria and were included in the analysis (85 patients in the DAPT group and 76 patients in the control group). The risk of clinical vasospasm (OR: 0.244; CI 95% [0.097 - 0.615]; p = 0.003) and DCI (OR: 0.056; CI 95% [0.01 - 0.318]; p = 0.001) were significantly lower in patients receiving DAPT. Hemorrhagic complications associated with placement of external ventricular drains and ventriculoperitoneal shunts were similar in both groups (4% versus 2%; p = 0.9). Conclusions: The use of DAPT was associated with a lower risk of clinical vasospasm and DCI in patients treated for aSAH without an increased risk of hemorrhagic complications." @default.
• W2897946787 created "2018-10-26" @default.
• W2897946787 creator A5004062581 @default.
• W2897946787 creator A5035072166 @default.
• W2897946787 creator A5043799442 @default.
• W2897946787 date "2018-01-22" @default.
• W2897946787 modified "2023-10-16" @default.
• W2897946787 title "Abstract TP401: Dual Anti-platelet Therapy is Associated With Reduced Risk of Clinical Vasospasm and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage" @default.
• W2897946787 doi "https://doi.org/10.1161/str.49.suppl_1.tp401" @default.
• W2897946787 hasPublicationYear "2018" @default.
• W2897946787 type Work @default.
• W2897946787 sameAs 2897946787 @default.
• W2897946787 citedByCount "0" @default.
• W2897946787 crossrefType "journal-article" @default.
• W2897946787 hasAuthorship W2897946787A5004062581 @default.
• W2897946787 hasAuthorship W2897946787A5035072166 @default.
• W2897946787 hasAuthorship W2897946787A5043799442 @default.
• W2897946787 hasConcept C126322002 @default.
• W2897946787 hasConcept C164705383 @default.
• W2897946787 hasConcept C2776820941 @default.
• W2897946787 hasConcept C2777628954 @default.
• W2897946787 hasConcept C2777736543 @default.
• W2897946787 hasConcept C2777849778 @default.
• W2897946787 hasConcept C2778506911 @default.
• W2897946787 hasConcept C42219234 @default.
• W2897946787 hasConcept C541997718 @default.
• W2897946787 hasConcept C71924100 @default.
• W2897946787 hasConceptScore W2897946787C126322002 @default.
• W2897946787 hasConceptScore W2897946787C164705383 @default.
• W2897946787 hasConceptScore W2897946787C2776820941 @default.
• W2897946787 hasConceptScore W2897946787C2777628954 @default.
• W2897946787 hasConceptScore W2897946787C2777736543 @default.
• W2897946787 hasConceptScore W2897946787C2777849778 @default.
• W2897946787 hasConceptScore W2897946787C2778506911 @default.
• W2897946787 hasConceptScore W2897946787C42219234 @default.
• W2897946787 hasConceptScore W2897946787C541997718 @default.
• W2897946787 hasConceptScore W2897946787C71924100 @default.
• W2897946787 hasIssue "Suppl_1" @default.
• W2897946787 hasLocation W28979467871 @default.
• W2897946787 hasOpenAccess W2897946787 @default.
• W2897946787 hasPrimaryLocation W28979467871 @default.
• W2897946787 hasRelatedWork W2050802868 @default.
• W2897946787 hasRelatedWork W2106938293 @default.
• W2897946787 hasRelatedWork W2405983805 @default.
• W2897946787 hasRelatedWork W2413781940 @default.
• W2897946787 hasRelatedWork W2465613368 @default.
• W2897946787 hasRelatedWork W2760198213 @default.
• W2897946787 hasRelatedWork W2893250723 @default.
• W2897946787 hasRelatedWork W3197324045 @default.
• W2897946787 hasRelatedWork W3208658328 @default.
• W2897946787 hasRelatedWork W3032372237 @default.
• W2897946787 hasVolume "49" @default.
• W2897946787 isParatext "false" @default.
• W2897946787 isRetracted "false" @default.
• W2897946787 magId "2897946787" @default.
• W2897946787 workType "article" @default.