Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898014798> ?p ?o ?g. }
- W2898014798 endingPage "1800358" @default.
- W2898014798 startingPage "1800358" @default.
- W2898014798 abstract "Bone remodeling is strongly linked to external mechanical signals. Such stimuli are widely used in vitro for bone tissue engineering by applying mechanical solicitations to cell cultures so as to trigger specific cell responses. However, the literature highlights considerable variability in devices and protocols. Here the major biological, mechanical, and technical parameters implemented for in vitro tensile loading applications are reviewed. The objective is to identify which values are used most, and whether there is an optimal protocol to obtain a functional tissue-engineering construct. First, a shift that occurred from fundamental comprehension of bone formation, to its application in rebuilt tissues and clinical fields is shown. Despite the lack of standardized protocols, consensual conditions relevant for in vitro bone development, in particular cell differentiation, could be highlighted. Culture processes are guided by physiological considerations, although out-of-range conditions are sometimes used without implying negative results for the development of rebuilt tissue. Consensus can be found on several parameters, such as strain frequency (1 Hz) or the use of rest periods, but other points have not yet been fully established, especially synergies with other solicitations. It is believed that the present work will be useful to develop new tissue-engineering processes based on stretching." @default.
- W2898014798 created "2018-10-26" @default.
- W2898014798 creator A5000362843 @default.
- W2898014798 creator A5013116153 @default.
- W2898014798 creator A5042541404 @default.
- W2898014798 date "2018-11-19" @default.
- W2898014798 modified "2023-09-26" @default.
- W2898014798 title "In Vitro Bone Cell Response to Tensile Mechanical Solicitations: Is There an Optimal Protocol?" @default.
- W2898014798 cites W1129936108 @default.
- W2898014798 cites W1528826152 @default.
- W2898014798 cites W1628998952 @default.
- W2898014798 cites W1916156238 @default.
- W2898014798 cites W1922316858 @default.
- W2898014798 cites W1955663152 @default.
- W2898014798 cites W1967651912 @default.
- W2898014798 cites W1967966539 @default.
- W2898014798 cites W1970086540 @default.
- W2898014798 cites W1974394551 @default.
- W2898014798 cites W1974489896 @default.
- W2898014798 cites W1976943496 @default.
- W2898014798 cites W1985371035 @default.
- W2898014798 cites W1986746924 @default.
- W2898014798 cites W1990495894 @default.
- W2898014798 cites W1990949147 @default.
- W2898014798 cites W1991103035 @default.
- W2898014798 cites W1993727468 @default.
- W2898014798 cites W1994699261 @default.
- W2898014798 cites W1997450801 @default.
- W2898014798 cites W1999235348 @default.
- W2898014798 cites W2000904875 @default.
- W2898014798 cites W2005098603 @default.
- W2898014798 cites W2008901370 @default.
- W2898014798 cites W2010635910 @default.
- W2898014798 cites W2019212954 @default.
- W2898014798 cites W2038021740 @default.
- W2898014798 cites W2041179972 @default.
- W2898014798 cites W2041181827 @default.
- W2898014798 cites W2042767306 @default.
- W2898014798 cites W2043503863 @default.
- W2898014798 cites W2043567886 @default.
- W2898014798 cites W2044691550 @default.
- W2898014798 cites W2044909797 @default.
- W2898014798 cites W2048492086 @default.
- W2898014798 cites W2051926344 @default.
- W2898014798 cites W2054756968 @default.
- W2898014798 cites W2055364790 @default.
- W2898014798 cites W2065422661 @default.
- W2898014798 cites W2072311348 @default.
- W2898014798 cites W2076128323 @default.
- W2898014798 cites W2077559627 @default.
- W2898014798 cites W2083116970 @default.
- W2898014798 cites W2084687998 @default.
- W2898014798 cites W2086145297 @default.
- W2898014798 cites W2086269269 @default.
- W2898014798 cites W2089194398 @default.
- W2898014798 cites W2093323249 @default.
- W2898014798 cites W2093457976 @default.
- W2898014798 cites W2108082833 @default.
- W2898014798 cites W2109771654 @default.
- W2898014798 cites W2110137500 @default.
- W2898014798 cites W2113330475 @default.
- W2898014798 cites W2114495080 @default.
- W2898014798 cites W2119838587 @default.
- W2898014798 cites W2120188930 @default.
- W2898014798 cites W2121071502 @default.
- W2898014798 cites W2122965155 @default.
- W2898014798 cites W2124195334 @default.
- W2898014798 cites W2126545660 @default.
- W2898014798 cites W2130934825 @default.
- W2898014798 cites W2146235933 @default.
- W2898014798 cites W2154292078 @default.
- W2898014798 cites W2155498879 @default.
- W2898014798 cites W2157874578 @default.
- W2898014798 cites W2158196548 @default.
- W2898014798 cites W2159774995 @default.
- W2898014798 cites W2164319357 @default.
- W2898014798 cites W2165327556 @default.
- W2898014798 cites W2169435298 @default.
- W2898014798 cites W2345492078 @default.
- W2898014798 cites W2769521653 @default.
- W2898014798 cites W4252713891 @default.
- W2898014798 cites W939184508 @default.
- W2898014798 doi "https://doi.org/10.1002/biot.201800358" @default.
- W2898014798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30350925" @default.
- W2898014798 hasPublicationYear "2018" @default.
- W2898014798 type Work @default.
- W2898014798 sameAs 2898014798 @default.
- W2898014798 citedByCount "0" @default.
- W2898014798 crossrefType "journal-article" @default.
- W2898014798 hasAuthorship W2898014798A5000362843 @default.
- W2898014798 hasAuthorship W2898014798A5013116153 @default.
- W2898014798 hasAuthorship W2898014798A5042541404 @default.
- W2898014798 hasBestOaLocation W28980147981 @default.
- W2898014798 hasConcept C112950240 @default.
- W2898014798 hasConcept C127413603 @default.
- W2898014798 hasConcept C136229726 @default.
- W2898014798 hasConcept C142724271 @default.
- W2898014798 hasConcept C159985019 @default.