Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898059293> ?p ?o ?g. }
- W2898059293 endingPage "395" @default.
- W2898059293 startingPage "388" @default.
- W2898059293 abstract "Responsive neurostimulation (RNS) has recently emerged as a safe and effective treatment for some patients with medically refractory focal epilepsy who are not candidates for surgical resection. Responsive neurostimulation involves an implanted neurostimulator and intracranial leads that detect incipient seizures and respond with electrical counterstimulation. Over 1800 patients have been treated with RNS since its FDA approval in 2013. Despite its widespread use, however, RNS presents distinct challenges for clinicians. What types of patients are most well-suited for treatment with RNS? Given the availability of two other neurostimulation modalities, vagus nerve stimulation (VNS) and thalamic deep brain stimulation (DBS), what patient characteristics favor or disfavor RNS? Once RNS candidates are identified, lead placement presents another challenge. Unlike VNS and thalamic DBS, which both involve prespecified electrode locations, RNS involves intracranial strip and/or depth electrodes that can be flexibly configured based on knowledge of the seizure onset zone. The efficacy of RNS may depend on optimal lead configuration, but there are few resources to guide clinicians in formulating lead placement strategies. Here, we address these challenges, first by reviewing clinical trial data supporting the safety and efficacy of RNS. Then, through a series of clinical vignettes from our center, we provide a framework for RNS patient selection. For each clinical scenario, we illustrate typical strategies for RNS lead placement. We outline considerations for choosing among available neurostimulation devices based on their intrinsic features. For example, a unique feature of RNS is that the neurostimulator provides chronic electrocorticography (ECoG), which has powerful diagnostic potential. We highlight emerging applications of chronic ECoG, and we discuss how the limitations of RNS will inform development of next-generation devices." @default.
- W2898059293 created "2018-10-26" @default.
- W2898059293 creator A5017216339 @default.
- W2898059293 creator A5078190790 @default.
- W2898059293 date "2018-11-01" @default.
- W2898059293 modified "2023-10-17" @default.
- W2898059293 title "Responsive neurostimulation: Candidates and considerations" @default.
- W2898059293 cites W1533692490 @default.
- W2898059293 cites W1546583880 @default.
- W2898059293 cites W1911030429 @default.
- W2898059293 cites W1965790293 @default.
- W2898059293 cites W1966242247 @default.
- W2898059293 cites W1970117905 @default.
- W2898059293 cites W1984865568 @default.
- W2898059293 cites W1995098194 @default.
- W2898059293 cites W1999323045 @default.
- W2898059293 cites W2009253761 @default.
- W2898059293 cites W2014414713 @default.
- W2898059293 cites W2018536252 @default.
- W2898059293 cites W2024039918 @default.
- W2898059293 cites W2024956705 @default.
- W2898059293 cites W2028681020 @default.
- W2898059293 cites W2038606869 @default.
- W2898059293 cites W2049822525 @default.
- W2898059293 cites W2059497817 @default.
- W2898059293 cites W2088329603 @default.
- W2898059293 cites W2090276138 @default.
- W2898059293 cites W2119130526 @default.
- W2898059293 cites W2127296441 @default.
- W2898059293 cites W2141807669 @default.
- W2898059293 cites W2146775383 @default.
- W2898059293 cites W2151945944 @default.
- W2898059293 cites W2154214065 @default.
- W2898059293 cites W2158334924 @default.
- W2898059293 cites W2168067596 @default.
- W2898059293 cites W2188946647 @default.
- W2898059293 cites W2193866129 @default.
- W2898059293 cites W2288238997 @default.
- W2898059293 cites W2301514678 @default.
- W2898059293 cites W2465489214 @default.
- W2898059293 cites W2495094145 @default.
- W2898059293 cites W2578930960 @default.
- W2898059293 cites W2605041831 @default.
- W2898059293 cites W2607074866 @default.
- W2898059293 cites W2738797743 @default.
- W2898059293 cites W2754836112 @default.
- W2898059293 cites W2769126173 @default.
- W2898059293 cites W2772152119 @default.
- W2898059293 cites W2782520840 @default.
- W2898059293 cites W2783356641 @default.
- W2898059293 cites W2785916808 @default.
- W2898059293 cites W2789261276 @default.
- W2898059293 cites W2799980322 @default.
- W2898059293 cites W2800962323 @default.
- W2898059293 cites W954125256 @default.
- W2898059293 doi "https://doi.org/10.1016/j.yebeh.2018.09.032" @default.
- W2898059293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30355456" @default.
- W2898059293 hasPublicationYear "2018" @default.
- W2898059293 type Work @default.
- W2898059293 sameAs 2898059293 @default.
- W2898059293 citedByCount "43" @default.
- W2898059293 countsByYear W28980592932019 @default.
- W2898059293 countsByYear W28980592932020 @default.
- W2898059293 countsByYear W28980592932021 @default.
- W2898059293 countsByYear W28980592932022 @default.
- W2898059293 countsByYear W28980592932023 @default.
- W2898059293 crossrefType "journal-article" @default.
- W2898059293 hasAuthorship W2898059293A5017216339 @default.
- W2898059293 hasAuthorship W2898059293A5078190790 @default.
- W2898059293 hasConcept C126322002 @default.
- W2898059293 hasConcept C15744967 @default.
- W2898059293 hasConcept C169760540 @default.
- W2898059293 hasConcept C24998067 @default.
- W2898059293 hasConcept C2776443511 @default.
- W2898059293 hasConcept C2778186239 @default.
- W2898059293 hasConcept C2778542668 @default.
- W2898059293 hasConcept C2779134260 @default.
- W2898059293 hasConcept C2779734285 @default.
- W2898059293 hasConcept C2780087125 @default.
- W2898059293 hasConcept C2780117969 @default.
- W2898059293 hasConcept C2780803581 @default.
- W2898059293 hasConcept C2781404750 @default.
- W2898059293 hasConcept C71924100 @default.
- W2898059293 hasConceptScore W2898059293C126322002 @default.
- W2898059293 hasConceptScore W2898059293C15744967 @default.
- W2898059293 hasConceptScore W2898059293C169760540 @default.
- W2898059293 hasConceptScore W2898059293C24998067 @default.
- W2898059293 hasConceptScore W2898059293C2776443511 @default.
- W2898059293 hasConceptScore W2898059293C2778186239 @default.
- W2898059293 hasConceptScore W2898059293C2778542668 @default.
- W2898059293 hasConceptScore W2898059293C2779134260 @default.
- W2898059293 hasConceptScore W2898059293C2779734285 @default.
- W2898059293 hasConceptScore W2898059293C2780087125 @default.
- W2898059293 hasConceptScore W2898059293C2780117969 @default.
- W2898059293 hasConceptScore W2898059293C2780803581 @default.
- W2898059293 hasConceptScore W2898059293C2781404750 @default.
- W2898059293 hasConceptScore W2898059293C71924100 @default.
- W2898059293 hasLocation W28980592931 @default.