FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898037175> ?p ?o ?g. }

• W2898037175 endingPage "110" @default.
• W2898037175 startingPage "98" @default.
• W2898037175 abstract "Background: Hemodialysis (HD) patients with secondary Hyperparathyroidism (s-HPT) are exposed to increased inflammation and oxidative stress. In HD patients, oxidized albumin is a reliable marker of oxidative stress and its clinical significance has been rarely studied. Objective: The objective of this study was to evaluate Cys34 Human Serum Albumin (HSA) as oxidative stress biomarker in HD patients with s-HPT and its relationship with inflammation on bone turnover markers during oral calcitriol supplementation for vitamin D. Patients and Methods: Fifteen stable hemodialysis patients with s-HPT (mean age 48.67±8.15, 11 males and 4 females) were used in the experiment to receive calcitriol treatment for 16 weeks (0.25mcg or 0.5 mcg once a day according to serum level of Ca and P for each). The changes in the serum biochemical parameters (Ca, P, ALP, and iPTH), inflammatory markers (CRP and IL-6 levels) and serum oxidative stress condition (SOD, IS and albumin ratio HNA/HMA) were evaluated before and at 8 and 16 weeks of calcitriol treatment. The correlations between those factors were studied. Results: All patients responded to oral calcitriol therapy, with a significant decrease in the serum iPTH. The results showed that calcitriol could effectively suppress iPTH secretion with a significant elevation of serum Ca and P but ALP remained unchanged during the study. It can also effectively reduce the inflammatory markers (CRP and IL-6), while increasing the oxidative markers (SOD and IS). Oxidative albumin ratio HNA/HMA showed a significant ( p =0.001) reduction after 16 weeks of calcitriol treatment and the redox state of HSA showed a positive prediction for hyperparathyroidism and for inflammation. Conclusion: The redox state of HSA could be used as a predictor for monitoring hyperparathyroidism and inflammation during calcitriol treatment by retarding albumin oxidation in HD patients with secondary hyperparathyroidism." @default.
• W2898037175 created "2018-10-26" @default.
• W2898037175 creator A5019048069 @default.
• W2898037175 creator A5028057428 @default.
• W2898037175 creator A5033728832 @default.
• W2898037175 creator A5068489489 @default.
• W2898037175 date "2018-10-18" @default.
• W2898037175 modified "2023-10-15" @default.
• W2898037175 title "Redox State of Human Serum Albumin and Inflammatory Biomarkers in Hemodialysis Patients with Secondary Hyperparathyroidism During Oral Calcitriol Supplementation for Vitamin D" @default.
• W2898037175 cites W1515971740 @default.
• W2898037175 cites W1533415810 @default.
• W2898037175 cites W1751540524 @default.
• W2898037175 cites W1977531987 @default.
• W2898037175 cites W1978017467 @default.
• W2898037175 cites W1980038094 @default.
• W2898037175 cites W1987209581 @default.
• W2898037175 cites W2021514219 @default.
• W2898037175 cites W2024559429 @default.
• W2898037175 cites W2025029450 @default.
• W2898037175 cites W2028632485 @default.
• W2898037175 cites W2032818619 @default.
• W2898037175 cites W2034633126 @default.
• W2898037175 cites W2036123882 @default.
• W2898037175 cites W2036564546 @default.
• W2898037175 cites W2040953528 @default.
• W2898037175 cites W2041288922 @default.
• W2898037175 cites W2053375354 @default.
• W2898037175 cites W2059628172 @default.
• W2898037175 cites W2062502161 @default.
• W2898037175 cites W2064545708 @default.
• W2898037175 cites W2065726646 @default.
• W2898037175 cites W2068906486 @default.
• W2898037175 cites W2069537563 @default.
• W2898037175 cites W2079932872 @default.
• W2898037175 cites W2080387599 @default.
• W2898037175 cites W2083916800 @default.
• W2898037175 cites W2086874396 @default.
• W2898037175 cites W2091343852 @default.
• W2898037175 cites W2095527531 @default.
• W2898037175 cites W2097105350 @default.
• W2898037175 cites W2107207648 @default.
• W2898037175 cites W2113356410 @default.
• W2898037175 cites W2134172788 @default.
• W2898037175 cites W2145632027 @default.
• W2898037175 cites W2160985613 @default.
• W2898037175 cites W2162129240 @default.
• W2898037175 cites W2162757298 @default.
• W2898037175 cites W2280737718 @default.
• W2898037175 cites W2525261956 @default.
• W2898037175 cites W4244621157 @default.
• W2898037175 doi "https://doi.org/10.2174/1874104501812010098" @default.
• W2898037175 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6198414" @default.
• W2898037175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30450134" @default.
• W2898037175 hasPublicationYear "2018" @default.
• W2898037175 type Work @default.
• W2898037175 sameAs 2898037175 @default.
• W2898037175 citedByCount "12" @default.
• W2898037175 countsByYear W28980371752020 @default.
• W2898037175 countsByYear W28980371752021 @default.
• W2898037175 countsByYear W28980371752023 @default.
• W2898037175 crossrefType "journal-article" @default.
• W2898037175 hasAuthorship W2898037175A5019048069 @default.
• W2898037175 hasAuthorship W2898037175A5028057428 @default.
• W2898037175 hasAuthorship W2898037175A5033728832 @default.
• W2898037175 hasAuthorship W2898037175A5068489489 @default.
• W2898037175 hasBestOaLocation W28980371751 @default.
• W2898037175 hasConcept C124490489 @default.
• W2898037175 hasConcept C126322002 @default.
• W2898037175 hasConcept C134018914 @default.
• W2898037175 hasConcept C165616093 @default.
• W2898037175 hasConcept C2775945674 @default.
• W2898037175 hasConcept C2776079296 @default.
• W2898037175 hasConcept C2776125364 @default.
• W2898037175 hasConcept C2776151105 @default.
• W2898037175 hasConcept C2776914184 @default.
• W2898037175 hasConcept C2778063415 @default.
• W2898037175 hasConcept C2778401633 @default.
• W2898037175 hasConcept C2778838027 @default.
• W2898037175 hasConcept C2781208988 @default.
• W2898037175 hasConcept C519063684 @default.
• W2898037175 hasConcept C71924100 @default.
• W2898037175 hasConceptScore W2898037175C124490489 @default.
• W2898037175 hasConceptScore W2898037175C126322002 @default.
• W2898037175 hasConceptScore W2898037175C134018914 @default.
• W2898037175 hasConceptScore W2898037175C165616093 @default.
• W2898037175 hasConceptScore W2898037175C2775945674 @default.
• W2898037175 hasConceptScore W2898037175C2776079296 @default.
• W2898037175 hasConceptScore W2898037175C2776125364 @default.
• W2898037175 hasConceptScore W2898037175C2776151105 @default.
• W2898037175 hasConceptScore W2898037175C2776914184 @default.
• W2898037175 hasConceptScore W2898037175C2778063415 @default.
• W2898037175 hasConceptScore W2898037175C2778401633 @default.
• W2898037175 hasConceptScore W2898037175C2778838027 @default.
• W2898037175 hasConceptScore W2898037175C2781208988 @default.
• W2898037175 hasConceptScore W2898037175C519063684 @default.
• W2898037175 hasConceptScore W2898037175C71924100 @default.
• W2898037175 hasIssue "1" @default.
• W2898037175 hasLocation W28980371751 @default.

• next