Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898025526> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2898025526 endingPage "490" @default.
- W2898025526 startingPage "486" @default.
- W2898025526 abstract "Evolution of hepatitis B virus (HBV) is a mystery and caused mainly by genomic mutations as well as recombination. Viral evolution may be responsible for increasing disease severity and render resistance to the existing treatment processes. HBV/C2 strain is associated with chronicity, which may progress to the liver cirrhosis and hepatocellular carcinoma. Furthermore, HBV/C2 strain is highly prevalent in the chronic hepatitis B patients in Bangladesh. Hence, the molecular evolution of that strain and its disease pattern need to be uncovered. Herein, the purpose of this study is to determine the potential mutations of HBV complete genome sequences isolated in Bangladesh and the molecular evolution of HBV/C2 strain. Mutation analysis of the total 57 complete genome sequences of HBV in Bangladesh revealed that 42.11%, 12.28%, 7.02% and 3.51% of the strains were vaccine resistant, HBsAg detection escape, HBV immunoglobulin escape, multi-drug resistant respectively. Furthermore, of the vaccine resistant strains, 16.67% were observed resistant to both vaccine, HBsAg detection and immunoglobulin escape. Bayesian skyline analysis with 462 HBV/C2 strains from 2000 to 2017 revealed the evolution of the strain was in nineteenth century with two rapid sharp increases in the genetic diversity at the end of the twentieth century and then a sudden decrease in the early twenty-first century as observed in C and X gene analysis. This study may help researchers and clinicians to get a better knowledge about the emergence and evolution of HBV/C2 strain that may help to find a proper treatment strategy against hepatitis B." @default.
- W2898025526 created "2018-10-26" @default.
- W2898025526 creator A5006558425 @default.
- W2898025526 creator A5035678510 @default.
- W2898025526 creator A5045289344 @default.
- W2898025526 creator A5049924563 @default.
- W2898025526 creator A5087891779 @default.
- W2898025526 date "2018-10-17" @default.
- W2898025526 modified "2023-09-24" @default.
- W2898025526 title "Molecular evolution and genomics of hepatitis B virus subgenotype C2 strain predominant in the chronic patients in Bangladesh" @default.
- W2898025526 cites W1744635217 @default.
- W2898025526 cites W1829479344 @default.
- W2898025526 cites W1973707041 @default.
- W2898025526 cites W1986188955 @default.
- W2898025526 cites W2026062398 @default.
- W2898025526 cites W2061734833 @default.
- W2898025526 cites W207152389 @default.
- W2898025526 cites W2085154250 @default.
- W2898025526 cites W2099238509 @default.
- W2898025526 cites W2152207030 @default.
- W2898025526 cites W2165782847 @default.
- W2898025526 cites W2168226672 @default.
- W2898025526 cites W2223286010 @default.
- W2898025526 cites W2511383417 @default.
- W2898025526 cites W2569483801 @default.
- W2898025526 cites W2612347515 @default.
- W2898025526 cites W2772739091 @default.
- W2898025526 cites W2789708553 @default.
- W2898025526 cites W2816197187 @default.
- W2898025526 cites W2884591114 @default.
- W2898025526 cites W2891732365 @default.
- W2898025526 doi "https://doi.org/10.1007/s13337-018-0497-6" @default.
- W2898025526 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6261884" @default.
- W2898025526 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30539051" @default.
- W2898025526 hasPublicationYear "2018" @default.
- W2898025526 type Work @default.
- W2898025526 sameAs 2898025526 @default.
- W2898025526 citedByCount "3" @default.
- W2898025526 countsByYear W28980255262019 @default.
- W2898025526 countsByYear W28980255262020 @default.
- W2898025526 countsByYear W28980255262023 @default.
- W2898025526 crossrefType "journal-article" @default.
- W2898025526 hasAuthorship W2898025526A5006558425 @default.
- W2898025526 hasAuthorship W2898025526A5035678510 @default.
- W2898025526 hasAuthorship W2898025526A5045289344 @default.
- W2898025526 hasAuthorship W2898025526A5049924563 @default.
- W2898025526 hasAuthorship W2898025526A5087891779 @default.
- W2898025526 hasBestOaLocation W28980255262 @default.
- W2898025526 hasConcept C104317684 @default.
- W2898025526 hasConcept C105702510 @default.
- W2898025526 hasConcept C141231307 @default.
- W2898025526 hasConcept C159047783 @default.
- W2898025526 hasConcept C2522874641 @default.
- W2898025526 hasConcept C2777382497 @default.
- W2898025526 hasConcept C2777410769 @default.
- W2898025526 hasConcept C2778019345 @default.
- W2898025526 hasConcept C2778022156 @default.
- W2898025526 hasConcept C2780593183 @default.
- W2898025526 hasConcept C54355233 @default.
- W2898025526 hasConcept C86803240 @default.
- W2898025526 hasConceptScore W2898025526C104317684 @default.
- W2898025526 hasConceptScore W2898025526C105702510 @default.
- W2898025526 hasConceptScore W2898025526C141231307 @default.
- W2898025526 hasConceptScore W2898025526C159047783 @default.
- W2898025526 hasConceptScore W2898025526C2522874641 @default.
- W2898025526 hasConceptScore W2898025526C2777382497 @default.
- W2898025526 hasConceptScore W2898025526C2777410769 @default.
- W2898025526 hasConceptScore W2898025526C2778019345 @default.
- W2898025526 hasConceptScore W2898025526C2778022156 @default.
- W2898025526 hasConceptScore W2898025526C2780593183 @default.
- W2898025526 hasConceptScore W2898025526C54355233 @default.
- W2898025526 hasConceptScore W2898025526C86803240 @default.
- W2898025526 hasIssue "4" @default.
- W2898025526 hasLocation W28980255261 @default.
- W2898025526 hasLocation W28980255262 @default.
- W2898025526 hasLocation W28980255263 @default.
- W2898025526 hasLocation W28980255264 @default.
- W2898025526 hasOpenAccess W2898025526 @default.
- W2898025526 hasPrimaryLocation W28980255261 @default.
- W2898025526 hasRelatedWork W2002144368 @default.
- W2898025526 hasRelatedWork W2058381089 @default.
- W2898025526 hasRelatedWork W2064248292 @default.
- W2898025526 hasRelatedWork W2065538639 @default.
- W2898025526 hasRelatedWork W2089670318 @default.
- W2898025526 hasRelatedWork W2095133085 @default.
- W2898025526 hasRelatedWork W2369572641 @default.
- W2898025526 hasRelatedWork W3112727549 @default.
- W2898025526 hasRelatedWork W3216862539 @default.
- W2898025526 hasRelatedWork W4323647428 @default.
- W2898025526 hasVolume "29" @default.
- W2898025526 isParatext "false" @default.
- W2898025526 isRetracted "false" @default.
- W2898025526 magId "2898025526" @default.
- W2898025526 workType "article" @default.