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- W2898045139 abstract "The interrelationship of delirium, post-operative cognitive decline, and dementia remain unclear. The goals of this presentation are to: (1) examine the inter-relationship of delirium and post-operative cognitive decline; (2) examine potential risk factors associated with both conditions; and (3) determine long-term cognitive and functional outcomes associated with delirium and post-operative cognitive decline. For this study, we will utilize an ongoing, longitudinal cohort study of 560 older adults without clinical evidence of dementia who underwent major surgery. All patients were well-characterized at baseline, and have achieved long-term follow-up to 3 years (to date). Detailed information on epidemiologic factors, blood markers (ApoE, cytokines, proteomics), MRI markers (DTI, ASL, volumetrics, WMH), serial neuropsychological testing, frailty, and functional outcome measures will allow us to probe important risk factors (including vascular risk factors) and outcomes. The results presented may help to elucidate the complex interrelationship of delirium, post-operative cognitive decline, and early dementia -- along with potential risk factors and associated clinical outcomes." @default.
- W2898045139 created "2018-10-26" @default.
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- W2898045139 date "2018-07-01" @default.
- W2898045139 modified "2023-10-16" @default.
- W2898045139 title "F3‐01‐02: DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE: INTER‐RELATIONSHIP AND OUTCOMES" @default.
- W2898045139 doi "https://doi.org/10.1016/j.jalz.2018.06.2741" @default.
- W2898045139 hasPublicationYear "2018" @default.
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