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• W2898029254 abstract "Recent studies suggest a role of the autoimmune system dysregulation in Frontotemporal dementia (FTD). In the present study, we performed a broad immunological screening in a large sample of sporadic FTD patients. We reported a significant increase of antinuclear autoantibodies (ANA) positivity in 100 FTD patients as compared to 100 healthy controls (HC) (60% vs. 13%, p < .001). In FTD, ANA-positive and ANA-negative patients did not differ for any clinical feature. These data extend and further confirm autoimmune dysregulation in FTD. However, it still remains to be clarified whether these antibodies have a potential pathogenic role or represent simply an epiphenomenon." @default.
• W2898029254 created "2018-10-26" @default.
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• W2898029254 date "2018-12-01" @default.
• W2898029254 modified "2023-10-10" @default.
• W2898029254 title "Antinuclear antibodies in Frontotemporal Dementia: the tip's of autoimmunity iceberg?" @default.
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• W2898029254 doi "https://doi.org/10.1016/j.jneuroim.2018.10.006" @default.
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