FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898003003> ?p ?o ?g. }

• W2898003003 abstract "Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of serious infectious diseases in intensive care units. Novel antibiotic combination therapies are needed to treat serious infectious diseases caused by MRSA. Objectives: Our objective was to evaluate the minimum inhibitory concentrations (MICs) of ceftaroline (CPT), telavancin (TLV), daptomycin (DPC), and vancomycin (VA) alone and in vitro synergistic activity of CPT-TLV, CPT-DPC, and CPT-VA combinations against MRSA isolates. Methods: Fifty MRSA strains isolated from blood (90%) and tracheal aspirate (10%) of patients in intensive care units (ICUs) between 2013 and 2016 were included in the study. The Epsilometer test was used for determining the synergistic activities of antibiotic combinations. We evaluated the synergistic, additive, indifferent, and antagonist effects of MRSA strains by the fractional inhibitory concentration (FIC) index. Results: Of the 50 MRSA strains tested, 100% were susceptible to TLV, DPC, and VA. CPT was detected as resistant in 3 (6%) of the isolates. CPT-TLV, CPT-DPC, and CPT-VA combinations were found to have synergistic effects in 14%, 38%, 10% and additive effects in 40%, 32%, and 22% of the isolates, respectively. No antagonism was detected in any of the combinations. Conclusions: The combination of CPT with DPC showed the best synergy profile among all antibiotic combinations tested against MRSA isolates obtained from patients in ICUs." @default.
• W2898003003 created "2018-10-26" @default.
• W2898003003 creator A5018819158 @default.
• W2898003003 creator A5030211230 @default.
• W2898003003 creator A5032561439 @default.
• W2898003003 creator A5049590815 @default.
• W2898003003 creator A5065949068 @default.
• W2898003003 creator A5074493778 @default.
• W2898003003 date "2018-10-17" @default.
• W2898003003 modified "2023-10-14" @default.
• W2898003003 title "Detection of Synergistic Antimicrobial Activities of Ceftaroline, Telavancin, Daptomycin, and Vancomycin Against Methicillin-Resistant Staphylococcus aureus Strains in Intensive Care Units" @default.
• W2898003003 cites W1511878397 @default.
• W2898003003 cites W1817362387 @default.
• W2898003003 cites W1869062106 @default.
• W2898003003 cites W1878404532 @default.
• W2898003003 cites W1982839622 @default.
• W2898003003 cites W1995489787 @default.
• W2898003003 cites W2003505085 @default.
• W2898003003 cites W2004181955 @default.
• W2898003003 cites W2006006007 @default.
• W2898003003 cites W2016351604 @default.
• W2898003003 cites W2030484760 @default.
• W2898003003 cites W2034179516 @default.
• W2898003003 cites W2041050715 @default.
• W2898003003 cites W2044660954 @default.
• W2898003003 cites W2080944013 @default.
• W2898003003 cites W2092645865 @default.
• W2898003003 cites W2096996011 @default.
• W2898003003 cites W2104589256 @default.
• W2898003003 cites W2120258185 @default.
• W2898003003 cites W2120575175 @default.
• W2898003003 cites W2128245530 @default.
• W2898003003 cites W2131400572 @default.
• W2898003003 cites W2134328505 @default.
• W2898003003 cites W2135788092 @default.
• W2898003003 cites W2144504167 @default.
• W2898003003 cites W2146598854 @default.
• W2898003003 cites W2147240880 @default.
• W2898003003 cites W2155311152 @default.
• W2898003003 cites W2167031235 @default.
• W2898003003 cites W2172031734 @default.
• W2898003003 cites W2344195204 @default.
• W2898003003 cites W2530412655 @default.
• W2898003003 doi "https://doi.org/10.5812/jjm.66445" @default.
• W2898003003 hasPublicationYear "2018" @default.
• W2898003003 type Work @default.
• W2898003003 sameAs 2898003003 @default.
• W2898003003 citedByCount "1" @default.
• W2898003003 countsByYear W28980030032022 @default.
• W2898003003 crossrefType "journal-article" @default.
• W2898003003 hasAuthorship W2898003003A5018819158 @default.
• W2898003003 hasAuthorship W2898003003A5030211230 @default.
• W2898003003 hasAuthorship W2898003003A5032561439 @default.
• W2898003003 hasAuthorship W2898003003A5049590815 @default.
• W2898003003 hasAuthorship W2898003003A5065949068 @default.
• W2898003003 hasAuthorship W2898003003A5074493778 @default.
• W2898003003 hasBestOaLocation W28980030031 @default.
• W2898003003 hasConcept C176947019 @default.
• W2898003003 hasConcept C177713679 @default.
• W2898003003 hasConcept C2777052132 @default.
• W2898003003 hasConcept C2778651397 @default.
• W2898003003 hasConcept C2778980435 @default.
• W2898003003 hasConcept C2779489039 @default.
• W2898003003 hasConcept C2987404301 @default.
• W2898003003 hasConcept C4937899 @default.
• W2898003003 hasConcept C501593827 @default.
• W2898003003 hasConcept C523546767 @default.
• W2898003003 hasConcept C54355233 @default.
• W2898003003 hasConcept C71924100 @default.
• W2898003003 hasConcept C86803240 @default.
• W2898003003 hasConcept C89423630 @default.
• W2898003003 hasConceptScore W2898003003C176947019 @default.
• W2898003003 hasConceptScore W2898003003C177713679 @default.
• W2898003003 hasConceptScore W2898003003C2777052132 @default.
• W2898003003 hasConceptScore W2898003003C2778651397 @default.
• W2898003003 hasConceptScore W2898003003C2778980435 @default.
• W2898003003 hasConceptScore W2898003003C2779489039 @default.
• W2898003003 hasConceptScore W2898003003C2987404301 @default.
• W2898003003 hasConceptScore W2898003003C4937899 @default.
• W2898003003 hasConceptScore W2898003003C501593827 @default.
• W2898003003 hasConceptScore W2898003003C523546767 @default.
• W2898003003 hasConceptScore W2898003003C54355233 @default.
• W2898003003 hasConceptScore W2898003003C71924100 @default.
• W2898003003 hasConceptScore W2898003003C86803240 @default.
• W2898003003 hasConceptScore W2898003003C89423630 @default.
• W2898003003 hasIssue "In Press" @default.
• W2898003003 hasLocation W28980030031 @default.
• W2898003003 hasOpenAccess W2898003003 @default.
• W2898003003 hasPrimaryLocation W28980030031 @default.
• W2898003003 hasRelatedWork W1970719352 @default.
• W2898003003 hasRelatedWork W2009801005 @default.
• W2898003003 hasRelatedWork W2018382434 @default.
• W2898003003 hasRelatedWork W2022769258 @default.
• W2898003003 hasRelatedWork W2100735090 @default.
• W2898003003 hasRelatedWork W2104380773 @default.
• W2898003003 hasRelatedWork W2133736791 @default.
• W2898003003 hasRelatedWork W2151596649 @default.
• W2898003003 hasRelatedWork W2412517736 @default.
• W2898003003 hasRelatedWork W3107914937 @default.
• W2898003003 hasVolume "In Press" @default.

• next