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- W2898063119 abstract "Anti-thrombotic management of percutaneous coronary intervention and atrial fibrillation relies on dual antiplatelet therapy and anticoagulation respectively. Because of people ageing, the coexistence of coronary artery disease and atrial fibrillation is increasing. This coexistence raises concerns about the anti-thrombotic strategy, particularly about the association of dual antiplatelet therapy and anticoagulation, known as triple therapy. This triple therapy is responsible for a dramatic increase in bleeding risk (3-4 fold) especially in elderlies. However, older patients are also at increased risk of ischemic events. In this setting, dual anti-thrombotic strategies combining non-vitamin K oral anticoagulants and a P2Y12 inhibitor have been developed. These strategies provide a net benefit by reducing bleeding events. Therefore, they are becoming an attractive alternative, especially for frailer patient. This article reviews the rational, risks and strategies of anti-thrombotic therapy in elderly people with coronary artery disease and atrial fibrillation." @default.
- W2898063119 created "2018-10-26" @default.
- W2898063119 creator A5044604637 @default.
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- W2898063119 date "2018-12-01" @default.
- W2898063119 modified "2023-09-28" @default.
- W2898063119 title "Anticoagulants oraux chez le sujet âgé coronarien en fibrillation atriale" @default.
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- W2898063119 doi "https://doi.org/10.1016/j.ancard.2018.09.013" @default.
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