Matches in SemOpenAlex for { <https://semopenalex.org/work/W289795013> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W289795013 abstract "Lipoxins and lipoxenes have been reported to be formed after incubation of 15-hydroperoxyeicosatetraenoic acid and 15-hydroperoxyeicosapentaenoic acid with human leukocytes and porcine leukocytes, respectively. The authors examined the ability of porcine leukocytes to metabolize (/sup 14/C)-AA and (/sup 14/C)-EPA (100 ..mu..M) to lipoxins and lipoxenes. Incubation products were separated by RP-HPLC and identified by U.V. spectrum and GC/MS. Porcine leukocytes metabolized both AA and EPA to form lipoxins and lipoxenes in addition to mono- and di-hydroxyl fatty acids. Quantitative analysis from U.V. absorbance after RP-HPLC revealed that about 0.05% of AA was converted to lipoxins A and B and 0.1% of EPA was converted to lipoxenes A and B. In addition, treatment of leukotriene A/sub 4/ and leukotriene A/sub 5/ with 15-lipoxygenase also gave rise to several isomers of lipoxin and lipoxene. Thus, lipoxins and lipoxenes would have been derived from AA and EPA after dioxygenation by 5-lipoxygenase and 15-lipoxygenase, respectively. When tested for biological activity, lipoxene A (2 ..mu..M), like lipoxin A, induced superoxide anion generation in canine neutrophils but had no effect on lysosomal enzyme release on neutrophil aggregation." @default.
- W289795013 created "2016-06-24" @default.
- W289795013 creator A5023635104 @default.
- W289795013 creator A5032735859 @default.
- W289795013 creator A5033267044 @default.
- W289795013 creator A5037236889 @default.
- W289795013 creator A5084170135 @default.
- W289795013 creator A5088889387 @default.
- W289795013 date "1986-03-05" @default.
- W289795013 modified "2023-09-23" @default.
- W289795013 title "Biotransformation of arachidonic acid (AA) and eicosapentaenoic acid (EPA) into lipoxins and lipoxenes by porcine leukocytes" @default.
- W289795013 hasPublicationYear "1986" @default.
- W289795013 type Work @default.
- W289795013 sameAs 289795013 @default.
- W289795013 citedByCount "1" @default.
- W289795013 crossrefType "journal-article" @default.
- W289795013 hasAuthorship W289795013A5023635104 @default.
- W289795013 hasAuthorship W289795013A5032735859 @default.
- W289795013 hasAuthorship W289795013A5033267044 @default.
- W289795013 hasAuthorship W289795013A5037236889 @default.
- W289795013 hasAuthorship W289795013A5084170135 @default.
- W289795013 hasAuthorship W289795013A5088889387 @default.
- W289795013 hasConcept C170493617 @default.
- W289795013 hasConcept C179998833 @default.
- W289795013 hasConcept C181199279 @default.
- W289795013 hasConcept C185592680 @default.
- W289795013 hasConcept C19038510 @default.
- W289795013 hasConcept C203014093 @default.
- W289795013 hasConcept C25642318 @default.
- W289795013 hasConcept C2776042228 @default.
- W289795013 hasConcept C2776091944 @default.
- W289795013 hasConcept C2776352991 @default.
- W289795013 hasConcept C2776452501 @default.
- W289795013 hasConcept C2778078955 @default.
- W289795013 hasConcept C2779630222 @default.
- W289795013 hasConcept C2780415110 @default.
- W289795013 hasConcept C2780857362 @default.
- W289795013 hasConcept C27881333 @default.
- W289795013 hasConcept C43617362 @default.
- W289795013 hasConcept C543025807 @default.
- W289795013 hasConcept C55493867 @default.
- W289795013 hasConcept C86803240 @default.
- W289795013 hasConcept C90342290 @default.
- W289795013 hasConceptScore W289795013C170493617 @default.
- W289795013 hasConceptScore W289795013C179998833 @default.
- W289795013 hasConceptScore W289795013C181199279 @default.
- W289795013 hasConceptScore W289795013C185592680 @default.
- W289795013 hasConceptScore W289795013C19038510 @default.
- W289795013 hasConceptScore W289795013C203014093 @default.
- W289795013 hasConceptScore W289795013C25642318 @default.
- W289795013 hasConceptScore W289795013C2776042228 @default.
- W289795013 hasConceptScore W289795013C2776091944 @default.
- W289795013 hasConceptScore W289795013C2776352991 @default.
- W289795013 hasConceptScore W289795013C2776452501 @default.
- W289795013 hasConceptScore W289795013C2778078955 @default.
- W289795013 hasConceptScore W289795013C2779630222 @default.
- W289795013 hasConceptScore W289795013C2780415110 @default.
- W289795013 hasConceptScore W289795013C2780857362 @default.
- W289795013 hasConceptScore W289795013C27881333 @default.
- W289795013 hasConceptScore W289795013C43617362 @default.
- W289795013 hasConceptScore W289795013C543025807 @default.
- W289795013 hasConceptScore W289795013C55493867 @default.
- W289795013 hasConceptScore W289795013C86803240 @default.
- W289795013 hasConceptScore W289795013C90342290 @default.
- W289795013 hasLocation W2897950131 @default.
- W289795013 hasOpenAccess W289795013 @default.
- W289795013 hasPrimaryLocation W2897950131 @default.
- W289795013 hasRelatedWork W1517088677 @default.
- W289795013 hasRelatedWork W157649625 @default.
- W289795013 hasRelatedWork W1604010542 @default.
- W289795013 hasRelatedWork W1624875646 @default.
- W289795013 hasRelatedWork W1851222141 @default.
- W289795013 hasRelatedWork W1966303693 @default.
- W289795013 hasRelatedWork W2003393498 @default.
- W289795013 hasRelatedWork W2015187192 @default.
- W289795013 hasRelatedWork W2022546597 @default.
- W289795013 hasRelatedWork W2026807169 @default.
- W289795013 hasRelatedWork W2052007942 @default.
- W289795013 hasRelatedWork W2054893856 @default.
- W289795013 hasRelatedWork W2055038552 @default.
- W289795013 hasRelatedWork W2073129310 @default.
- W289795013 hasRelatedWork W2079332429 @default.
- W289795013 hasRelatedWork W2092409117 @default.
- W289795013 hasRelatedWork W2097685656 @default.
- W289795013 hasRelatedWork W2104508962 @default.
- W289795013 hasRelatedWork W2174264341 @default.
- W289795013 hasRelatedWork W310663826 @default.
- W289795013 isParatext "false" @default.
- W289795013 isRetracted "false" @default.
- W289795013 magId "289795013" @default.
- W289795013 workType "article" @default.