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• W2898020966 abstract "Differential expression profile of microRNAs (miRNAs) could be a diagnosis signature for monitoring gastric cancer (GC) progression. In this study, we focus on the comparison of expression levels of miR-21, miR-25, miR-93, miR-106b, and miR-375 during the sequential pattern of GC development, including normal gastric, gastric dysplasia, and GC sample.We used SYBR Green-based quantitative-PCR to quantify miRNAs expression.Our analysis revealed the increased expression levels of miR-21 (p = 0.034), miR-25 (p = 0.0003), miR-93 (p = 0.0406), and miR-106b (p = 0.023) in GC samples. In addition, GC patients with positive lymph node metastasis showed the up-regulation of miR-25, miR-93, and miR-106b (p < 0.05).Our findings suggested that the expression of miR-21, miR-25, miR-93, and miR-106b altered in GC, and some of them may be further investigated as biomarkers for GC early detection and prognosis prediction." @default.
• W2898020966 created "2018-10-26" @default.
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• W2898020966 date "2018-11-01" @default.
• W2898020966 modified "2023-10-05" @default.
• W2898020966 title "Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer" @default.
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• W2898020966 doi "https://doi.org/10.29252/.22.6.367" @default.
• W2898020966 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6305817" @default.
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