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- W2897958657 startingPage "441014" @default.
- W2897958657 abstract "Understanding visual processing requires a detailed description of computations performed by neurons across stages of the visual system. However, the diverse tunings of neurons beyond the primary visual cortex (V1) have yet to be fully characterized. Using two-photon calcium imaging and a stochastic visual stimulus, we catalogued the response properties of a dense sample of 40,000 neurons in V1 and six secondary visual areas of awake mice. All areas encode unique sets of features with distinct spatiotemporal preferences, motion speed selectivity, and responses to oriented and non-oriented stimuli. Central areas V1 and LM have the most diverse tunings, with distributed spatiotemporal preferences and a moderate bias for non-oriented stimuli. Preferences of V1 and LM neurons differ strikingly showing tuning to low and midrange spatiotemporal frequencies, respectively. Lateral areas PM and LI are highly biased towards high spatial and low temporal frequencies, showing weak selectivity for motion speed. Anterior areas AL, RL and AM are highly biased towards high temporal frequencies and have the largest proportion of motion tuned cells. Accordingly, activity patterns in these areas carry more information about motion speed than any other visual areas. With regards to spatial preferences, LI differs strikingly from PM and anterior areas in that it is heavily biased towards non-oriented stimuli. The data provides a detailed description of the segregation of encoding of spatiotemporal feature in the rodent visual cortex and provides a stark demonstration of the high functional specialization of visual areas." @default.
- W2897958657 created "2018-10-26" @default.
- W2897958657 creator A5075663080 @default.
- W2897958657 creator A5078608631 @default.
- W2897958657 creator A5084580982 @default.
- W2897958657 date "2018-10-12" @default.
- W2897958657 modified "2023-09-24" @default.
- W2897958657 title "Segregated encoding of spatiotemporal features in the mouse visual cortex" @default.
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- W2897958657 hasPublicationYear "2018" @default.