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• W2898059395 abstract "Nesfatin-1 and HSP70 are involved in the regulating mechanisms of insulin and glucose metabolism. The aim of this study was to evaluate the effects of 10 weeks of resistance and endurance exercise training on the serum levels of nesfatin-1, HSP70 and insulin resistance (IR) in women with type 2 diabetes. 26 women with type 2 diabetes were selected using purposive sampling and were randomly divided into three groups. 10 subjects participated in the resistance training group (3 sessions per week, exercising with 30–80% of one repetition maximum (1RM)), 8 subjects participated in the endurance training group (3 sessions per week, exercising with 40–80% of maximum heart rate (HR max), for 20–45 minutes), and 8 subjects were placed in the control group who did not engage in any physical exercise during the study period. Blood samples were collected after a 12 hour [overnight] fast in order to evaluate nesfatin-1, HSP70, insulin and glucose levels in the pre- and post-tests. The obtained data were analyzed using the Kolmogorov-Smirnov (K-S) test, paired-samples t-test, one-way ANOVA and LSD post-hoc test in SPSS software, version 21 at the significance level of α <0.05. There was a significant increase in nesfatin-1 levels and a significant decrease in HSP70 levels of the resistance training group, (P < 0.05), whereas no significant changes were observed in nesfatin-1 and HSP70 levels of the endurance training group (P > 0.05). Glucose levels, insulin resistance (HOMA1-IR) and body composition indices (except for WHR) significantly decreased in both training groups (P < 0.05). However, there were no significant changes in insulin levels of the training groups (P > 0.05). Moreover, comparing the pre- and post-test levels of glucose changes, a significant difference was observed in the resistance and endurance training groups but not in the control group (P < 0.05). Resistance and endurance training are recommended as complementary therapy for women with type 2 diabetes mellitus. la nesfatine 1 et l’HSP70 sont impliquées dans l’action de l’insuline et dans la régulation du métabolisme glucidique. L’objectif de cette recherche est d’analyser les effets de 10 semaines d’exercice en résistance et endurance sur les concentrations sériques de nesfatine 1 et d’HSP70 et de la résistance du corps de femmes diabétiques de type 2. Les investigateurs ont randomisé 26 patientes diabétiques qui ont été divisées en 3 groupes. 10 femmes réalisaient l’exercice en résistance (3 fois par semaines 60 minutes à une intensité de 30–80 % d’une repetition maximale) [1RM]. 8femmes réalisaient un exercice en endurance (3fois 20–40 minutes par semaine à une intensité de 40–80 % de la fréquence cardiaque maximale). Les 8 personnes du groupe contrôle n’avaient pas d’activité physique. Les échantillons de sang étaient prélevés après 12 heures de jeûne pour le dosage la Nesfatine 1, de HSP 70, de l’insuline et du glucose avant et après le protocole. Les données ont été analyses avec le test de Kolmogrov-Smirnov (K-S), le test t de Student pour valeurs appariées, l’analyse de variance à une voie, et le test de Différence Significative Minimale (LSD) de Fisher, avec la version de SPSS 21. L’exercice en résistance augmentait la Nesfatine 1 et diminuait l’HSP70, alors que ces paramètres n’étaient pas significativement modifies par l’exercice en endurance. Résistance et endurance diminuaient toutes deux la glycémie, l’insulino-résistance, et les parameters d’adiposité (sauf le rapport taille sur hanche). Par contre ces entrainements ne diminuaient significativement pas l’insulinémie. Les exercices en résistance et en endurance ont des effets bénéfiques distincts chez les patientes atteintes de diabète de type 2." @default.
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• W2898059395 date "2019-02-01" @default.
• W2898059395 modified "2023-10-02" @default.
• W2898059395 title "The Effects of Resistance and Endurance Training on Levels of Nesfatin-1, HSP70, Insulin Resistance and Body Composition in Women with Type 2 Diabetes Mellitus" @default.
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• W2898059395 doi "https://doi.org/10.1016/j.scispo.2018.04.010" @default.
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